The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

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Items 501–600 of 1,114

1. Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
   Zeyad D. Nassar, Chui Yan Mah, Jonas Dehairs, Ingrid J.G. Burvenich, Swati Irani, Margaret M. Centenera, Madison Helm, Raj Kumar Shrestha, Max V. Moldovan, Anthony Simon Don et al. · 2020 · eLife
2. Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer
   Hikmat A Al‐Ahmadie, Gopa Iyer, Byron Lee, Sasinya N. Scott, Rohit Mehra, Aditya Bagrodia, Emmet Jordan, Sizhi Paul Gao, Ricardo J. Ramirez, Eugene K. Cha et al. · 2016 · Nature Genetics
3. Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression
   Shancheng Ren, Gong‐Hong Wei, Dongbing Liu, Liguo Wang, Yong Hou, Shida Zhu, Lihua Peng, Qin Zhang, Yanbing Cheng, Hong Lin Su et al. · 2017 · European Urology
4. Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets
   Kristen E. Mengwasser, Richard O. Adeyemi, Yumei Leng, Mei Yuk Choi, Connor S. Clairmont, Alan D. D’Andrea, Stephen Joseph Elledge · 2019 · Molecular Cell
5. Cadonilimab, a tetravalent PD-1/CTLA-4 bispecific antibody with trans-binding and enhanced target binding avidity
   Xinghua Pang, Zhaoliang Huang, Tingting Zhong, Peng Zhang, Zhongmin Maxwell Wang, Michelle Xia, Baiyong Li · 2023 · mAbs
6. Tissue-Specific Oncogenic Activity of KRASA146T
   Poulin, Emily J., Bera, Asim K., Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A., Huang, Tannie Q., Morales, Carolina, Yan, Wei, Cook, Joshua et al. · 2019 · Cancer Discovery
7. Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class
   Caleb Rutledge, Jun Kong, Jingjing Gao, David A. Gutman, Lee Cooper, Christina Appin, Yuna Park, Lisa M. Scarpace, Tom Mikkelsen, Mark L. Cohen et al. · 2013 · Clinical Cancer Research
8. Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors
   Aditya Bagrodia, Byron Lee, William Lee, Eugene K. Cha, John P. Sfakianos, Gopa Iyer, Eugene J. Pietzak, Sizhi Paul Gao, Emily Craig Zabor, Irina Ostrovnaya et al. · 2016 · Journal of Clinical Oncology
9. Genetic alterations of m6A regulators predict poorer survival in acute myeloid leukemia
   Chau‐To Kwok, Amy D. Marshall, John E.J. Rasko, Justin J. -L. Wong · 2017 · Journal of Hematology & Oncology
10. UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data
    Shixiang Wang, Yi Xiong, Longfei Zhao, Kai Gu, Yin Li, Fei Zhao, Jianfeng Li, Mingjie Wang, Haitao Wang, Ziyu Tao et al. · 2021 · Bioinformatics
11. Deregulation of Rho GTPases in cancer
    Andrew P. Porter, Alexandra Papaioannou, Angeliki Malliri · 2016 · Small GTPases
12. Dissecting heterogeneity in malignant pleural mesothelioma through histo-molecular gradients for clinical applications
    Yuna Blum, Clément Meiller, Lisa Quetel, Nabila Elarouci, Mira Ayadi, Danisa Tashtanbaeva, Lucile Armenoult, François Montagne, Robin Tranchant, Annie Renier et al. · 2019 · Nature Communications
13. CDKN2A deletion remodels lipid metabolism to prime glioblastoma for ferroptosis
    Jenna K. Minami, Danielle Morrow, Nicholas A. Bayley, Elizabeth G. Fernandez, Jennifer J. Salinas, Christopher Tse, Henan Zhu, Baolong Su, Rhea Plawat, Anthony E. Jones et al. · 2023 · Cancer Cell
14. Cell Model Passports-a hub for clinical, genetic and functional datasets of preclinical cancer models
    van der Meer, Dieudonne, Barthorpe, Syd, Yang, Wanjuan, Lightfoot, Howard, Hall, Caitlin, Gilbert, James, Francies, Hayley E, Garnett, Mathew J · 2019 · Nucleic Acids Research
