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Cited by 37Urinary Bladder and Prostate ResearchPelvic floor disorders treatmentsVagus Nerve Stimulation Research

The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.

Posterior Tibial Nerve Stimulation for Overactive Bladder: Mechanism, Classification, and Management Outlines

Open access

Abstract

Purpose of the Review . Posterior tibial nerve stimulation (PTNS) techniques have dramatically grown after approval to manage overactive bladder (OAB). The present review will focus on the most current data on PTNS types (percutaneous, transcutaneous, and implant) and their mechanism of action, safety, efficacy, advantages, drawbacks, limitation, and clinical applications. Recent Findings . The present review described the recent studies that addressed the tibial nerve stimulation role in OAB management. BlueWind RENOVA system, Bioness StimRouter, and eCoin are examples of emerging technologies that have evolved from interval sessions (percutaneous PTNS and transcutaneous PTNS) to continuous stimulation (implants). These can be efficiently managed at home by patients with minimum burden on the health system and fewer visits, especially in the COVID‐19 pandemic. Summary . Our review shows that the tibial nerve stimulation advancements in OAB treatment have been rapidly increasing over the recent years. It is minimally invasive and effective, similar to sacral nerve stimulation (SNM), but less aggressive. Implantable PTNS has been promised in terms of efficacy, safety, and high acceptance rate. However, evidence is still limited to short‐term trials, and tolerability, method, and drawbacks remain challenges.

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Registry

Crossref · 10.1155/2022/2700227

Cites

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Figures

Figure 1 The brain networks that regulate continence and micturition are depicted. Urine storage reflexes. (a). Urine storage reflexes. (b). Urination (or voiding) reflexes the pontine micturition center (PAG).
Figure 1 The brain networks that regulate continence and micturition are depicted. Urine storage reflexes. (a). Urine storage reflexes. (b). Urination (or voiding) reflexes the pontine micturition center (PAG).CC BY · PubMed Central
Figure 2 Posterior tibial nerve anatomy and site of different stimulation modalities. (A) The PTNS needle location; (B) BlueWind RENOVATM device; (C) eCoinTM device; (D) Bioness StimRouter; and (E) StimGuard.
Figure 2 Posterior tibial nerve anatomy and site of different stimulation modalities. (A) The PTNS needle location; (B) BlueWind RENOVATM device; (C) eCoinTM device; (D) Bioness StimRouter; and (E) StimGuard.CC BY · PubMed Central
Figure 3 Diagram illustrating diagnosis of overactive bladder syndrome and role of posterior tibial nerve stimulation in its management. OAB: overactive bladder, UTI: urinary tract infection, SNM: sacral neuromodulation, PTNS: posterior tibial nerve stimulation, and FDA: Food and Drug Administration.
Figure 3 Diagram illustrating diagnosis of overactive bladder syndrome and role of posterior tibial nerve stimulation in its management. OAB: overactive bladder, UTI: urinary tract infection, SNM: sacral neuromodulation, PTNS: posterior tibial nerve stimulation, and FDA: Food and Drug Administration.CC BY · PubMed Central

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Cites

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Research works printed but not linked: 6

  1. Teoli D., 2021, StatPearls
  2. 10.1002/j.2040-4603.2015.tb00596.x · doi:10.1002/j.2040-4603.2015.tb00596.x · Paper page
  3. Feloney M. P., 2022, StatPearls
  4. Granger C. J., 2021, StatPearls
  5. 10.12688/hrbopenres.13107.1 · DOI
  6. 10.1136/bmjopen-2020-039164 · DOI

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Metadata

Authors
Al-Danakh, A., Safi, M., Alradhi, M., Almoiliqy, M., Chen, Q., Al-Nusaif, M., Yang, X., Al-Dherasi, A., Zhu, X., & Yang, D.
Affiliations
  • First Affiliated Hospital of Dalian Medical University (CN)
  • Dalian Medical University (CN)
  • Ibb University (YE)
Corresponding author
  • Zhu, Xinqing
  • Yang, Deyong
Venue
Parkinson's Disease
Publisher
Wiley
Published
2022-01
Volume
2022
Issue
1
Pages
2700227-2700227
ISSN
  • 2042-0080 (ISSN-L)
  • 2090-8083
OpenAlex
W4221003480
Cited by
37
References
81
Citations by year
2026: 9 · 2025: 10 · 2024: 10 · 2023: 4 · 2022: 4
FWCI
1.87
Type
journal article
Language
en
Open access
Locations
  • Parkinson s Disease (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Greater South Information System
Topics
  • Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
  • Health Sciences › Medicine › Urology › Pelvic floor disorders treatments
  • Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
Keywords
posterior tibial nerve stimulation, overactive bladder, percutaneous tibial nerve stimulation, transcutaneous tibial nerve stimulation, ECOIN, continuous stimulation, mechanism of action, treatment efficacy and safety, home-based therapy, COVID-19 pandemic

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.