The prevalence of abnormal glucose regulation in patients with coronary artery disease across EuropeThe Euro Heart Survey on diabetes and the heart
Open accessAbstract
AIM: The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD). METHODS AND RESULTS: The survey engaged 110 centres in 25 countries recruiting 4196 patients referred to a cardiologist due to CAD out of whom 2107 were admitted on an acute basis and 2854 had an elective consultation. Patient data were collected via a web-based case record form. An oral glucose tolerance test (OGTT) was used for the characterisation of the glucose metabolism. Thirty-one per cent of the patients had diabetes. An OGTT was performed on the 1920 patients without known diabetes, of whom 923 had acute and 997 had a stable manifestation of CAD, respectively. In patients with acute CAD, 36% had impaired glucose regulation and 22% newly detected diabetes. In the stable group these proportions were 37% and 14%. CONCLUSION: This survey demonstrates that normal glucose regulation is less common than abnormal glucose regulation in patients with CAD. OGTT easily discloses the glucometabolic state and should be a routine procedure. The knowledge of glucometabolic state among these patients should influence their future management because it has great potential to improve the outcome.
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Some studies suggest performing oral glucose tolerance testing before hospital discharge, but robust data supporting this approach are lacking.
“Some studies suggest performing OGTT before hospital discharge but robust data supporting this approach are lacking.20,21”
From 2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes. (2023) · cites this paper as [21]
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Tuomilehto, J., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Laakso, M., Louheranta, A., Rastas, M., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejm200105033441801 · Cited by 10,873 · see citing works
Haffner, S. M., Lehto, S., Rönnemaa, T., Pyörälä, K., & Laakso, M. (1998) · New England Journal of Medicine · doi:10.1056/nejm199807233390404 · Cited by 7,000 · see citing works
Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections
King, H. O. M., Aubert, R. E., & Herman, W. H. (1998) · Diabetes Care · doi:10.2337/diacare.21.9.1414 · Cited by 6,267 · see citing works
Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial
Chiasson, J.-L., Josse, R. G., Gomis, R., Hanefeld, M., Karasik, A., & Laakso, M. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08905-5 · Cited by 2,543 · see citing works
Capes, S. E., Hunt, D., Malmberg, K., & Gerstein, H. C. (2000) · The Lancet · doi:10.1016/s0140-6736(99)08415-9 · Cited by 2,187 · see citing works
Coutinho, M., Gerstein, H. C., Wang, Y., & Yusuf, S. (1999) · Diabetes Care · doi:10.2337/diacare.22.2.233 · Cited by 1,685 · see citing works
Letter: Grading of angina pectoris.
CAMPEAU, L. A. (1976) · Circulation · doi:10.1161/circ.54.3.947585 · Cited by 1,607 · see citing works
Guidelines for the diagnosis and treatment of chronic heart failure
Remme, W. J. (2001) · European Heart Journal · doi:10.1053/euhj.2001.2783 · Cited by 1,583 · see citing works
Malmberg, K., Rydén, L., Efendic, S., Herlitz, J., Nicol, P., Waldenstrom, A., Wedel, H., & Welin, L. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00126-k · Cited by 1,560 · see citing works
Management of acute myocardial infarction in patients presenting with ST-segment elevation
de Werf, F. V. (2003) · European Heart Journal · doi:10.1016/s0195-668x(02)00618-8 · Cited by 1,441 · see citing works
Norhammar, A., Tenerz, Å., Nilsson, G., Hamsten, A., Efendíc, S., Rydén, L., & Malmberg, K. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09089-x · Cited by 1,112 · see citing works
Bertrand, M. E. (2002) · European Heart Journal · doi:10.1053/euhj.2002.3385 · Cited by 896 · see citing works
