The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

Cited by (1,114)

Items 801–900 of 1,114

1. Nuclear mTOR acts as a transcriptional integrator of the androgen signaling pathway in prostate cancer
   Étienne Audet‐Walsh, Catherine R. Dufour, Tracey Yee, Fatima Z. Zouanat, Ming Yan, Georges Kalloghlian, Mathieu Vernier, Maxime Caron, Guillaume Bourque, Eleonora Scarlata et al. · 2017 · Genes & Development
2. The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells
   Kurimchak, Alison M., Herrera-Montávez, Carlos, Montserrat-Sangrà, Sara, Araiza-Olivera, Daniela, Hu, Jianping, Neumann-Domer, Ryan, Kuruvilla, Mathew, Bellacosa, Alfonso, Testa, Joseph R., Jin, Jian et al. · 2022 · Science Signaling
3. EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes
   Yinhua Jin, Nati Ha, Marta Forés, Jinyi Xiang, Christine Gläßer, Julieta A. Maldera, Gerardo Jiménez, Bruce A. Edgar · 2015 · PLoS Genetics
4. The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours
   Rokaya El Ansari, Madeleine L. Craze, Islam M. Miligy, Maria Diez, Christopher C. Nolan, Ian Ogilvie Ellis, Emad A. Rakha, Andrew R. Green · 2018 · Breast Cancer Research
5. Cyclin E1 and Rb modulation as common events at time of resistance to palbociclib in hormone receptor-positive breast cancer
   Cristina Guarducci, Martina Bonechi, Matteo Benelli, Chiara Biagioni, Giulia Boccalini, Dario Romagnoli, Roberto Verardo, Rachel Schiff, Charles Kent Osborne, Carmine De Angelis et al. · 2018 · npj Breast Cancer
6. Oncofetal HLF transactivates c-Jun to promote hepatocellular carcinoma development and sorafenib resistance
   Daimin Xiang, Wen Ce Sun, Tengfei Zhou, Cheng Zhang, Zhuo Cheng, Shichao Li, Weiqi Jiang, Ruoyu Wang, Gongbo Fu, Xiuliang Cui et al. · 2019 · Gut
7. The strange case of AMPK and cancer: Dr Jekyll or Mr Hyde?
   Diana Vara‐Ciruelos, Fiona M. Russell, David Grahame Hardie · 2019 · Open Biology
8. ANLN-induced EZH2 upregulation promotes pancreatic cancer progression by mediating miR-218-5p/LASP1 signaling axis
   Anbin Wang, Haisu Dai, Yi Gong, Chengcheng Zhang, Junjie Shu, Yuandeng Luo, Yan Jiang, Wei Liu, Ping Bie · 2019 · Journal of Experimental & Clinical Cancer Research
9. Nongenetic Evolution Drives Lung Adenocarcinoma Spatial Heterogeneity and Progression
   Daniele Tavernari, Elena Battistello, Elie Dheilly, Aaron S. Petruzzella, Marco Mina, Jessica Sordet‐Dessimoz, Solange Peters, Thorsten Krueger, David Gfeller, Nicolò Riggi et al. · 2021 · Cancer Discovery
10. Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer
    Feigin, Michael E., Akshinthala, S. Dipikaa, Araki, Kiyomi, Rosenberg, Avi Z., Muthuswamy, Lakshmi B., Martin, Bernard, Lehmann, Brian D., Berman, Hal K., Pietenpol, Jennifer A., Cardiff, Robert D. et al. · 2014 · Cancer Research