15. Molecular stratification of metastatic melanoma using gene expression profiling : Prediction of survival outcome and benefit from molecular targeted therapy
    Helena Cirenajwis, Henrik Ekedahl, Martin Lauss, Katja Harbst, Ana Carneiro, Jens Enoksson, Frida Rosengren, Linda Werner Hartman, Therese Törngren, Anders Kvist et al. · 2015 · Oncotarget
16. Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers
    Aritro Nath, Christina Chan · 2016 · Scientific Reports
17. MEF2 transcription factors: developmental regulators and emerging cancer genes
    J. Pon, M. Marra · 2015 · OncoTarget
18. Immune Resistance in Lung Adenocarcinoma
    Μάγδα Σπέλλα, Georgios T. Stathopoulos · 2021 · Cancers
19. Unified classification and risk-stratification in Acute Myeloid Leukemia
    Yanis Tazi, Juan Arango Ossa, Yangyu Zhou, Elsa Bernard, Ian Thomas, Amanda Gilkes, Sylvie D. Freeman, Yoann Pradat, Sean J. Johnson, Robert Kerrin Hills et al. · 2022 · Nature Communications
20. PDK4-dependent hypercatabolism and lactate production of senescent cells promotes cancer malignancy
    Xuefeng Dou, Qiang Fu, Qilai Long, Shuning Liu, Yejun Zou, Da Fu, Qixia Xu, Zhirui Jiang, Xiaohui Ren, Guilong Zhang et al. · 2023 · Nature Metabolism
21. Autonomous biomedical research with an artificial intelligence agent
    Kexin Huang, Serena Zhang, Hanchen Wang, Yuanhao Qu, Yingzhou Lu, Ryan Li, Yusuf Roohani, Lin Qiu, Shiyi Cao, G. L. Li et al. · 2026 · Science
22. A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids
    Below, Christopher R., Kelly, Joanna, Brown, Alexander, Humphries, Jonathan D., Hutton, Colin, Xu, Jingshu, Lee, Brian Y., Cintas, Celia, Zhang, Xiaohong, Hernandez-Gordillo, Victor et al. · 2022 · Nature Materials
23. Hematopoietic lineage distribution and evolutionary dynamics of clonal hematopoiesis
    Arends, Christopher Maximilian, Galan-Sousa, Joel, Hoyer, Kaja, Chan, Willy, Jäger, Marten, Yoshida, Kenichi, Seemann, Ricarda, Noerenberg, Daniel, Waldhueter, Nils, Fleischer-Notter, Helga et al. · 2018 · Leukemia
24. A pan-cancer analysis of the oncogenic role of staphylococcal nuclease domain-containing protein 1 (SND1) in human tumors
    Xiaoteng Cui, Xinxin Zhang, Minghui Liu, Chunyan Zhao, Nan Zhang, Yuanyuan Ren, Chao Su, Wei Zhang, Xiaoming Sun, Jinyan He et al. · 2020 · Genomics
25. Genome-wide Consequences of Deleting Any Single Gene
    Xinchen Teng, Margaret Dayhoff-Brannigan, Wen‐Chih Cheng, Catherine E. Gilbert, Cierra N. Sing, Nicola Laura Diny, Sarah J. Wheelan, Maitreya J. Dunham, Jef D. Boeke, Fernando J. Pineda et al. · 2013 · Molecular Cell
26. Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers
    Arash Salmaninejad, Mohammad Hossein Modarressi, Mehrnaz Pourvahedi, Zahra Golchehre, Ali Hosseini Bereshneh, Nima Rezaei · 2016 · Immunological Investigations
27. Vaccines targeting helper T cells for cancer immunotherapy
    Marit Martina Melssen, Craig Lee Slingluff · 2017 · Current Opinion in Immunology
28. The Role of the Estrogen Pathway in the Tumor Microenvironment
    Natalie J. Rothenberger, Ashwin Somasundaram, Laura P. Stabile · 2018 · International Journal of Molecular Sciences
29. Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer
    Andrew J. Gunderson, Venkatesh Rajamanickam, Cynthia Bui, Brady M. Bernard, Joanna Pucilowska, Carmen Ballesteros‐Merino, Mark Schmidt, Kayla McCarty, Michaela Philips, Brian Piening et al. · 2021 · OncoImmunology
30. BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors
