The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

Cited by (1,114)

Items 401–500 of 1,114

1. Patterns of ribosomal protein expression specify normal and malignant human cells
   Joao C. Guimaraes, Mihaela Zavolan · 2016 · Genome biology
2. Genomic Analysis of Tumor Microenvironment Immune Types across 14 Solid Cancer Types: Immunotherapeutic Implications
   Yu‐Pei Chen, Yu Xin Zhang, Jia-Wei Lv, Ying-Qin Li, Yaqin Wang, Qing-Mei He, Xiao-Jing Yang, Ying Hao Sun, Yan‐Ping Mao, Jing‐Ping Yun et al. · 2017 · Theranostics
3. Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets
   Nacev, Benjamin A., Sanchez-Vega, Francisco, Smith, Shaleigh A., Antonescu, Cristina R., Rosenbaum, Evan, Shi, Hongyu, Tang, Cerise, Socci, Nicholas D., Rana, Satshil, Gularte-Mérida, Rodrigo et al. · 2022 · Nature Communications
4. NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling
   Sudhir Chowdhry, Ciro Zanca, Utkrisht Rajkumar, Tomoyuki Koga, Yarui Diao, Ramya Raviram, Feng Liu, Kristen M. Turner, Huijun Yang, Elizabeth Brunk et al. · 2019 · Nature
5. Mutations in TSC1, TSC2, and MTOR are associated with response to rapalogs in patients with metastatic Renal Cell Carcinoma
   D. Kwiatkowski, T. Choueiri, A. Fay, B. Rini, A. Thorner, G. de Velasco, M. Tyburczy, L. Hamieh, L. Albigès, N. Agarwal et al. · 2016 · Clinical Cancer Research
6. β-Catenin induces transcriptional expression of PD-L1 to promote glioblastoma immune evasion
   Linyong Du, Jong‐Ho Lee, Hongfei Jiang, Chengde Wang, Silu Wang, Zhihong Zheng, Fei Shao, Daqian Xu, Yan Xia, Jing Li et al. · 2020 · The Journal of Experimental Medicine
7. Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: A large-scale meta-analysis
   Abhishek Dinkarnath Garg, Dirk De Ruysscher, Patrizia Agostinis · 2015 · OncoImmunology
8. Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
   Junfeng Bi, Taka-Aki Ichu, Ciro Zanca, Huijun Yang, Wei Zhang, Yuchao Gu, Sudhir Chowdhry, Alex Reed, Shiro Ikegami, Kristen M. Turner et al. · 2019 · Cell Metabolism
9. Exploiting interconnected synthetic lethal interactions between PARP inhibition and cancer cell reversible senescence
   Fleury, Hubert, Malaquin, Nicolas, Tu, Véronique, Gilbert, Sophie, Martinez, Aurélie, Olivier, Marc-Alexandre, Sauriol, Skye Alexandre, Communal, Laudine, Leclerc-Desaulniers, Kim, Carmona, Euridice et al. · 2019 · Nature Communications
10. De novo and salvage purine synthesis pathways across tissues and tumors
    Tran, Diem H., Kim, Dohun, Kesavan, Rushendhiran, Brown, Harrison, Dey, Trishna, Soflaee, Mona Hoseini, Vu, Hieu S., Tasdogan, Alpaslan, Guo, Jason, Bezwada, Divya et al. · 2024 · Cell
11. Genomic and phenotypic characterization of a broad panel of patient-derived xenografts reflects the diversity of glioblastoma
    Vaubel, Rachael A., Tian, Shulan, Remonde, Dioval, Schroeder, Mark A., Mladek, Ann C., Kitange, Gaspar J., Caron, Alissa, Kollmeyer, Thomas M., Grove, Rebecca, Peng, Sen et al. · 2020 · Clinical Cancer Research
12. The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies
    Zenggang Li, Andrei A. Ivanov, Rina Su, Valentina González-Pecchi, Qi Qi, Songlin Liu, Philip J. Webber, Elizabeth A. McMillan, Lauren E. Rusnak, Cau Pham et al. · 2017 · Nature Communications
13. Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer
    Daniel G. Stover, Heather Anne Parsons, Gavin Ha, Samuel S. Freeman, William Thomas Barry, Hao Guo, Atish Dipankar Choudhury, Gregory Gydush, Sarah C. Reed, Justin Rhoades et al. · 2018 · Journal of Clinical Oncology
