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Measurement of Optical Path Length for Cerebral Near-Infrared Spectroscopy in Newborn Infants

Wyatt, J.S., Cope, M., Delpy, D.T., van der Zee, P., Arridge, S., Edwards, A.D., Reynolds, E.O.R.·1990·Developmental Neuroscience

Abstract

The time taken for an extremely short pulse of near-infrared laser light to traverse the heads of 6 preterm infants was measured after death. The values obtained were used to calculate a differential path length factor (DPF), defined as the mean distance travelled by the photons divided by the distance between the points where light entered and left the head. The DPF was found to be 4.39 +/- 0.28. Knowledge of this factor will permit accurate quantitative measurements to be made by near-infrared spectroscopy of a range of indices of cerebral oxygenation and haemodynamics in live infants.

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Metadata

Authors
Wyatt, J. S., Cope, M., Delpy, D. T., van der Zee, P., Arridge, S., Edwards, A. D., & Reynolds, E. O. R.
Venue
Developmental Neuroscience
Publisher
S. Karger AG
Published
1990
Volume
12
Issue
2
Pages
140-144
ISSN
  • 0378-5866 (ISSN-L)
  • 1421-9859
OpenAlex
W2057377618
Cited by
182
References
0
FWCI
11.56
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Measurement of Optical Path Length for Cerebral Near-Infrared Spectroscopy in Newborn Infants. https://app.cochat.ai/papers/10.1159/000111843
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Wyatt, J. S., Cope, M., Delpy, D. T., van der Zee, P., Arridge, S., Edwards, A. D., & Reynolds, E. O. R. (1990). Measurement of Optical Path Length for Cerebral Near-Infrared Spectroscopy in Newborn Infants. Developmental Neuroscience. https://doi.org/10.1159/000111843

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