11. Clinical Genomic Sequencing of Pediatric and Adult Osteosarcoma Reveals Distinct Molecular Subsets with Potentially Targetable Alterations
    Suehara, Yoshiyuki, Alex, Deepu, Bowman, Anita, Middha, Sumit, Zehir, Ahmet, Chakravarty, Debyani, Wang, Lu, Jour, George, Nafa, Khedoudja, Hayashi, Takuo et al. · 2019 · Clinical Cancer Research
12. canSAR: an updated cancer research and drug discovery knowledgebase
    Joseph E Tym, Costas Mitsopoulos, Elizabeth A. Coker, Parisa Razaz, Amanda C. Schierz, Albert A. Antolín, Bissan Al‐Lazikani · 2015 · Nucleic Acids Research
13. BRG1/SMARCA4 Inactivation Promotes Non–Small Cell Lung Cancer Aggressiveness by Altering Chromatin Organization
    Tess Orvis, Austin J. Hepperla, Vonn Walter, Shujie Song, Jeremy M. Simon, Joel S. Parker, Matthew D. Wilkerson, Nisarg R. Desai, Michael B. Major, David Neil Hayes et al. · 2014 · Cancer Research
14. AKT1 and AKT2 isoforms play distinct roles during breast cancer progression through the regulation of specific downstream proteins
    Marina Riggio, María Cecilia Perrone, María L. Polo, María Jimena Rodriguez, María May, Martı́n C. Abba, Claudia Lanari, Virginia Novaro · 2017 · Scientific Reports
15. Membrane-type matrix metalloproteases as diverse effectors of cancer progression
    S. Pauliina Turunen, Olga Tatti-Bugaeva, Kaisa Lehti · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
16. Small-Cell Carcinomas of the Bladder and Lung Are Characterized by a Convergent but Distinct Pathogenesis
    Matthew T. Chang, Alexander V. Penson, Neil Bipinchandra Desai, Nicholas D. Socci, Ronglai Shen, Venkatraman Seshan, Ritika Kundra, Adam A. Abeshouse, Agnes J. Viale, Eugene K. Cha et al. · 2017 · Clinical Cancer Research
17. Oral inflammation promotes oral squamous cell carcinoma invasion
    Cameron Glenn-Franklin Goertzen, Hayder Mahdi, Catherine Laliberté, Tomer Meirson, Denise Eymael, Hava Gil-Henn, Marco A. O. Magalhães · 2018 · Oncotarget
18. Autophagy inhibition specifically promotes epithelial-mesenchymal transition and invasion in RAS-mutated cancer cells
    Yihua Wang, Hua Xiong, Dian Liu, Charlotte Nicole Hill, Ayse Ertay, Juanjuan Li, Yanmei Zou, Paul Miller, Eileen White, Julian Downward et al. · 2019 · Autophagy
19. DNAJB1-PRKACA fusions occur in oncocytic pancreatic and biliary neoplasms and are not specific for fibrolamellar hepatocellular carcinoma
    Monika Vyas, Jaclyn Frances Hechtman, Yanming Zhang, Ryma Benayed, Aslihan Yavas, Gökçe Aşkan, Jinru Shia, David S. Klimstra, Olca Baştürk · 2019 · Modern Pathology