Malmberg, K., Norhammar, A., Wedel, H., & Rydén, L. (1999) · Circulation · doi:10.1161/01.cir.99.20.2626 · Cited by 844 · see citing works
Hasdai, D. (2002) · European Heart Journal · doi:10.1053/euhj.2002.3193 · Cited by 771 · see citing works
The DECODE Study Group, & on behalf of the European Diabetes Epidemiology Group (2003) · Diabetes Care · doi:10.2337/diacare.26.3.688 · Cited by 516 · see citing works
Remme, W. J., & Swedberg, K. B. (2002) · European Journal of Heart Failure · doi:10.1016/s1388-9842(01)00231-8 · Cited by 453 · see citing works
Wulffelé, M. G., Kooy, A., de Zeeuw, D., Stehouwer, C. D. A., & Gansevoort, R. T. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01328.x · Cited by 359 · see citing works
Norhammar, A., Malmberg, K., Diderholm, E., Lagerqvist, B., Lindahl, B., Rydén, L., & Wallentin, L. C. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2003.08.050 · Cited by 328 · see citing works
Norhammar, A., Rydén, L., & Malmberg, K. (1999) · Diabetes Care · doi:10.2337/diacare.22.11.1827 · Cited by 316 · see citing works
Bartnik, M., Malmberg, K., Norhammar, A., Tenerz, Å., Öhrvik, J., & Rydén, L. (2004) · European Heart Journal · doi:10.1016/j.ehj.2004.09.021 · Cited by 281 · see citing works
Self-citationOswald, G. A., Smith, C. C. T., Betteridge, D. J., & Yudkin, J. S. (1986) · BMJ · doi:10.1136/bmj.293.6552.917 · Cited by 264 · see citing works
Qiao, Q. (2002) · European Heart Journal · doi:10.1053/euhj.2001.3113 · Cited by 180 · see citing works
Tenerz, A., Norhammar, A., Silveira, A., Hamsten, A., Nilsson, G., Rydén, L., & Malmberg, K. (2003) · Diabetes Care · doi:10.2337/diacare.26.10.2770 · Cited by 139 · see citing works
Norhammar, A., Malmberg, K., Rydén, L., et al. (2003) · PubMed · doi:10.1016/s0195-668x(02)00828-x · Cited by 126 · see citing works
Groups*, T. E. I. A. I., Pyörälà, K., Lehto, S., Bacquer, D. D., SUTTER, J. D., Sans, S., Keil, U., Wood, D., & Backer, G. D. (2004) · Diabetologia · doi:10.1007/s00125-004-1438-z · Cited by 118 · see citing works
TAUBERT, G., Winkelmann, B. R., Schleiffer, T., März, W., Winkler, R., Gök, R., Klein, B., Schneider, S., & Boehm, B. O. (2003) · American Heart Journal · doi:10.1067/mhj.2003.134 · Cited by 111 · see citing works
Bartnik, M., Malmberg, K., Hamsten, A., Efendić, S., Norhammar, A., Silveira, A. M. V., Tenerz, Å., Öhrvik, J., & Rydén, L. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01371.x · Cited by 111 · see citing works
Self-citationDisturbances of Glucose Metabolism in Men Referred for Coronary Arteriography
Kowalska, I., Prokop, J., Bachórzewska-Gajewska, H., Telejko, B., Kinalskal, I., Kochman, W., & Musial, W. J. (2001) · Diabetes Care · doi:10.2337/diacare.24.5.897 · Cited by 89 · see citing works
Schnell, O., Schäfer, O., Kleybrink, S., Doering, W., Standl, E., & Otter, W. (2004) · Diabetes Care · doi:10.2337/diacare.27.2.455 · Cited by 79 · see citing works
Lindahl, B., Weinehall, L., Asplund, K., & Hallmans, G. (1999) · Diabetes Care · doi:10.2337/diacare.22.12.1988 · Cited by 78 · see citing works
Capillary Blood on Filter Paper for Determination of HbA1c by Ion Exchange Chromatography
Jeppsson, J., Jerntorp, P., Almér, L., Persson, R., Ekberg, G., & Sundkvist, G. (1996) · Diabetes Care · doi:10.2337/diacare.19.2.142 · Cited by 70 · see citing works
The oral glucose tolerance test, revisited
Barrett-Connor, E. L. (2002) · European Heart Journal · doi:10.1053/euhj.2002.3243 · Cited by 32 · see citing works
Meier, J. J., Deifuß, S., Gallwitz, B., et al. (2002) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/s-2002-31529 · Cited by 16 · see citing works
Bartnik, M. (2003) · European Heart Journal · doi:10.1016/s0195-668x(03)95619-3 · Cited by 2 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 4
- Julian DG, Bertrand ME, Hjalmarsson A ˚et al. Task force of the ESC: Management of Stable Angina Pectoris. Eur Heart J 1997;18: 394-413.