    Timo Reisländer, Emilia Puig Lombardi, Florian J. Groelly, Ana Miar, Manuela Porru, Serena Di Vito, Benjamin Wright, Helen E. Lockstone, Annamaria Biroccio, Adrian Llewellyn Harris et al. · 2019 · Nature Communications
31. The path to the clinic: a comprehensive review on direct KRASG12C inhibitors
    Albert K. Kwan, Gary Anthony Piazza, Adam B. Keeton, Caio A. Leite · 2022 · Journal of Experimental & Clinical Cancer Research
32. Web-TCGA: an online platform for integrated analysis of molecular cancer data sets
    Mario C.-H.K. Deng, Johannes Brägelmann, Joachim Ludwig Schultze, Sven Perner · 2016 · BMC Bioinformatics
33. LncRNA PCAT1 activates AKT and NF-κB signaling in castration-resistant prostate cancer by regulating the PHLPP/FKBP51/IKKα complex
    Zhiqun Shang, Jianpeng Yu, Libin Sun, Jing Tian, Shimiao Zhu, Boya Zhang, Qian Dong, Ning Jiang, Amilcar Flores‐Morales, Chawnshang Chang et al. · 2019 · Nucleic Acids Research
34. PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K
    Malek, Mouhannad, Kielkowska, Anna, Chessa, Tamara, Anderson, Karen E., Barneda, David, Pir, Pınar, Nakanishi, Hiroki, Eguchi, Satoshi, Koizumi, Atsushi, Sasaki, Junko et al. · 2017 · Molecular Cell
35. The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy
    Michael J. Lukey, Kai Su Greene, Jon W. Erickson, Kristin F. Wilson, Richard A. Cerione · 2016 · Nature Communications
36. Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models
    Lillian J. Eichner, Sonja N. Brun, Sébastien Herzig, Nathan P. Young, Stephanie D. Curtis, David B. Shackelford, Maxim Nikolaievich Shokhirev, Mathias Leblanc, Liliana I. Vera, Amanda Hutchins et al. · 2018 · Cell Metabolism
37. Multiomic Analysis of Lung Tumors Defines Pathways Activated in Neuroendocrine Transformation
    Alvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian Ada Zhan, Maysun Hasan, Shweta S. Chavan, Fanli Meng, Fathema Uddin, Parvathy Manoj, Mark T.A. Donoghue, Helen H. Won et al. · 2021 · Cancer Discovery
38. Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements
    Shah, Nakul M., Jang, H. Josh, Liang, Yonghao, Maeng, Ju Heon, Tzeng, Shin-Cheng, Wu, Angela, Basri, Noah L., Qu, Xuan, Fan, Changxu, Li, Amy et al. · 2023 · Nature Genetics
39. An Analysis of the Expression and Association with Immune Cell Infiltration of the cGAS/STING Pathway in Pan-Cancer
    An, Xiang, Zhu, Yuanyuan, Zheng, Tongsen, Wang, Guangyu, Zhang, Minghui, Li, Jiade, Ji, Hongbo, Li, Shijun, Yang, Shucai, Xu, Dandan et al. · 2019 · Molecular Therapy Nucleic Acids
40. Targeting histone lysine methylation in cancer
    John P. McGrath, Patrick Trojer · 2015 · Pharmacology & Therapeutics
41. Comprehensive Genetic Characterization of Human Thyroid Cancer Cell Lines: A Validated Panel for Preclinical Studies
    Iñigo Landa, Nikita V. Pozdeyev, Christopher T. Korch, Laura A. Marlow, Robert C. Smallridge, John Alton Copland, Ying C. Henderson, Stephen Yenzen Lai, Gary L. Clayman, Naoyoshi Onoda et al. · 2019 · Clinical Cancer Research
42. Targeting proprotein convertase subtilisin/kexin type 9 (PCSK9): From bench to bedside
    Bao, Xuhui, Liang, Yongjun, Chang, Hanman, Cai, Tianji, Feng, Baijie, Gordon, Konstantin, Zhu, Yuekun, Shi, Hailian, He, Yundong, Xie, Liyi · 2024 · Signal Transduction and Targeted Therapy
43. Clonal Hematopoiesis in Liquid Biopsy: From Biological Noise to Valuable Clinical Implications
    Hiu Ting Chan, Yoon Ming Chin, Yusuke Nakamura, Siew‐Kee Low · 2020 · Cancers
44. L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling
    Jacquemet, Guillaume, Baghirov, Habib, Georgiadou, Maria, Sihto, Harri, Peuhu, Emilia, Cettour-Janet, Pierre, He, Tao, Perälä, Merja, Kronqvist, Pauliina, Joensuu, Heikki et al. · 2016 · Nature Communications
45. Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
    Xi Feng, Frank Szulzewsky, Alexan I. Yerevanian, Zhihong Chen, David Heinzmann, Rikke Darling Rasmussen, Virginia Alvarez Garcia, Yeonghwan Kim, Bingcheng Wang, Ilaria Tamagno et al. · 2015 · Oncotarget
46. KRAS-related proteins in pancreatic cancer
    Karen M. Mann, Haoqiang Ying, Joseph M. Juan, Nancy A. Jenkins, Neal G. Copeland · 2016 · Pharmacology & Therapeutics
47. SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination
    Waaqo B. Daddacha, Allyson E. Koyen, Amanda J. Bastien, PamelaSara E. Head, Vishal Ramesh Dhere, Geraldine N. Nabeta, Erin C. Connolly, Erica Werner, Matthew Z. Madden, Michele B. Daly et al. · 2017 · Cell Reports
48. mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
    Elodie Villa, Umakant Sahu, Brendan P. O’Hara, Eunus Sheemul Ali, Kathryn A. Helmin, John M. Asara, Peng Gao, Benjamin David Singer, Issam Ben‐Sahra · 2021 · Molecular Cell
49. Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors
    Middlebrooks, Candace D, Banday, A Rouf, Matsuda, Konichi, Udquim, Krizia-Ivana, Onabajo, Olusegun O, Paquin, Ashley, Figueroa, Jonine D, Zhu, Bin, Koutros, Stella, Kubo, Michiaki et al. · 2016 · Nature Genetics
50. Lipocalin 2 expression promotes tumor progression and therapy resistance by inhibiting ferroptosis in colorectal cancer
    Chaudhary, Nazia, Choudhary, Bhagya Shree, Shah, Sanket Girish, Khapare, Nileema, Dwivedi, Nehanjali, Gaikwad, Anagha, Joshi, Neha, Raichanna, Jinsy, Basu, Srikanta, Gurjar, Murari et al. · 2021 · International Journal of Cancer
51. Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma
    Dany Nassar, Mathilde Latil, Bram Boeckx, Diether Lambrechts, Cédric Blanpain · 2015 · Nature Medicine
52. Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma
    Hong Zheng, Wei Dai, Arthur Kwok Leung Cheung, Josephine Mun Yee Ko, Rebecca Kan, Bonnie Wing Yan Wong, Merrin Man‐Long Leong, Mingdan Deng, Tommy Chin Tung Kwok, Jimmy Yu Wai Chan et al. · 2016 · Proceedings of the National Academy of Sciences
53. SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis
    Guihua Wang, Jie Long, Yuan Gao, Weina Zhang, Fei Han, Chuan Shan Xu, Li Sun, Shun-Chin Yang, Jingqin Lan, Zhenlin Hou et al. · 2019 · Nature Cell Biology
54. Phase II Study of the WEE1 Inhibitor Adavosertib in Recurrent Uterine Serous Carcinoma
    Joyce F. Liu, Niya Xiong, Susana M. Campos, Alexi A. Wright, Carolyn N. Krasner, Susan Schumer, Neil Stuart Horowitz, Jennifer Taylor Veneris, Nabihah Tayob, Stephanie Morrissey et al. · 2021 · Journal of Clinical Oncology
55. Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations
    Jennifer A. Oberg, Julia Glade Bender, Maria Luisa Sulis, Danielle Pendrick, Anthony N. Sireci, Susan Jean Hsiao, Andrew T. Turk, Filemon S. Dela Cruz, Hanina H. Hibshoosh, Helen Elaine Remotti et al. · 2016 · Genome Medicine
56. Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy
    Lu Wang, Zibo Zhao, Patrick A. Ozark, Damiano Fantini, Stacy A. Marshall, Emily Jane Rendleman, Kira Cozzolino, Nundia Louis, Xingyao He, Marc A. Morgan et al. · 2018 · Nature Medicine
57. The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance
    Fei Han, Chien‐Feng Li, Zhen Cai, Xian Zhang, Guoxiang Jin, Wei-Na Zhang, Chuan Shan Xu, Chi‐Yun Wang, John Kenneth Morrow, Shuxing Zhang et al. · 2018 · Nature Communications
58. Whole-genome sequencing of acral melanoma reveals genomic complexity and diversity
    Felicity Newell, James S. Wilmott, Peter A. Johansson, Kátia Nones, Venkateswar Addala, Pamela Mukhopadhyay, Natasa Broit, Carol M. Amato, Robert J. Van Gulick, Stephen H. Kazakoff et al. · 2020 · Nature Communications
59. Glutaminase inhibition impairs CD8 T cell activation in STK11-/Lkb1-deficient lung cancer
    Sarah A. Best, Patrick M. Gubser, Shalini Sethumadhavan, Ariena J. Kersbergen, Yashira L. Negrón Abril, Joshua E. Goldford, Katherine Sellers, Waruni Abeysekera, Alexandra L. Garnham, Jackson A. McDonald et al. · 2022 · Cell Metabolism
60. Driver mutations of cancer epigenomes
    David M. Roy, Logan A. Walsh, Timothy An-thy Chan · 2014 · Protein & Cell
61. In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift
    John J. Halliday, Karim Y. Helmy, Siobhan S. Pattwell, Kenneth L. Pitter, Quincey C. LaPlant, Tatsuya Ozawa, Eric C. Holland · 2014 · Proceedings of the National Academy of Sciences
62. La FAM fatale: USP9X in development and disease
    Mariyam Murtaza, Lachlan A. Jolly, Jozef Gécz, Stephen A. Wood · 2015 · Cellular and Molecular Life Sciences
63. Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism
    Paul-Joseph P. Aspuria, Sophia Y. Lunt, Leif Väremo, Laurent Vergnes, Maricel C. Gozo, Jessica A. Beach, Brenda C. Salumbides, Karen Reue, W. Ruprecht Wiedemeyer, Jens Nielsen et al. · 2014 · Cancer & Metabolism
64. DriverDBv3: a multi-omics database for cancer driver gene research
    Shu‐Hsuan Liu, Pei-Chun Shen, Chen‐Yang Chen, An-Ni Hsu, Yi-Chun Cho, Yo-Liang Lai, George T.Y. Chen, Chia‐Yang Li, Shu‐Chi Wang, Ming Chen et al. · 2019 · Nucleic Acids Research
65. Liquid biopsy in central nervous system metastases: a RANO review and proposals for clinical applications
    Boire, Adrienne, Brandsma, Dieta, Brastianos, Priscilla K, Le Rhun, Emilie, Ahluwalia, Manmeet, Junck, Larry, Glantz, Michael, Groves, Morris D, Lee, Eudocia Q, Lin, Nancy et al. · 2019 · Neuro-Oncology
66. POLE exonuclease domain mutation predicts long progression-free survival in grade 3 endometrioid carcinoma of the endometrium
    Bo Meng, Lien N. Hoang, John B. McIntyre, Máire A. Duggan, Gregg S Nelson, Cheng‐Han Lee, Martin Köbel · 2014 · Gynecologic Oncology
67. A new tumor suppressor role for the Notch pathway in bladder cancer
    Theodoros N Rampias, Paraskevi Vgenopoulou, Margaritis Avgeris, Alexander Polyzos, KONSTANTINOS G. STRAVODIMOS, Christos Valavanis, Andreas Scorilas, Apostolos Klinakis · 2014 · Nature Medicine
68. The prognostic value of TP53 and its correlation with EGFR mutation in advanced non-small cell lung cancer, an analysis based on cBioPortal data base
    Xiao‐Dong Jiao, Bao‐Dong Qin, Pu You, Jian Qiang Cai, Yuan‐Sheng Zang · 2018 · Lung Cancer
69. NRF2 Activation in Cancer: From DNA to Protein
    Erica W. Cloer, Dennis Goldfarb, Travis Parke Schrank, Bernard E. Weissman, Michael B. Major · 2019 · Cancer Research
70. EZH2 negatively regulates PD-L1 expression in hepatocellular carcinoma
    Gang Xiao, Li-Lian Jin, Chaoqun Liu, Yongchun Wang, Ya-Ming Meng, Zhongguo Zhou, Jing Chen, Xing-Juan Yu, Yaojun Zhang, Jing Xu et al. · 2019 · Journal for ImmunoTherapy of Cancer
71. Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma
    Arun M. Unni, William Wirt Lockwood, Kreshnik Zejnullahu, Shih-Queen Lee-Lin, HAROLD E. VARMUS · 2015 · eLife
72. Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
    Ying‐Bei Chen, Jianing Xu, Anders J. Skanderup, Yiyu Dong, Angela Rose Brannon, Lu Wang, Helen H. Won, Patricia I. Wang, Gouri J. Nanjangud, Achim A. Jungbluth et al. · 2016 · Nature Communications
73. Checkpoint Blockade Reverses Anergy in IL-13Rα2 Humanized scFv-Based CAR T Cells to Treat Murine and Canine Gliomas
    Yibo Yin, Alina C. Boesteanu, Zev A. Binder, Chong Bing Xu, Reiss A. Reid, Jesse L. Rodriguez, Danielle R. Cook, Radhika Thokala, Kristin Blouch, Bevin McGettigan-Croce et al. · 2018 · Molecular Therapy — Oncolytics
74. Application of weighted gene co-expression network analysis to identify key modules and hub genes in oral squamous cell carcinoma tumorigenesis
    Xiaoqi Zhang, Hao Feng, Ziyu Li, Dongfang Li, Shanshan Liu, Haiyun Huang, Minqi Li · 2018 · OncoTargets and Therapy
75. A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily
    Anil Korkut, Sobia Zaidi, Rupa S. Kanchi, Shuyun Rao, Nancy R. Gough, André Schultz, Xubin Li, Philip L. Lorenzi, Ashton C. Berger, Gordon Robertson et al. · 2018 · Cell Systems
76. Tumor Heterogeneity Correlates with Less Immune Response and Worse Survival in Breast Cancer Patients
    Kerry-Ann McDonald, Tsutomu Kawaguchi, Qianya Qi, Xuan Peng, Mariko Asaoka, Jessica S. Young, Mateusz Opyrchal, Li Yan, Santosh Kumar Patnaik, Eigo Otsuji et al. · 2019 · Annals of Surgical Oncology
77. Renal Cell Carcinoma as a Metabolic Disease: An Update on Main Pathways, Potential Biomarkers, and Therapeutic Targets
    Nicola Antonio di Meo, Francesco M. Lasorsa, Monica Rutigliano, Davide Loizzo, Matteo Ferro, Alessandro Stella, Cinzia Bizzoca, Leonardo Vincenti, Savio Domenico Pandolfo, Riccardo Autorino B et al. · 2022 · International Journal of Molecular Sciences
78. Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination
    Cecilia Herráiz, Fernando Calvo, Pahini Pandya, Gaia Cantelli, Irene Rodríguez‐Hernández, José Luis Orgaz, NaRa Kang, Tinghine Chu, Erik A. Sahai, Victoria Sanz‐Moreno · 2015 · JNCI Journal of the National Cancer Institute
79. Molecular classification and diagnostics of upper urinary tract urothelial carcinoma
    Yoichi Robertus Fujii, Yusuke Sato, Hiromichi Suzuki, Nobuyuki Kakiuchi, Tetsuichi Yoshizato, Andrew Thomas Lenis, Shigekatsu Maekawa, Akira Yokoyama, Yasuhide Takeuchi, Yoshikage Inoue et al. · 2021 · Cancer Cell
80. Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
    Emily Jane Kay, Karla Paterson, Carla Riera‐Domingo, David P. Sumpton, J. Henry M. Däbritz, Saverio Tardito, Claudia Boldrini, Juan Ramon Hernandez-Fernaud, Dimitris Athineos, Sandeep Dhayade et al. · 2022 · Nature Metabolism
81. The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer
    Brock J. Sishc, Anthony J. Davis · 2017 · Cancers
82. Triple-Negative Breast Cancer: Molecular Subtypes and New Targets for Therapy
    Brian David Lehmann, Jennifer A. Pietenpol, Antoinette R. Tan · 2015 · American Society of Clinical Oncology Educational Book
83. Integration and Analysis of CPTAC Proteomics Data in the Context of Cancer Genomics in the cBioPortal
    Pamela Wu, Zachary J. Heins, James Muller, Lizabeth Katsnelson, Ino de Bruijn, Adam A. Abeshouse, Nikolaus D. Schultz, David Fenyö, Jianjiong Gao · 2019 · Molecular & Cellular Proteomics
84. Comprehensive Genetic Landscape of Uveal Melanoma by Whole-Genome Sequencing