20. Mutation Hotspots in the β-Catenin Gene: Lessons from the Human Cancer Genome Databases.
    Sewoon Kim, Sunjoo Jeong-Yu · 2019 · Europe PMC (PubMed Central)
21. Pan-cancer proteogenomics expands the landscape of therapeutic targets
    Sara R. Savage, Xinpei Yi, Jonathan Thomas Lei, Bo Wen, Hongwei Zhao, Yuxing Liao, Eric J. Jaehnig, Lauren K. Somes, Paul W. Shafer, Tobie D. Lee et al. · 2024 · Cell
22. Maftools: Efficient analysis, visualization and summarization of MAF files from large-scale cohort based cancer studies
    Anand Mayakonda, Harold Phillip Koeffler · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
23. MAP3K1: Genomic Alterations in Cancer and Function in Promoting Cell Survival or Apoptosis
    T. T. Pham, Steven P. Angus, Gary L. Johnson · 2013 · Genes & Cancer
24. Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma
    Bixiao Zhao, Siming Zhao, JONATHAN W. SAID, Maria J. Merino, Adebowale Adeniran, Zuoquan Xie, Cayce Nawaf, Jaehyuk Choi, Arie S. Belldegrun, Allan J. Pantuck et al. · 2016 · Proceedings of the National Academy of Sciences
25. Association of FGFR1 with ERα Maintains Ligand-Independent ER Transcription and Mediates Resistance to Estrogen Deprivation in ER+ Breast Cancer
    Luigi Formisano, Kimberly M. Stauffer, Christian D. Young, Neil E. Bhola, Ángel Guerrero Zotano, Valerie Malyvanh Jansen, Mónica M. Estrada, Katherine E. Hutchinson, Jennifer Margaret Giltnane, Luis Jesus Schwarz et al. · 2017 · Clinical Cancer Research
26. CD117/c-kit in Cancer Stem Cell-Mediated Progression and Therapeutic Resistance
    Brittni M. Foster, Danish Zaidi, Tyler R. Young, Mary E. Mobley, Bethany A. Kerr · 2018 · Biomedicines
27. Analysis of N6-Methyladenosine Methyltransferase Reveals METTL14 and ZC3H13 as Tumor Suppressor Genes in Breast Cancer
    Pengju Gong, You-Cheng Shao, Yan T. Yang, Wenjing Song, Xin He, Yifan Zeng, Sirui Huang, Lei Wei, Jingwei Zhang · 2020 · Frontiers in Oncology
28. Collateral lethality: a new therapeutic strategy in oncology
    Muller, Florian L., Aquilanti, Elisa A., DePinho, Ronald A. · 2015 · Trends in Cancer
29. Validation of <i>HER2</i> Amplification as a Predictive Biomarker for Anti–Epidermal Growth Factor Receptor Antibody Therapy in Metastatic Colorectal Cancer
    Raghav, Kanwal, Loree, Jonathan M., Morris, Jeffrey S., Overman, Michael J., Yu, Ruoxi, Meric-Bernstam, Funda, Menter, David, Korphaisarn, Krittiya, Kee, Brian, Muranyi, Andrea et al. · 2019 · JCO Precision Oncology
30. LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2
    Hannah Nguyen, Abdellah Allali‐Hassani, Stephen Antonysamy, Shawn S. Chang, Lisa Hong Chen, Carmen Curtis, Spencer Emtage, Fan Li, T. Gheyi, Fengling Li et al. · 2015 · Journal of Biological Chemistry
31. RNA-guided isomerization of uridine to pseudouridine—pseudouridylation
    Yi‐Tao Yu, U. Thomas Meier · 2014 · RNA Biology
32. A Unique Subset of Epithelial Ovarian Cancers with Platinum Sensitivity and PARP Inhibitor Resistance
    Raphaël Ceccaldi, Kevin W. O’Connor, Kent William Mouw, Adam Y. Li, Ursula A. Matulonis, Alan D. D’Andrea, Panagiotis A. Konstantinopoulos · 2015 · Cancer Research
33. Targeted massively parallel sequencing of angiosarcomas reveals frequent activation of the mitogen activated protein kinase pathway
    Rajmohan Murali, Raghu Chandramohan, Inga Möller, Simone L. Scholz, Michael F. Berger, Kety H. Huberman, Agnes J. Viale, Mono Pirun, Nicholas D. Socci, Nancy Bouvier et al. · 2015 · Oncotarget