- Myocardial infarction redefined -A consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the Redefiinition of Myocardial Infarction. Eur Heart J 2000;21:1502-1516.
- Meier JJ, Deifluss S, Gallwitz B et al. Influence of impaired glucose tolerance on long term survival after acute myocardial infarction. The LAngendreer Myocardial infarction and blood glucose in Diabetic patients Assessment (LAMBDA. Dtsch Med Wochenschr 2002;127: 1123-9.
- Knowler WC, Barrett-Connor E, Fowler SE et al. Diabetes Prevention Program Research Group: Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002;356:393-403.
Cited by
Sorted by citations
2023 ESC guidelines for the management of cardiovascular disease in patients with diabetes.
Marx, N., Federici, M., Schütt, K., Müller-Wieland, D., Ajjan, R. A., Antunes, M. J., Christodorescu, R. M., Crawford, C., Di Angelantonio, E., Eliasson, B., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad192 · Cited by 1,642 · see citing works
Malmberg, K., Rydén, L., Wedel, H., Birkeland, K., Bootsma, A., Dickstein, K., Efendic, S., Fisher, M., Hamsten, A., Herlitz, J., et al. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi199 · Cited by 1,048 · see citing works
Kotseva, K., Wood, D., Backer, G. D., Bacquer, D. D., Pyörälä, K., Keil, U., & EUROASPIRE Study Group (2009) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e3283294b1d · Cited by 812 · see citing works
Barr, E. L. M., Zimmet, P. Z., Welborn, T. A., Jolley, D., Magliano, D. J., Dunstan, D. W., Cameron, A. J., Dwyer, T., Taylor, H. R., Tonkin, A. M., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.685628 · Cited by 719 · see citing works
Handelsman, Y., Bloomgarden, Z. T., Grunberger, G., Umpierrez, G., Zimmerman, R. S., Bailey, T. S., Blonde, L., Bray, G. A., Cohen, A. J., Dagogo-Jack, S., et al. (2015) · Endocrine Practice · doi:10.4158/ep15672.glsuppl · Cited by 559 · see citing works
Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part II
Beckman, J. A., Paneni, F., Cosentino, F., & Creager, M. A. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht142 · Cited by 434 · see citing works
Lindeberg, S., Jönsson, T., Granfeldt, Y., Borgstrand, E., Soffman, J., Sjöström, K., & Ahrén, B. (2007) · Diabetologia · doi:10.1007/s00125-007-0716-y · Cited by 273 · see citing works
Adhikari, R., Jha, K., Dardari, Z., Heyward, J., Blumenthal, R. S., Eckel, R. H., Alexander, G. C., & Blaha, M. J. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.121.023811 · Cited by 166 · see citing works
Approaches to prevention of cardiovascular complications and events in diabetes mellitus
Coccheri, S. (2007) · Drugs · doi:10.2165/00003495-200767070-00005 · Cited by 139 · see citing works
Li, S.-N., Wang, X., Zeng, Q.-T., Feng, Y.-B., Cheng, X., Mao, X.-B., Wang, T.-H., & Deng, H.-P. (2009) · Heart and Vessels · doi:10.1007/s00380-008-1137-7 · Cited by 88 · see citing works
Ritsinger, V., Tanoglidi, E., Malmberg, K., Näsman, P., Rydén, L., Tenerz, Å., & Norhammar, A. (2015) · Diabetes and Vascular Disease Research · doi:10.1177/1479164114551746 · Cited by 71 · see citing works