14. Proteome Profiling of Cancer-Associated Fibroblasts Identifies Novel Proinflammatory Signatures and Prognostic Markers for Colorectal Cancer
    Sofía Torres, Rubén A. Bartolomé, Marta L. Mendes, Rodrigo Barderas, María Jesús Fernández‐Aceñero, Alberto Peláez‐García, Cristina Peña, María F. López-Lucendo, Roi Villar-Vázquez, Antonio Garcı́a de Herreros et al. · 2013 · Clinical Cancer Research
15. Extracellular Glutathione Peroxidase GPx3 and Its Role in Cancer
    Caroline A. Chang, Beth L. Worley, Rébécca Phaëton, Nadine Hempel · 2020 · Cancers
16. TP63-mediated enhancer reprogramming drives the squamous subtype of pancreatic ductal adenocarcinoma
    Somerville, Tim D.D., Xu, Yali, Miyabayashi, Koji, Tiriac, Hervé, Cleary, Cristian R., Maia-Silva, Diogo, Milazzo, Joseph P., Tuveson, David A., Vakoc, Christopher R. · 2018 · Cell Reports
17. Chemoresistance and targeted therapies in ovarian and endometrial cancers
    Kevin Brasseur, Nicolas Y. Gévry, Éric Asselin · 2016 · Oncotarget
18. SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis
    Xiaolong Tang, Lei Shi, Ni Xie, Zuojun Liu, Minxian Qian, Fanbiao Meng, Qing-Yang Xu, Mingyan Zhou, Xinyue Cao, Wei‐Guo Zhu et al. · 2017 · Nature Communications
19. SOX4: The unappreciated oncogene
    Carlos S. Moreno · 2019 · Seminars in Cancer Biology
20. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment
    Stefanie Riesenberg, Angela Groetchen, Robert Siddaway, Tobias Bald, Julia Reinhardt, Denise Smorra, Judith D. Sirokay, Marcel Renn, Bengt Phung, Pia Aymans et al. · 2015 · Nature Communications
21. PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition
    Pau Castel, Haley Ellis, Ružica Bago, Eneda Toska, Pedram Razavi, F. Javier Carmona, Srinivasaraghavan Kannan, Chandra Shekhar Verma, Maura N. Dickler, Sarat Chandarlapaty et al. · 2016 · Cancer Cell
22. Maximising the potential of AKT inhibitors as anti-cancer treatments
    Jessica S. Brown, Udai Banerji · 2016 · Pharmacology & Therapeutics
23. Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Associated Fibroblast–Driven Nutritional Support and Immunosuppression
    Ralph Francescone, Debora Barbosa Vendramini Costa, Janusz Franco‐Barraza, Jessica Wagner, Alexander Muir, Allison N. Lau, Linara Gabitova, Tatiana Pazina, Sapna Gupta, Tiffany Luong et al. · 2020 · Cancer Discovery
24. Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation
    Cuartero, Sergi, Weiss, Felix D., Dharmalingam, Gopuraja, Guo, Ya, Ing-Simmons, Elizabeth, Masella, Silvia, Robles-Rebollo, Irene, Xiao, Xiaolin, Wang, Yi-Fang, Barozzi, Iros et al. · 2018 · Nature Immunology
25. IDH1 and IDH2 mutations as novel therapeutic targets: current perspectives
    de Botton, Stephane, Mondesir, Johanna, Willekens, Christophe, Touat, Mehdi · 2016 · Journal of Blood Medicine
26. Dual loss of the SWI / SNF complex ATPases SMARCA4 / BRG1 and SMARCA2 / BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type
    Anthony Nicholas Karnezis, Yemin Wang, Pilar Ramos, William P.D. Hendricks, Esther Oliva, Emanuela D′Angelo, Jaime Prat, Marisa R. Nucci, Torsten O. Nielsen, Christine Chow et al. · 2015 · The Journal of Pathology
27. A novel gene expression-based prognostic scoring system to predict survival in gastric cancer
    Pin Wang, Yunshan Wang, Bo Hang, Xiaoping Zou, Jian‐Hua Mao · 2016 · Oncotarget
28. Estrogen Receptor Signaling in Breast Cancer
    Paulina Anna Miziak, Marzena Teresa Baran, Ewa Błaszczak, Alicja Przybyszewska-Podstawka, Joanna Kałafut, Jolanta Smok-Kalwat, Magdalena Dmoszyńska‐Graniczka, Michał Kiełbus, Andrzej Stepulak · 2023 · Cancers
29. Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy
    Samstein, Robert M., Krishna, Chirag, Ma, Xiaoxiao, Pei, Xin, Lee, Ken-Wing, Makarov, Vladimir, Kuo, Fengshen, Chung, Jonathan, Srivastava, Raghvendra M., Purohit, Tanaya A. et al. · 2020 · Nature Cancer
30. Genomic landscapes of breast fibroepithelial tumors
    Jing Ying Tan, Choon Kiat Ong, Weng Khong Lim, Cedric Chuan Young Ng, Aye Aye Thike, Ley Moy Ng, Vikneswari Rajasegaran, Swe Swe Myint, Sanjanaa Nagarajan, Saranya Thangaraju et al. · 2015 · Nature Genetics
31. Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors
    Matthias Lechner, Garrett Michael Frampton, Tim R. Fenton, Andrew Feber, Gary A. Palmer, Amrita Jay, Nischalan Pillay, Martin David Forster, Maureen T. Cronin, Doron Lipson et al. · 2013 · Genome Medicine
32. Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer
    Francesco Crea, Akira Watahiki, Luca Quagliata, Hui Xue, Larissa A. Pikor, Abhijit Parolia, Yuwei Wang, Dong Lin, Wan L. Lam, William L. Farrar et al. · 2014 · Oncotarget
33. The PI3K/Akt/mTOR pathway in ovarian cancer: therapeutic opportunities and challenges
    Bianca Cheaib, Aurélie Auguste, Alexandra F. Leary · 2015 · 癌症：英文版
34. The NF1 gene in tumor syndromes and melanoma
    Maija H. Kiuru, Klaus Johannes BUSAM · 2017 · Laboratory Investigation
35. 3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets
    Jianjiong Gao, Matthew T. Chang, Hannah C. Johnsen, Sizhi Paul Gao, Brooke E. Sylvester, Selçuk Onur Sümer, Hongxin Zhang, David B. Solit, Barry S. Taylor, Nikolaus D. Schultz et al. · 2017 · Genome Medicine
36. Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer
    Hanghang Zhang, Somnath Pandey, Meghan E. Travers, Hongxing Sun, George C. Morton, Jozef Madžo, Woonbok Chung, Jittasak Khowsathit, Óscar Cano Pérez, Carlos Alberto Barrero et al. · 2018 · Cell
37. The RNA Methyltransferase NSUN2 and Its Potential Roles in Cancer
    Anitha Chellamuthu, Steven G. Gray · 2020 · Cells
38. Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
    Best, Sarah A., De Souza, David P., Kersbergen, Ariena, Policheni, Antonia N., Dayalan, Saravanan, Tull, Dedreia, Rathi, Vivek, Gray, Daniel H., Ritchie, Matthew E., McConville, Malcolm J. et al. · 2018 · Cell Metabolism
39. KEAP1-driven co-mutations in lung adenocarcinoma unresponsive to immunotherapy despite high tumor mutational burden
    Daniele Marinelli, Marco Mazzotta, Stefano Scalera, Irene Terrenato, Francesca Sperati, L. D'Ambrosio, Matteo Pallocca, Giacomo Corleone, Eriseld Krasniqi, Laura Pizzuti et al. · 2020 · Annals of Oncology
40. Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2
    Scott A. Foster, Daniel M. Whalen, Ayşegül Özen, Matthew J. Wongchenko, Jianping Yin, Ivana Yen, Gabriele Schaefer, John D. Mayfield, Juliann Chmielecki, Philip J. Stephens et al. · 2016 · Cancer Cell
41. UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis
    Xiongjun Wang, Ruilong Liu, Wencheng Zhu, Huiying Chu, Hua Tao Yu, Ping Wei, Xueyuan Wu, Hongwen Zhu, Hong Gao, Ji Liang et al. · 2019 · Nature
42. USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation
    Sunbin Ling, Qiaonan Shan, Qifan Zhan, Qianwei Ye, Peng Liu, Shengjun Xu, Xin He, Jian Ma, Jiajia Xiang, Guangjiang Jiang et al. · 2019 · Gut
43. Immune landscapes predict chemotherapy resistance and immunotherapy response in acute myeloid leukemia
