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Combined (Thalamotomy and Stimulation) Stereotactic Surgery of the VIM Thalamic Nucleus for Bilateral Parkinson Disease

Benabid, A.L., Pollak, P., Louveau, A., Henry, S., de Rougemont, J.·1987·Stereotactic and Functional Neurosurgery

Abstract

Stereotactic thalamotomy of the thalamic nucleus ventralis intermedius (VIM) is routinely used for movement disorders. During this procedure, it has been observed that high-frequency (100 Hz) stimulation of VIM was able to stop the extrapyramidal tremor. In patients with bilateral tremor of extrapyramidal origin, who were resistant to drug therapy, the therapeutic protocol associated (1) a radiofrequency VIM thalamotomy for the most disabled side, and (2) a continuous VIM stimulation for the other side using stereotactically implanted electrodes, connected to subcutaneous stimulators. VIM thalamotomy relieved the tremor in all operated cases. Side effects were mild and regressive, VIM stimulation strongly decreasedthe tremor but failed to suppress it as completely as thalamotomy did. This was due in part to the fact that programmable stimulator frequency rate is limited to 130 Hz, while it appeared that the optimal stimulation frequency was 200 Hz. This therapeutic protocol appears to be of interest for patients with bilateralextrapyramidal movement disorders.

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Metadata

Authors
Benabid, A. L., Pollak, P., Louveau, A., Henry, S., & de Rougemont, J.
Venue
Stereotactic and Functional Neurosurgery
Publisher
S. Karger AG
Published
1987
Volume
50
Issue
1-6
Pages
344-346
ISSN
  • 1011-6125 (ISSN-L)
  • 1423-0372
OpenAlex
W2082851956
Cited by
1,378
References
0
FWCI
0.00
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Combined (Thalamotomy and Stimulation) Stereotactic Surgery of the VIM Thalamic Nucleus for Bilateral Parkinson Disease. https://app.cochat.ai/papers/10.1159/000100803
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Benabid, A. L., Pollak, P., Louveau, A., Henry, S., & de Rougemont, J. (1987). Combined (Thalamotomy and Stimulation) Stereotactic Surgery of the VIM Thalamic Nucleus for Bilateral Parkinson Disease. Stereotactic and Functional Neurosurgery. https://doi.org/10.1159/000100803

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