34. Systematic Functional Characterization of Resistance to PI3K Inhibition in Breast Cancer
    Xiuning Le, Rajee Antony, Pedram Razavi, Daniel J. Treacy, Flora Luo, Mahmoud Ghandi, Pau Castel, Maurizio Scaltriti, Jose M Baselga, Levi A. Garraway · 2016 · Cancer Discovery
35. Pro-necrotic molecules impact local immunosurveillance in human breast cancer
    Gautier Stoll, Yuting Ma, Heng Yang, Oliver Kepp, Laurence Zitvogel, Guido Kroemer · 2017 · OncoImmunology
36. An NRG Oncology/GOG study of molecular classification for risk prediction in endometrioid endometrial cancer
    Casey M. Cosgrove, David Tritchler, David E. Cohn, David Gardner Mutch, Craig M. Rush, Heather A. Lankes, William Thomas Creasman, David Scott Miller, Nilsa C. Ramirez, Melissa Ann Geller et al. · 2017 · Gynecologic Oncology
37. CCNE1 Amplification as a Predictive Biomarker of Chemotherapy Resistance in Epithelial Ovarian Cancer
    J Górski, Frederick R. Ueland, Jill Kolesar · 2020 · Diagnostics
38. A modular master regulator landscape controls cancer transcriptional identity
    Evan Paull, Àlvaro Aytés, Sunny J. Jones, Prem S. Subramaniam, Federico Manuel Giorgi, Eugene F. Douglass, Somnath Tagore, Brennan Chu, Alessandro Vasciaveo, Siyuan Zheng et al. · 2021 · Cell
39. HER2/PI3K/AKT pathway in HER2-positive breast cancer: A review
    Linghui Pan, Jinling Li, Qi Xu, Zili Gao, Mao Yang, Xiaoping Wu, Xuesen Li · 2024 · Medicine
40. IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo
    Avinashnarayan Venkatanarayan, Payal Raulji, William Norton, Deepavali Chakravarti, Cristian Coarfa, Xiaohua Su, Santosh K. Sandur, Marc S. Ramirez, Jaehuk Lee, Charles V. Kingsley et al. · 2014 · Nature
41. Metabolic Vulnerabilities in Endometrial Cancer
    Frances L. Byrne, Ivan K. H. Poon, Susan C. Modesitt, Jose Luis Tomsig, Jenny D.Y. Chow, Marin E. Healy, William de C. Baker, Kristen A. Atkins, Johnathan M. Lancaster, Douglas C. Marchion et al. · 2014 · Cancer Research
42. A role for PVRL4-driven cell–cell interactions in tumorigenesis
    Natalya N. Pavlova, Christian Philipp Pallasch, Andrew E. H. Elia, Christian Joerg Braun, Thomas F. Westbrook, Michael T. Hemann, Stephen Joseph Elledge · 2013 · eLife
43. Nucleotide Biosynthetic Enzyme GMP Synthase Is a TRIM21-Controlled Relay of p53 Stabilization
    B. Ashok Reddy, Jan A. van der Knaap, Alice G.M. Bot, Adone Mohd-Sarip, Dick H. W. Dekkers, Mieke A. M. Timmermans, John W.M. Martens, Jeroen Demmers, C. Peter Verrijzer · 2014 · Molecular Cell
44. TCGA2STAT: simple TCGA data access for integrated statistical analysis in R
    Ying‐Wooi Wan, Genevera I. Allen, Zhandong Liu · 2015 · Bioinformatics
45. TWIST1-WDR5- Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis
    Reem A. Malek, Rajendra P. Gajula, Russell D. Williams, Belinda Nghiem, Brian Wesley Simons, Katriana M. Nugent, Hailun Wang, Kekoa Taparra, Ghali Lemtiri-Chlieh, Arum R. Yoon et al. · 2017 · Cancer Research
46. Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations
    Franklin W. Huang, Juan Miguel Mosquera, Andrea Garofalo, Coyin Oh, Maria B. Baco, Ali Amin‐Mansour, Bokang Rabasha, Samira Bahl, Stephanie Anne Mullane, Brian D. Robinson et al. · 2017 · Cancer Discovery
47. Genetic regulation of the RUNX transcription factor family has antitumor effects