    Jayakumar Narayanan Vadakekolathu, Mark David Minden, Tressa Hood, SE Church, Stephen Reeder, Heidi Altmann, Amy H. Sullivan, Elena Viboch, Tasleema Patel, Narmin Ibrahimova et al. · 2020 · Science Translational Medicine
44. Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer
    Vanharanta, Sakari, Shu, Weiping, Brenet, Fabienne, Hakimi, A Ari, Heguy, Adriana, Viale, Agnes, Reuter, Victor E, Hsieh, James J-D, Scandura, Joseph M, Massagué, Joan · 2013 · Nature Medicine
45. Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer
    Puca, Loredana, Gavyert, Katie, Sailer, Verena, Conteduca, Vincenza, Dardenne, Etienne, Sigouros, Michael, Isse, Kumiko, Kearney, Megan, Vosoughi, Aram, Fernandez, Luisa et al. · 2019 · Science Translational Medicine
46. SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression
    Wenjian Gan, Xiangpeng Dai, Andrea Lunardi, Zhen Li, Hiroyuki Inuzuka, Pengda Liu, Shoreh Varmeh, Jinfang Zhang, Liang Cheng C, Yin Sun et al. · 2015 · Molecular Cell
47. Mutation-Specific RAS Oncogenicity Explains NRAS Codon 61 Selection in Melanoma
    Christin Elizabeth Burd, Wenjin Liu, Minh V. Huynh, Meriam A. Waqas, James E. Gillahan, Kelly S. Clark, Kailing Fu, Brit L. Martin, William R. Jeck, George P. Souroullas et al. · 2014 · Cancer Discovery
48. Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression
    Jing-Wen Shih, Wei-Fan Chiang, Alexander T.H. Wu, Ming–Heng Wu, Ling‐Yu Wang, Yen‐Ling Yu, Yu‐Wen Hung, Wen‐Chang Wang, Cheng-Ying Chu, Chiu-Lien Hung et al. · 2017 · Nature Communications
49. Tumor Genetic Analyses of Patients with Metastatic Renal Cell Carcinoma and Extended Benefit from mTOR Inhibitor Therapy
    Martin Henner Voss, A. Ari Hakimi, Can G. Pham, Angela Rose Brannon, Ying‐Bei Chen, Luis F. Cunha, Oğuz Akın, Han Liu, Shugaku Takeda, Sasinya N. Scott et al. · 2014 · Clinical Cancer Research
50. Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression
    Juan Liu, Cen Zhang, Yuhan Zhao, Xuetian Yue, Hao Wu, SHAN HU HUANG, James Chen, Kyle Tomsky, Haiyang Xie, Christen A. Khella et al. · 2017 · Nature Communications
51. Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers
    Yan Zhang, Dayong Zheng, Ting Zhou, Haiping Song, Mohit M. Hulsurkar, Ning Su, Ying Liu, Zheng Wang, Long Shao, Michael Ittmann et al. · 2018 · Nature Communications
52. An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation
    Souroullas, George P, Jeck, William R, Parker, Joel S, Simon, Jeremy M, Liu, Jie-Yu, Paulk, Joshiawa, Xiong, Jessie, Clark, Kelly S, Fedoriw, Yuri, Qi, Jun et al. · 2016 · Nature Medicine
53. Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence
    Fletcher-Sananikone, Eliot, Kanji, Suman, Tomimatsu, Nozomi, Di Cristofaro, Luis Fernando Macedo, Kollipara, Rahul K., Saha, Debabrata, Floyd, John R., Sung, Patrick, Hromas, Robert, Burns, Terry C. et al. · 2021 · Cancer Research
54. Genetic hallmarks of recurrent/metastatic adenoid cystic carcinoma
    Allen S. Ho, Angelica Ochoa, Gowtham Jayakumaran, Ahmet Zehir, Cristina Valero, Justin Tepe, Vladimir Makarov, Martin G. Dalin, Jie He, Mark Bailey et al. · 2019 · Journal of Clinical Investigation
55. Comprehensive Benchmarking and Integration of Tumor Microenvironment Cell Estimation Methods
    Alejandro Jiménez-Sánchez, Oliver M. Cast, Martin L. Miller · 2019 · Cancer Research
56. Tight junction proteins: From barrier to tumorigenesis
    Edwin Aaron Runkle, David Mu · 2013 · Cancer Letters
57. The metabolic co-regulator PGC1α suppresses prostate cancer metastasis