Young, L. H., Viscoli, C. M., Curtis, J. P., Inzucchi, S. E., Schwartz, G. G., Lovejoy, A. M., Furie, K. L., Gorman, M. J., Conwit, R., Abbott, J. D., et al. (2017) · Circulation · doi:10.1161/circulationaha.116.024863 · Cited by 66 · see citing works
New-onset hyperglycemia and acute coronary syndrome: a systematic overview and meta-analysis
Angeli, F., Verdecchia, P., Karthikeyan, G., Mazzotta, G., Pinto, M., Repaci, S., Gatteschi, C., Gentile, G., Cavallini, C., & Reboldi, G. (2010) · Current Diabetes Reviews · doi:10.2174/157339910790909413 · Cited by 48 · see citing works
Goyal, A., Mehta, S. R., Gerstein, H. C., Díaz, R., Afzal, R., Xavier, D., Zhu, J., Pais, P., Lisheng, L., Kazmi, K. A., et al. (2009) · American Heart Journal · doi:10.1016/j.ahj.2008.12.007 · Cited by 35 · see citing works
Mak, K.-H., Vidal-Petiot, E., Young, R., Sorbets, E., Greenlaw, N., Ford, I., Tendera, M., Ferrari, R., Tardif, J.-C., Udell, J. A., et al. (2022) · European Journal of Preventive Cardiology · doi:10.1093/eurjpc/zwab011 · Cited by 39 · see citing works
Kleinherenbrink, W., Osei, E., den Hertog, H. M., & Zandbergen, A. A. M. (2018) · European Journal of Internal Medicine · doi:10.1016/j.ejim.2018.07.001 · Cited by 31 · see citing works
Kuramitsu, S., Yokoi, H., Domei, T., Nomura, A., Watanabe, H., Yamaji, K., Soga, Y., Arita, T., Kondo, K., Shirai, S., et al. (2013) · Cardiovascular Diabetology · doi:10.1186/1475-2840-12-74 · Cited by 26 · see citing works
Han, M., Cao, X., Zhao, C., Yang, L., Yin, N., Shen, P., Zhang, J., Gao, F., Ren, Y., Liang, D., et al. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.544752 · Cited by 10 · see citing works
Management of acute coronary syndromes
Tardif, J.-C., L'Allier, P. L., & Fitchett, D. H. (2018) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2017.10.029 · Cited by 10 · see citing works
Wang, J.-S., Sheu, W. H.-H., Lee, W.-J., Lee, I.-T., Lin, S.-Y., Lee, W.-L., Liang, K.-W., & Lin, S.-J. (2018) · Clinica Chimica Acta · doi:10.1016/j.cca.2018.04.032 · Cited by 5 · see citing works
- Authors
- BARTNIK, M.
- Affiliations
- Karolinska University Hospital (SE)
- Corresponding author
- BARTNIK, M
- ORCID
- BARTNIK, M
- Venue
- European Heart Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2004-11
- Volume
- 25
- Issue
- 21
- Pages
- 1880-1890
- ISSN
- 0195-668X (ISSN-L)
- OpenAlex
- W1836189764
- Cited by
- 617
- References
- 35
- Citations by year
- 2026: 8 · 2025: 5 · 2024: 7 · 2023: 12 · 2022: 26 · 2021: 15 · 2020: 23 · 2019: 19 · 2018: 19 · 2017: 22 · 2016: 30 · 2015: 36 · 2014: 35 · 2013: 40 · 2012: 52
- FWCI
- 23.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- IRIS UniPA (University of Palermo) (submittedVersion, other-oa)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Keywords
- coronary artery disease, prediabetes, impaired glucose tolerance, diabetes prevalence, oral glucose tolerance test, glucose metabolism, newly diagnosed diabetes, acute coronary syndrome, stable coronary artery disease
- MeSH terms
- Adult, Aged, Blood Glucose, Coronary Artery Disease, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Europe, Female, Glucose Tolerance Test, Humans, Male, Middle Aged, Risk Factors
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