    Béryl Royer‐Bertrand, Matteo Torsello, Donata Rimoldi, Ikram El Zaoui, Katarina Vizar Cisarova, Rosanna Pescini Gobert, Franck Raynaud, Léonidas Zografos, Ann Schalenbourg, Daniel E. Speiser et al. · 2016 · The American Journal of Human Genetics
85. TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis
    Pilar M. Domínguez, Hussein Ghamlouch, Wojciech Rosikiewicz, Parveen Kumar, Wendy Béguelin, Lorena Fontán, Martín A. Rivas, Patrycja Pawlikowska, Marine Armand, Enguerran Mouly et al. · 2018 · Cancer Discovery
86. Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy
    Victoria H. Wu, Huwate Yeerna, Nijiro Nohata, Joshua Chiou, Olivier Harismendy, Francesco Raimondi, Asuka Inoue, Robert B. Russell, Pablo Tamayo, Jorge Silvio Gutkind · 2019 · Journal of Biological Chemistry
87. Genetic alterations of histone lysine methyltransferases and their significance in breast cancer
    Lanxin Liu, Sarah Kimball, Hui Liu, Andreana Holowatyj, Zeng-Quan Yang · 2014 · Oncotarget
88. Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma
    Chiara Ambrogio, Gonzalo Goméz-López, Mattia Falcone, August Vidal, Ernest Nadal, Nicola Crosetto, Rafael B Blasco, Pablo J. Fernández-Marcos, Montse Sánchez‐Céspedes, Xiaomei Ren et al. · 2016 · Nature Medicine
89. Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms
    Marco Bezzi, Nina Seitzer, Tomoki Ishikawa, Markus Reschke, Ming Chen, Guocan Wang, Caitlin Mitchell, Christopher Ng, Jesse Mae Katon, Andrea Lunardi et al. · 2018 · Nature Medicine
90. Re-definition of claudin-low as a breast cancer phenotype
    Christian Fougner, Helga Bergholtz, Jens Henrik Norum, Thérese Sørlie · 2020 · Nature Communications
91. Midkine activation of CD8+ T cells establishes a neuron–immune–cancer axis responsible for low-grade glioma growth
    Xiaofan Guo, Yuan Pan, Min Xiong, Shilpa Sanapala, Corina Anastasaki, Olivia M. Cobb, Sonika M Dahiya, David H. Gutmann · 2020 · Nature Communications
92. Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
    Jay K. Mandula, Shiun Chang, Eslam T. Mohamed, Rachel Jimenez, Rosa A. Sierra-Mondragon, Darwin Chang, Alyssa Obermayer, Carlos Moran Segura, Satyajit Das, Julio Angel Vázquez-Martínez et al. · 2022 · Cancer Cell
93. Acetyl-CoA regulates lipid metabolism and histone acetylation modification in cancer
    Weijing He, Qingguo Li, Xinxiang Li · 2022 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
94. RAS: Striking at the Core of the Oncogenic Circuitry
    Gimple, Ryan C., Wang, Xiuxing · 2019 · Frontiers in Oncology
95. Polymerase ɛ ( POLE ) mutations in endometrial cancer: Clinical outcomes and implications for L ynch syndrome testing
    Caroline C. Billingsley, David E. Cohn, David Gardner Mutch, Julie A. Stephens, Adrian A. Suarez, Paul J. Goodfellow · 2014 · Cancer
96. COMPASS Ascending: Emerging clues regarding the roles of MLL3/KMT2C and MLL2/KMT2D proteins in cancer
    Richard J. Fagan, Andrew K. Dingwall · 2019 · Cancer Letters
97. Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma
    Lihong Wang-Bishop, Mohamed Wehbe, Daniel Shae, Jamaal L. James, Benjamin C. Hacker, Kyle M. Garland, Plamen P. Chistov, Marjan Rafat, Justin Micah Balko, John T. Wilson · 2020 · Journal for ImmunoTherapy of Cancer
98. SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis
    Xun Shangguan, Jianli He, Zehua Ma, Weiwei Zhang, Yiyi Ji, Kai Shen, Zhiying Yue, Wenyu Li, Zhixiang Xin, Quan Zheng et al. · 2021 · Nature Communications
99. Regulatory T cells promote cancer immune-escape through integrin αvβ8-mediated TGF-β activation
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