    Verónica Torrano, Lorea Valcárcel-Jiménez, Ana R. Cortázar, Xiaojing Liu, Jelena Urosevic, Mireia Castillo-Martín, Sonia Fernández‐Ruiz, Giampaolo Morciano, Alfredo Caro‐Maldonado, Marc Guiu et al. · 2016 · Nature Cell Biology
58. The Tumor Immune Microenvironment Drives a Prognostic Relevance That Correlates with Bladder Cancer Subtypes
    Carolin Pfannstiel, Pamela L. Strissel, Katherine Bakshian Chiappinelli, Danijel Sikic, Sven Wach, Ralph Markus Wirtz, Adrian Wullweber, Helge W. Taubert, Johannes Breyer, Wolfgang Otto et al. · 2019 · Cancer Immunology Research
59. A Critical Role for Fas-Mediated Off-Target Tumor Killing in T-cell Immunotherapy
    Ranjan Upadhyay, Jonathan Boiarsky, Gvantsa Pantsulaia, Judit Svensson‐Arvelund, Matthew Junda Lin, Aleksandra Wroblewska, Sherry Bhalla, Nathalie Scholler, Adrian I Bot, John M. Rossi et al. · 2021 · Cancer Discovery
60. Replication Gaps Underlie BRCA Deficiency and Therapy Response
    Nicholas J. Panzarino, John J. Krais, Min Peng, Michelle Mosqueda, Sumeet Nayak, Samuel Bond, Jennifer A. Calvo, Ke Cong, Mihir B. Doshi, Matt Bere et al. · 2020 · Cancer Research
61. CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics
    Augustin Luna, Fathi Elloumi, Sudhir Varma, Yanghsin Wang, Vinodh N. Rajapakse, Mirit I. Aladjem, Jacques Robert, Chris Sander, Yves G. Pommier, William C. Reinhold · 2020 · Nucleic Acids Research
62. IFNα Potentiates Anti–PD-1 Efficacy by Remodeling Glucose Metabolism in the Hepatocellular Carcinoma Microenvironment
    Bo Hu, Mincheng Yu, Xiaolu Ma, Jialei Sun, Chenglong Liu, Chunyan Wang, Suiyi Wu, Pei‐Yao Fu, Zhen Fan Yang, Yungang He et al. · 2022 · Cancer Discovery
63. The origins and genetic interactions of KRAS mutations are allele- and tissue-specific
    Cook, Joshua H., Melloni, Giorgio E. M., Gulhan, Doga C., Park, Peter J., Haigis, Kevin M. · 2021 · Nature Communications
64. PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression
    Kelly Chiang, Agnieszka E. Zielinska, Abeer M. Shaaban, María Pilar Sánchez-Bailón, James Jarrold, Thomas L. Clarke, Jingxian Zhang, Adele Francis, J. Louise Jones, Sally Smith et al. · 2017 · Cell Reports
65. A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma
    Brett William Stringer, Bryan W. Day, Rochelle C. J. D’Souza, Paul R. Jamieson, Kathleen S. Ensbey, Zara C. Bruce, Yi Chieh Lim, Kate Goasdoué, Carolin Offenhäuser, Seçkin Akgül et al. · 2019 · Scientific Reports
66. Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation
    Wei Xie, Lodoe Lama, Carolina Adura, Daisuke Tomita, Joseph Fraser Glickman, Thomas Tuschl, Dinshaw J. Patel · 2019 · Proceedings of the National Academy of Sciences
67. Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy
    D. Forte, M. García-Fernández, Abel Sánchez-Aguilera, V. Stavropoulou, C. Fielding, D. Martı́n-Pérez, J. López, Ana S. H. Costa, Laura Tronci, Efterpi Nikitopoulou et al. · 2020 · Cell Metabolism
68. Cancer gene mutation frequencies for the U.S. population
    Gaurav Mendiratta, Eugene Ke, Meraj Aziz, David Liarakos, Melinda M. Tong, Edward C. Stites · 2021 · Nature Communications
69. Cyclin E1 Deregulation Occurs Early in Secretory Cell Transformation to Promote Formation of Fallopian Tube–Derived High-Grade Serous Ovarian Cancers
    Alison M. Karst, Paul Jones, Natalie Vena, Azra Hadi Ligon, Joyce F. Liu, Michelle S. Hirsch, Dariush Etemadmoghadam, David D.L. Bowtell, Ronny Drapkin · 2013 · Cancer Research
70. Machine learning and feature selection for drug response prediction in precision oncology applications
