Cited by 39Dermatology and Skin DiseasesPain Mechanisms and TreatmentsMusculoskeletal pain and rehabilitation

Are itch and chronic pain associated in adults? Results of a large population survey in Norway

Dalgard, Florence, Dawn, Aerlyn G., Yosipovitch, Gil·2007·Dermatology

Abstract

BACKGROUND: Few large-scale epidemiological studies have been performed on the prevalence of itch. Itch and pain are common and complex symptoms which contribute to the burden of disease. Although there is antagonistic interaction between itch and pain, there are also many similarities in their pathophysiology. OBJECTIVE: To investigate possible associations between chronic itch and chronic pain in a large population. METHODS: The design was cross-sectional. 18,770 adults completed a self-administered questionnaire addressing sociodemographic factors, psychosocial factors and self-reported health including chronic itch and chronic pain. RESULTS: Individuals reporting pain and itch were more likely to be women (80 and 60%, respectively, compared to 55% in the total sample), had a lower income (49 and 37% compared to 32%), were more likely to be depressed (36 and 20% compared to 11%) and reported poorer well-being (74 and 34% compared to 25%). In an adjusted logistic regression, chronic pain was strongly associated with chronic itch (OR = 1.79, 95% CI = 1.43-2.24). CONCLUSION: This study demonstrates the association of chronic itch and chronic pain and points out the need of further studies that focus on both symptoms in dermatological diseases.

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Crossref · 10.1159/000100881

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Authors
Dalgard, F., Dawn, A. G., & Yosipovitch, G.
Affiliations
  • University of Oslo (NO)
  • Wake Forest University Health Sciences (US)
Venue
Dermatology
Publisher
S. Karger AG
Published
2007
Volume
214
Issue
4
Pages
305-309
ISSN
  • 1018-8665 (ISSN-L)
  • 1421-9832
OpenAlex
W2027590027
Cited by
39
References
22
Citations by year
2026: 1 · 2025: 2 · 2024: 5 · 2023: 4 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 4 · 2017: 2 · 2016: 2 · 2015: 3 · 2012: 2
FWCI
2.55
Type
journal article
Language
en
Open access
closed
Locations
  • Dermatology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
Keywords
chronic pruritus, chronic pain, pruritus, prevalence, sex differences, socioeconomic status, income, depression, well-being, psychosocial factors, skin diseases, symptom comorbidity
MeSH terms
Adult, Aged, Chronic Disease, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Norway, Pain, Pruritus

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