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Riesgo cardiovascular en sujetos con alta probabilidad de síndrome metabólico y resistencia a la insulina. Estudio DESIRE
Abstract
Introduction and objectives The metabolic syndrome is an association of closely related alterations. The main objective of this study is to know the frequency of the metabolic syndrome and insulin resistance, and their role as cardiovascular risk indicators in an adult population assigned to Primary Care centers in Spain. Methods Subjects > or = 45 years with basal glycemia > or = 90 mg/dl and abdominal circumference > or = 94 cm (men) or > or = 80 cm (women). ATP III modified-criteria were used for the metabolic syndrome and HOMA index > 3.29 was used for insulin resistance. Cardiovascular risk was estimated by the Framingham and SCORE models. Results A total of 2,341 subjects (62 +/- 10 years; 44.6% males) were included. Frequency of metabolic syndrome and insulin resistance was 54.6% (52.5; 56.8) and 56.6% (54.5; 58.7) respectively. Metabolic syndrome was associated to a higher cardiovascular risk score with both Framingham (16 [15; 16] vs 11 [11; 12] p Conclusions Metabolic syndrome and insulin resistance are cardiovascular risk predictors. Early identification of metabolic syndrome by the use of simple clinical measures (basal glycemia and waist circumference) would make the intervention on the different disorders of metabolic syndrome possible.
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“Attrition rate in our study was similar to that previously reported in VLCK diet, high-protein or very-low carbohydrate diets.23, 36, 37”
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Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome
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Goday, A., Bellido, D., Sajoux, I., Crujeiras, A. B., Burguera, B., García-Luna, P. P., Oleaga, A., Moreno, B., & Casanueva, F. F. (2016) · Nutrition & Diabetes · doi:10.1038/nutd.2016.36 · Cited by 258
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Metadata
- Authors
- Goday, A., Gabriel, R., Ascaso, J. F., Franch, J., Ortega, R., Martínez, O., & Lerones, N.
- Venue
- Revista Clínica Española
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 208
- Issue
- 8
- Pages
- 377-385
- ISSN
- 0014-2565
- Cited by
- 15
- References
- 5
- Language
- es
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- Goday, A., Gabriel, R., Ascaso, J. F., Franch, J., Ortega, R., Martínez, O., & Lerones, N. (2008). Riesgo cardiovascular en sujetos con alta probabilidad de síndrome metabólico y resistencia a la insulina. Estudio DESIRE. Revista Clínica Española. https://doi.org/10.1157/13126339