    Mehreen Ali, Tero A. Aittokallio · 2018 · Biophysical Reviews
71. Integrated analysis of patient samples identifies biomarkers for venetoclax efficacy and combination strategies in acute myeloid leukemia
    Haijiao Zhang, Yusuke Nakauchi, Thomas Köhnke, Melissa Stafford, Daniel Bottomly, Rozario Thomas, Beth Wilmot, Shannon K. McWeeney, Ravindra Majeti, Jeffrey W Tyner · 2020 · Nature Cancer
72. A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding
    Qilai Huang, Thomas Whitington, Ping Hui Gao, Johan Lindberg, Yuehong Yang, Jielin Sun, Marja‐Riitta Väisänen, Robert Szulkin, Matti Annala, Jian Yan et al. · 2014 · Nature Genetics
73. Higher‐order oligomerization promotes localization of SPOP to liquid nuclear speckles
    Melissa R. Marzahn, Suresh Marada, Jihun Lee, Amanda Nourse, Sophia A. Kenrick, Huaying Zhao, Gili Ben‐Nissan, Regina‐Maria Kolaitis, Jennifer L. Peters, Stanley B Pounds et al. · 2016 · The EMBO Journal
74. Alternative preprocessing of RNA-Sequencing data in The Cancer Genome Atlas leads to improved analysis results
    Moom Rahman Roosan, Laurie K. Jackson, William Evan Johnson, Dean Y. Li, Andrea H. Bild, Stephen Piccolo · 2015 · Bioinformatics
75. Molecular Pathways: Isocitrate Dehydrogenase Mutations in Cancer
    Owen Clark, Katharine E. Yen, Ingo K. Mellinghoff · 2016 · Clinical Cancer Research
76. pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
    Jianping Guo, Abhishek A. Chakraborty, Pengda Liu, Wenjian Gan, Xingnan Zheng, Hiroyuki Inuzuka, Bin Wang, Jinfang Zhang, Linli Zhang, Min Yuan et al. · 2016 · Science
77. A PGC1α-mediated transcriptional axis suppresses melanoma metastasis
    Chi Luo, Ji-Hong Lim, Yoonjin Lee, Scott R. Granter, Ajith Thomas, Francisca Vázquez, Hans R. Widlund, Pere Puigserver · 2016 · Nature
78. HPV Integration in HNSCC Correlates with Survival Outcomes, Immune Response Signatures, and Candidate Drivers
    Lada A. Koneva, Yanxiao Zhang, Shama Virani, Pelle B. Hall, Jonathan Brad McHugh, Douglas Brian Chepeha, Gregory T. Wolf, Thomas E. Carey, Laura S. Rozek, Maureen A. Sartor · 2017 · Molecular Cancer Research
79. Chromatin regulatory mechanisms and therapeutic opportunities in cancer
    Alfredo M. Valencia, Cigall Kadoch · 2018 · Nature Cell Biology
80. Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes
    Sally M. Hunter, Georgia Chenevix‐Trench, Michael S. Anglesio, Georgina L. Ryland, Raghwa N. Sharma, Yoke-Eng Chiew, Simone M. Rowley, Maria Doyle, Jason Li, C. Blake Gilks et al. · 2015 · Oncotarget
81. Screening and identification of key biomarkers in hepatocellular carcinoma: Evidence from bioinformatic analysis
    Lin Li, Qingsong Lei, Shujun Zhang, Lingna Kong, Bo Qin · 2017 · Oncology Reports
82. Unifying cancer and normal RNA sequencing data from different sources
    Qingguo Wang, Joshua Armenia, Chao Zhang, Alexander V. Penson, Ed Reznik, Liguo Zhang, Thais Minet, Angelica Ochoa, Benjamin E Gross, Christine A. Iacobuzio–Donahue et al. · 2018 · Scientific Data
83. Genetic landscape of metastatic and recurrent head and neck squamous cell carcinoma
    Matthew Louis Hedberg, Gerald Goh, Simion I. Chiosea, Julie E. Bauman, Maria L. Freilino, Yan Zeng, Lin Wang, Brenda B. Diergaarde, William E. Gooding, Vivian Wai Yan Lui et al. · 2015 · Journal of Clinical Investigation
84. MCL-1 is a prognostic indicator and drug target in breast cancer
    Kirsteen J. Campbell, Sandeep Dhayade, Nicola Ferrari, Andrew H. Sims, Emma R. Johnson, Susan M. Mason, Ashley Dickson, Kevin M. Ryan, Gabriela Kalna, Joanne Edwards et al. · 2018 · Cell Death and Disease