    Ken Morita, Kensho Suzuki, Shintaro Maeda, Akihiko Matsuo, Yoshihide Mitsuda, Chieko Tokushige, Gengo Kashiwazaki, Junichi Taniguchi, Rina Maeda, Mina Noura et al. · 2017 · Journal of Clinical Investigation
48. Bronchiolar Adenoma
    Jason C. Chang, Joseph Montecalvo, Laetitia A Borsu, Shaohua Lu, Brandon T. Larsen, William D. Wallace, Wichit Sae‐Ow, Alexander Craig Mackinnon, Hyunjae Ryan Kim, Anita S. Bowman et al. · 2018 · The American Journal of Surgical Pathology
49. ELF3, ELF5, EHF and SPDEF Transcription Factors in Tissue Homeostasis and Cancer
    Ian Y. Luk, Camilla M. Reehorst, John Martin Mariadason · 2018 · Molecules
50. DNA methylation in thyroid cancer
    Carles Zafón, Joan Gil, Beatriz Pérez-González, Mireia Jordà · 2019 · Endocrine Related Cancer
51. Elevated MMP9 expression in breast cancer is a predictor of shorter patient survival
    Chitra Joseph, Mansour Abdulaziz Alsaleem, Nnamdi Orah, Pavan L. Narasimha, Islam M. Miligy, Sasagu Kurozumi, Ian Ogilvie Ellis, Nigel Patrick Mongan, Andrew R. Green, Emad A. Rakha · 2020 · Breast Cancer Research and Treatment
52. TCGAplot: an R package for integrative pan-cancer analysis and visualization of TCGA multi-omics data
    Chenqi Liao, Xiong Wang · 2023 · BMC Bioinformatics
53. The NSD Family of Protein Methyltransferases in Human Cancer
    Theodore Vougiouklakis, Ryuji Hamamoto, Yusuke Nakamura, Vassiliki Saloura · 2015 · Epigenomics
54. The role of wild type RAS isoforms in cancer
    Zhou, Bingying, Der, Channing J., Cox, Adrienne D. · 2016 · Seminars in Cell &amp; Developmental Biology
55. Regulation of antitumor miR‐144‐5p targets oncogenes: Direct regulation of syndecan‐3 and its clinical significance
    Yasutaka Yamada, Takayuki Arai, Satoko Kojima, Sho Sugawara, Mayuko Kato, Atsushi Okato, Kazuto Yamazaki, Yukio Naya, Tomohiko Ichikawa, Naohiko Seki · 2018 · Cancer Science
56. Does functional specialization of ribosomes really exist?
    Max Ferretti, Katrin Karbstein · 2019 · RNA
57. SKP2 promotes breast cancer tumorigenesis and radiation tolerance through PDCD4 ubiquitination
    Ce Li, Lutao Du, Yidan Ren, Xiaoyan Liu, Qinlian Jiao, Donghai Cui, Mingxin Wen, Chuanxin Wang, Guangwei Wei, Yunshan Wang et al. · 2019 · Journal of Experimental & Clinical Cancer Research
58. Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer
    William S. Chen, Rahul Raj Aggarwal, Li Zhang, Shuang George Zhao, GEORGE V. THOMAS, Tomasz M. Beer, David Alan Quigley, Adam Foye, Denise Playdle, Jiaoti Huang et al. · 2019 · European Urology
59. The ABC subfamily A transporters: Multifaceted players with incipient potentialities in cancer
    Michela Pasello, Anna Maria Giudice, Katia Scotlandi · 2019 · Seminars in Cancer Biology
60. The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair
    Ayesha A. Shafi, Christopher M. McNair, Jennifer J. McCann, Mohammed Alshalalfa, Anton Shostak, Tesa Severson, Yanyun Zhu, Andries Marinus Bergman, Nicolas Gordon, Amy C. Mandigo et al. · 2021 · Nature Communications
61. PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports
    Maike J.M. Uijen, Yvonne H. W. Derks, Robin I. J. Merkx, Melline G.M. Schilham, Jens Ulrik Roosen, Bastiaan M. Privé, Sanne A. M. van Lith, Carla M.L. van Herpen, Martin Gotthardt, Sandra Heskamp et al. · 2021 · European Journal of Nuclear Medicine and Molecular Imaging
62. Classification of KRAS -Activating Mutations and the Implications for Therapeutic Intervention
