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Posterior Tibial Nerve Stimulation for Overactive Bladder: Mechanism, Classification, and Management Outlines
Open accessAbstract
Purpose of the Review . Posterior tibial nerve stimulation (PTNS) techniques have dramatically grown after approval to manage overactive bladder (OAB). The present review will focus on the most current data on PTNS types (percutaneous, transcutaneous, and implant) and their mechanism of action, safety, efficacy, advantages, drawbacks, limitation, and clinical applications. Recent Findings . The present review described the recent studies that addressed the tibial nerve stimulation role in OAB management. BlueWind RENOVA system, Bioness StimRouter, and eCoin are examples of emerging technologies that have evolved from interval sessions (percutaneous PTNS and transcutaneous PTNS) to continuous stimulation (implants). These can be efficiently managed at home by patients with minimum burden on the health system and fewer visits, especially in the COVID‐19 pandemic. Summary . Our review shows that the tibial nerve stimulation advancements in OAB treatment have been rapidly increasing over the recent years. It is minimally invasive and effective, similar to sacral nerve stimulation (SNM), but less aggressive. Implantable PTNS has been promised in terms of efficacy, safety, and high acceptance rate. However, evidence is still limited to short‐term trials, and tolerability, method, and drawbacks remain challenges.
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“Such technologies address some of the challenges involved in transcutaneous tibial nerve stimulation, for example, reduced efficiency arising from the skin impedance and improper placement of electrodes by patients, decreasing the efficacy of the therapy [62].”
From Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review (2024) · cites this paper as [62]
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Cited by
Active Neural Interface Circuits and Systems for Selective Control of Peripheral Nerves: A Review
Habibollahi, M., Jiang, D., Lancashire, H. T., & Demosthenous, A. (2024) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2024.3430038 · Cited by 11
“Such technologies address some of the challenges involved in transcutaneous tibial nerve stimulation, for example, reduced efficiency arising from the skin impedance and improper placement of electrodes by patients, decreasing the efficacy of the therapy [62].”
Metadata
- Authors
- Al-Danakh, A., Safi, M., Alradhi, M., Almoiliqy, M., Chen, Q., Al-Nusaif, M., Yang, X., Al-Dherasi, A., Zhu, X., & Yang, D.
- Affiliations
- First Affiliated Hospital of Dalian Medical University (CN)
- Dalian Medical University (CN)
- Ibb University (YE)
- Corresponding author
- Zhu, Xinqing
- Yang, Deyong
- ORCID
- Venue
- Parkinson's Disease
- Publisher
- Wiley
- Published
- 2022-01
- Volume
- 2022
- Issue
- 1
- Pages
- 2700227-2700227
- ISSN
- 2042-0080 (ISSN-L)
- 2090-8083
- PMC
- PMC8984064
- OpenAlex
- W4221003480
- Cited by
- 37
- References
- 81
- Citations by year
- 2026: 9 · 2025: 10 · 2024: 10 · 2023: 4 · 2022: 4
- FWCI
- 1.87
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Parkinson s Disease (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Greater South Information System
- Topics
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Health Sciences › Medicine › Urology › Pelvic floor disorders treatments
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Keywords
- posterior tibial nerve stimulation, overactive bladder, percutaneous tibial nerve stimulation, transcutaneous tibial nerve stimulation, ECOIN, continuous stimulation, mechanism of action, treatment efficacy and safety, home-based therapy, COVID-19 pandemic
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