85. Unique Genetic and Survival Characteristics of Invasive Mucinous Adenocarcinoma of the Lung
    Hyo Sup Shim, Mari Mino Kenudson, Zongli Zheng, Matthew R. Liebers, Yoon Jin Cha, Quan Van Ho, Maristela Lika Onozato, Long P. Le, Rebecca Suk Heist, Anthony John Iafrate · 2015 · Journal of Thoracic Oncology
86. OncomiR: an online resource for exploring pan-cancer microRNA dysregulation
    Nathan W. Wong, Yuhao Chen, Shuai Chen, Xiaowei Wang · 2017 · Bioinformatics
87. Mutation patterns in a population-based non-small cell lung cancer cohort and prognostic impact of concomitant mutations in KRAS and TP53 or STK11
    Linnéa La Fleur, Elin Falk-Sörqvist, Patrik Smeds, Anders Berglund, Magnus Sundström, Johanna SM Mattsson, Eva Brandén, Hirsh Koyi, Johan Isaksson, Hans Brunnström et al. · 2019 · Lung Cancer
88. Homologous recombination deficiency status-based classification of high-grade serous ovarian carcinoma
    Hisamitsu Takaya, Hidekatsu Nakai, Shiro Takamatsu, Masaki Mandai, Noriomi Matsumura · 2020 · Scientific Reports
89. Selenium detoxification is required for cancer-cell survival
    Anne E. Carlisle, Namgyu Lee, Asia N. Matthew-Onabanjo, Meghan E. Spears, Sung Jin Park, Daniel Youkana, Mihir B. Doshi, Austin Peppers, Rui Li, Alexander B. Joseph et al. · 2020 · Nature Metabolism
90. Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
    Ringel, Till, Frey, Nina, Ringnalda, Femke, Janjuha, Sharan, Cherkaoui, Sarah, Butz, Stefan, Srivatsa, Sumana, Pirkl, Martin, Russo, Giancarlo, Villiger, Lukas et al. · 2020 · Cell Stem Cell
91. Therapeutic targeting of tumor suppressor genes
    Luc G.T. Morris, Timothy An-thy Chan · 2014 · Cancer
92. Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers
    Leonard D. Goldstein, James Lee, Florian Gnad, Christiaan N. Klijn, Annalisa Schaub, Jens Reeder, Anneleen Daemen, Corey E. Bakalarski, Thomas Holcomb, David S. Shames et al. · 2016 · Cell Reports
93. Three molecular pathways model colorectal carcinogenesis in L ynch syndrome
    Aysel Ahadova, Richard Gallon, Johannes F. Gebert, Alexej Ballhausen, Volker Endris, Martina Kirchner, Albrecht Stenzinger, John Burn, Magnus von Knebel Doeberitz, Hendrik Bläker et al. · 2018 · International Journal of Cancer
94. Mutant p53: it’s not all one and the same
    Margaret C. Kennedy, Scott W. Lowe · 2022 · Cell Death and Differentiation
95. Predicting responses to platin chemotherapy agents with biochemically-inspired machine learning
    Mucaki, Eliseos J., Zhao, Jonathan Z. L., Lizotte, Daniel J., Rogan, Peter K. · 2019 · Signal Transduction and Targeted Therapy
96. A TCF4-dependent gene regulatory network confers resistance to immunotherapy in melanoma
    Pozniak, Joanna, Pedri, Dennis, Landeloos, Ewout, Van Herck, Yannick, Antoranz, Asier, Vanwynsberghe, Lukas, Nowosad, Ada, Roda, Niccolò, Makhzami, Samira, Bervoets, Greet et al. · 2024 · Cell
97. Deubiquitylase OTUD3 regulates PTEN stability and suppresses tumorigenesis
    Lin Yuan, Yanrong Lv, Hongchang Li, Haidong Gao, Shanshan Song, Yuan Zhang, Guichun Xing, Xiangzhen Kong, Lijing Wang, Yang Li et al. · 2015 · Nature Cell Biology
98. Precision Lasso: accounting for correlations and linear dependencies in high-dimensional genomic data
    Haohan Wang, Benjamin J. Lengerich, Bryon Aragam, Eric P. Xing · 2018 · Bioinformatics
99. Identification of a six-gene signature predicting overall survival for hepatocellular carcinoma
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