    Christian William Johnson, Deborah L. Burkhart, Kevin M. Haigis · 2022 · Cancer Discovery
63. Structure of the human DICER–pre-miRNA complex in a dicing state
    Young-Yoon Lee, Hansol Lee, Haedong Kim, V. Narry Kim, Soung‐Hun Roh · 2023 · Nature
64. Mutational landscape of cancer-driver genes across human cancers
    Musalula Sinkala · 2023 · Scientific Reports
65. Conditional Selection of Genomic Alterations Dictates Cancer Evolution and Oncogenic Dependencies
    Mina, Marco, Raynaud, Franck, Tavernari, Daniele, Battistello, Elena, Sungalee, Stephanie, Saghafinia, Sadegh, Laessle, Titouan, Sanchez-Vega, Francisco, Schultz, Nikolaus, Oricchio, Elisa et al. · 2017 · Cancer Cell
66. MetAmyl: A METa-Predictor for AMYLoid Proteins
    Mathieu Emily, Anthony Talvas, Christian Delamarche · 2013 · PLoS ONE
67. Stromal Hedgehog signalling is downregulated in colon cancer and its restoration restrains tumour growth
    Marco Gerling, Nikè V.J.A. Büller, Leonard M. Kirn, Simon Joost, Oliver Frings, Benjamin Englert, Åsa Bergström, Raoul Kuiper, Leander Blaas, Mattheus C.B. Wielenga et al. · 2016 · Nature Communications
68. ZEB1‐mediated melanoma cell plasticity enhances resistance to MAPK inhibitors
    Geoffrey Richard, Stéphane Dalle, Marie‐Ambre Monet, Maud Plaschka, Amelie M. Boespflug, Roxane M. Pommier, Arnaud de la Fouchardière, Marie Perier‐Muzet, Lauriane Depaepe, Romain Barnault et al. · 2016 · EMBO Molecular Medicine
69. Epigenetics of malignant melanoma
    Bruce Moran, Romina Silva, Antoinette Sabrina Perry, William M. Gallagher · 2017 · Seminars in Cancer Biology
70. Exploiting DNA repair defects in colorectal cancer
    Nicole Megan Reilly, Luca Novara, Federica Di Nicolantonio, Alberto Bardelli · 2019 · Molecular Oncology
71. Genomic analysis of low‐grade serous ovarian carcinoma to identify key drivers and therapeutic vulnerabilities
    Dane Anthony Cheasley, Abhimanyu Nigam, Magnus Zethoven, Sally M. Hunter, Dariush Etemadmoghadam, Timothy J. Semple, Prue E. Allan, Mark Stafford Carey, Marta Llauradó Fernández, Amy Dawson et al. · 2020 · The Journal of Pathology
72. KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis
    Rabara, Dana, Tran, Timothy H., Dharmaiah, Srisathiyanarayanan, Stephens, Robert M., McCormick, Frank, Simanshu, Dhirendra K., Holderfield, Matthew · 2019 · Proceedings of the National Academy of Sciences
73. A COL11A1-correlated pan-cancer gene signature of activated fibroblasts for the prioritization of therapeutic targets
    Dongyu Jia, Zhenqiu Liu, Nan Deng, Tuan Zea Tan, Ruby Yun‐Ju Huang, Barbie Taylor‐Harding, Dong‐Joo Cheon, Kate Lawrenson, Wolf Ruprecht Wiedemeyer, Ann E. Walts et al. · 2016 · Cancer Letters
74. ROS1 Fusions Rarely Overlap with Other Oncogenic Drivers in Non–Small Cell Lung Cancer
    Jessica J. Lin, Lauren L. Ritterhouse, Siraj Mahamed Ali, Mark Bailey, Alexa Betzig Schrock, Justin F. Gainor, Lorin A. Ferris, Mari A. Mino-Kenudson, Vincent A. Miller, Anthony John Iafrate et al. · 2017 · Journal of Thoracic Oncology
75. Role of Rad51 and DNA repair in cancer: A molecular perspective
    Erik Laurini, Domenico Marson, Alice Fermeglia, Suzana Aulić, Maurizio Fermeglia, Sabrina Pricl · 2020 · Pharmacology & Therapeutics
76. The m6A readers YTHDF1 and YTHDF3 aberrations associated with metastasis and predict poor prognosis in breast cancer patients.
