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Alternating Demineralization and Remineralization of Artificial Enamel Lesions
Abstract
Mineral loss and uptake in artificial enamel lesions was investigated by pH cycling: samples were subjected to a sequence of de- and remineralizing solutions. The ratio between de- and remineralization per day and the presence of fluoride in the remineralizing solution were varied among different experimental groups. Calcium, phosphate and fluoride uptake and loss were measured. The lesions were also studied with a hardness tester and micro radiography. The results show a difference in remineralization mechanism between continuously remineralized and pH-cycled samples (with respect to Ca/P ratios). With fluoride present, after some time, ‘arrested’ carious lesions are formed, which can hardly be further demineralized or remineralized. This is in agreement with clinical findings of remineralization in areas with fluoridation of the drinking water.
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Citations
Cited by
Dental caries: a dynamic disease process
Featherstone, J. (2008) · Australian Dental Journal · doi:10.1111/j.1834-7819.2008.00064.x · Cited by 507
Current concepts on the theories of the mechanism of action of fluoride
Cate, J. M. T. (1999) · Acta Odontologica Scandinavica · doi:10.1080/000163599428562 · Cited by 335
pH-cycling of enamel and dentin lesions in the presence of low concentrations of fluoride
ten Gate, J. M., Buijs, M. J., & Damen, J. J. M. (1995) · European Journal of Oral Sciences · doi:10.1111/j.1600-0722.1995.tb01858.x · Cited by 74
Laboratory and human studies to estimate anticaries efficacy of fluoride toothpastes
Tenuta, L. M. A., & Cury, J. A. (2013) · Monographs in Oral Science · doi:10.1159/000350479 · Cited by 58
In Vitro Models Used in Cariology Mineralisation Research—A Review of the Literature
Fu, Y., Ekambaram, M., Li, K. C., Zhang, Y., Cooper, P. R., & Mei, M. L. (2024) · Dentistry Journal · doi:10.3390/dj12100323 · Cited by 26
Metadata
- Authors
- ten Cate, J. M., & Duijsters, P. P. E.
- Venue
- Caries Research
- Publisher
- S. Karger AG
- Published
- 1982
- Volume
- 16
- Issue
- 3
- Pages
- 201-210
- ISSN
- 0008-6568 (ISSN-L)
- 1421-976X
- OpenAlex
- W2045631815
- Cited by
- 630
- References
- 0
- FWCI
- 34.12
- Type
- journal article
- Language
- en
- Open access
- closed
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- ten Cate, J. M., & Duijsters, P. P. E. (1982). Alternating Demineralization and Remineralization of Artificial Enamel Lesions. Caries Research. https://doi.org/10.1159/000260599
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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