    Anita Ramesh, Paramasivam Arumugam, Jayaseelan Vijayashree Priyadharsini, Chitra Srinivasan · 2020 · PubMed Central
77. FAPI PET/CT: Will It End the Hegemony of 18F-FDG in Oncology?
    Rodney J. Hicks, Peter D. Roselt, Kumarswamy G. Kallur, Richard W. Tothill, Linda Mileshkin · 2020 · Journal of Nuclear Medicine
78. In vivo genome-wide CRISPR screen reveals breast cancer vulnerabilities and synergistic mTOR/Hippo targeted combination therapy
    Meiou Dai, Gang Yan, Ni Wang, Girija Daliah, Ashlin M. Edick, Sophie Poulet, Julien Boudreault, Suhad Ali, Sergio A. Burgos, J J Lebrun · 2021 · Nature Communications
79. The HIF target MAFF promotes tumor invasion and metastasis through IL11 and STAT3 signaling
    Eui Jung Moon, Stephano S. Mello, Caiyun Grace Li, Jen‐Tsan Chi, Kaushik N. Thakkar, Jacob G. Kirkland, Edward L. LaGory, Ik Jae Lee, Anh N. Diep, Yu Rebecca Miao et al. · 2021 · Nature Communications
80. Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer
    Christopher Jon Hanley, Sara Waise, Matthew J. Ellis, Maria Antonette Lopez, Wai Y. Pun, Julian Taylor, Rachel Parker, Lucy Kimbley, Serena Chee, Emily Clare Shaw et al. · 2023 · Nature Communications
81. PI3Kβ controls immune evasion in PTEN-deficient breast tumours
    Johann S. Bergholz, Qiwei Wang, Qi Wang, Michelle L. Ramseier, Sanjay M. Prakadan, Weihua Wang, Rong Fang, Sheheryar Kairas Kabraji, Qian Zhou, G. Kenneth Gray et al. · 2023 · Nature
82. Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End
    Amanda R. Wasylishen, Guillermina Lozano · 2016 · Cold Spring Harbor Perspectives in Medicine
83. Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential.
    Roselyne M. Labbe, Andreana Holowatyj, Zeng-Quan Yang · 2013 · Europe PMC (PubMed Central)
84. Next generation sequencing in cancer research and clinical application
    Derek Shyr, Qi Liu · 2013 · Biological Procedures Online
85. Exome Sequencing Landscape Analysis in Ovarian Clear Cell Carcinoma Shed Light on Key Chromosomal Regions and Mutation Gene Networks
    Ryusuke Murakami, Noriomi Matsumura, J.B. Brown, Koichiro Higasa, Takanobu Tsutsumi, Mayumi Kamada, Hisham Abou-Taleb, Yuko Hosoe, Sachiko Kitamura, Ken D Yamaguchi et al. · 2017 · American Journal Of Pathology
86. Role of Dopamine Receptors in the Anticancer Activity of ONC201
    Christina Leah B. Kline, Marie D. Ralff, Amriti R. Lulla, Jessica Wagner, Philip H. Abbosh, David T. Dicker, Joshua E. Allen, Wafik S. El‐Deiry · 2017 · Neoplasia
87. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer
    Yun Pyo Kang, Laura Torrente, Aimee Falzone, Cody M. Elkins, Min Liu, John M. Asara, Christian C. Dibble, Gina M. DeNicola · 2019 · eLife
88. Isomerization of BRCA1–BARD1 promotes replication fork protection
    Manuel Daza-Martín, Katarzyna Starowicz, Mohammed Jamshad, Stephanie Tye, George E. Ronson, Hannah L. Mackay, Anoop Singh Chauhan, Alexandra K. Walker, Helen R Stone, James F. J. Beesley et al. · 2019 · Nature
89. Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma
    Gabriel J. Starrett, Manisha Thakuria, Tianqi Chen, Christina Marcelus, Jingwei Cheng, Jason Nomburg, Aaron R. Thorner, Michael K. Slevin, Winslow Powers, Robert Burns et al. · 2020 · Genome Medicine
90. Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy
    Matthias Gromeier, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike T. Beaubier, Hai Yan, Yiping He, Annick Desjardins et al. · 2021 · Nature Communications
91. Loss of PPP2R2A Inhibits Homologous Recombination DNA Repair and Predicts Tumor Sensitivity to PARP Inhibition
    Peter Kalev, Michal Šimíček, Iria Vázquez, Sebastian Munck, Liping Chen, Thomas Soin, Natasha Danda, Wen Ling Chen, Anna A. Sablina · 2012 · Cancer Research
92. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression
    Schrecengost, Randy S., Dean, Jeffry L., Goodwin, Jonathan F., Schiewer, Matthew J., Urban, Mark W., Stanek, Timothy J., Sussman, Robyn T., Hicks, Jessica L., Birbe, Ruth C., Draganova-Tacheva, Rossitza A. et al. · 2014 · Cancer Research
93. A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer
    Nada A Al Tassan, Nicola Whiffin, Fay J. Hosking, Claire Palles, Susan Mary Farrington, Sara E. Dobbins, Rebecca Harris, Maggie Gorman, Albert Tenesa, Brian F. Meyer et al. · 2015 · Scientific Reports
94. Metastatic tumor evolution and organoid modeling implicate TGFBR2as a cancer driver in diffuse gastric cancer
    Lincoln D. Nadauld, Sarah Garcia, Georges Natsoulis, John Bell, Laura K. Miotke, Erik S. Hopmans, Hua Xu, Reetesh K. Pai, Curt Palm, John F. Regan et al. · 2014 · Genome biology
95. Clinical Analysis and Interpretation of Cancer Genome Data
    Eliezer M. Van Allen, Nikhil Wagle, Mia Alyce Levy · 2013 · Journal of Clinical Oncology
96. Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition
    Hongyuan Chang, Yuwei Liu, Mengzhu Xue, Haiyue Liu, Shaowei Du, Liwen Zhang, Peng Wang · 2016 · Nucleic Acids Research
97. Lollipops in the Clinic: Information Dense Mutation Plots for Precision Medicine
    Jeremy J. Jay, Cory Brouwer · 2016 · PLoS ONE
98. Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development
    Krinio Giannikou, Izabela A. Malinowska, Trevor J. Pugh, Rachel Yan, Yuen‐Yi Tseng, Coyin Oh, Jaegil Kim, Magdalena Ewa Tyburczy, Yvonne I. Chekaluk, Yang Liu et al. · 2016 · PLoS Genetics
99. HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer
    Xiaowei Xu, Carmine De Angelis, Kathleen A. Burke, Agostina Nardone, Huizhong Hu, Lanfang Qin, Jamunarani Veeraraghavan, Vidyalakshmi Sethunath, Laura M. Heiser, Nicholas Wang et al. · 2017 · Clinical Cancer Research
100. Genomic profiling of ER + breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance
     Jennifer Margaret Giltnane, Katherine E. Hutchinson, Thomas P. Stricker, Luigi Formisano, Christian D. Young, Monica Valeria Estrada, Mellissa J. Nixon, Liping Du, Violeta M. Sanchez, Paula I. González Ericsson et al. · 2017 · Science Translational Medicine