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Effects of interventions involving the family in the treatment of adult patients with chronic physical diseases: A meta-analysis.
Abstract
BACKGROUND: Families can have considerable influence on the health of a patient with a chronic physical disease, and attempts have been made to optimise treatment by involving family members. This meta-analysis aimed to systematically assess the effects of family-oriented interventions on adults with chronic physical diseases. METHODS: A systematic literature search was conducted to identify randomised clinical trials that have evaluated the effects of family-based interventions for adult patients compared to standard treatment. Interventions were classified as psychoeducation or addressing family relationships. The outcomes studied were the patient's physical and mental health and the health of the family members. The effect sizes were calculated as Hedges' g and combined using random-effects models. RESULTS: Fifty-two relevant randomised controlled trials (including 8,896 patients) were extracted. The main disease groups were cardiovascular diseases including stroke, cancer and arthritis. Meta-analysis showed that family involvement resulted in significantly better health than standard treatment for all outcomes. The mean overall effect sizes were 0.32 for the patients' physical health, 0.28 for the patients' mental health and 0.35 for the family members' health. Overall, the effects were not large, but they were broad, significant and stable over a long period of time. There was a tendency towards higher effects in favour of relationship-focused family interventions compared to educational interventions. CONCLUSIONS: Psychosocial interventions involving family members in the treatment of chronic physical diseases have positive effects on the health outcome for both the patient and his/her family. Further high-quality research is necessary to investigate differential effects.
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“Within the broader context of chronic illness, research has shown that interventions targeting both patients and FCs together, known as dyad interventions, are more effective for both patients and their FCs, compared to interventions focused solely on patients or FCs [45, 46].”
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BackgroundTRIVEDI, R. B., Hirayama, S. K., Risbud, R. D., Suresh, M., Humber, M. B., Butler, K., Razze, A., Timko, C., Nelson, K. M., Zulman, D. M., et al. (2023) · JMIR Formative Research · doi:10.2196/43903 · Cited by 3
“Asynchronous communication [4,8,9] between program participants and facilitators is less common.”
BackgroundShah, R., Finlay, A. Y., Ali, F. M., Otwombe, K. N., Nixon, S. J., George, L., Evans, M., Ingram, J. R., & Salek, S. (2024) · Diabetes Obesity and Metabolism · doi:10.1111/dom.16058 · Cited by 3
A Qualitative Description of a Family Intervention for Breast Cancer Survivors Experiencing Fatigue
Bellin, M. H., Oktay, J. S., Scarvalone, S., Appling, S., & Helzlsouer, K. J. (2015) · Journal of Psychosocial Oncology · doi:10.1080/07347332.2015.1046010 · Cited by 3
“Studies with other chronic disease populations have similarly shown that family involvement results in significantly better health and mental health outcomes for the patient as well as enhanced health functioning among family members (Hartmann et al., 2010).”
BackgroundPsicoterapia familiar en pacientes con hipertensión no controlada. Estudio preliminar
Puga-Garfias, L. V., Mejía-Rodríguez, O., Kanán-Cedeño, E. G., Caballero-Díaz, P., Medellín-Fontes, M. M., & Rodríguez-Orozco, A. R. (2021) · Archivos de cardiología de México · doi:10.24875/acm.20000505 · Cited by 3
Foundations for clinical practice
Umphred, D. A., LAZARO, R. T., & Roller, M. L. (2013) · Elsevier eBooks · doi:10.1016/b978-0-323-07586-2.00010-8 · Cited by 3
4. Community-Based Interventions
McDermott, R. J., Bryant, C. A., Mayer, A. B., Martinasek, M. P., Baldwin, J. A., & Vamos, S. (2016) · American Public Health Association eBooks · doi:10.2105/9780875532783ch04 · Cited by 3
Sándor, Z., Látos, M., & Csabai, M. (2020) · Orvosi Hetilap · doi:10.1556/650.2020.31827 · Cited by 3
“Az intervenciós kutatások eredményei szerint ugyanis a társas támogatás fejlesztésére, javítására irányuló pszi-choszociális intervenciók potenciálisan hozzájárulhatnak a betegek pozitívabb egészségi állapotához [33, 34].”
Heyne, S., Kuzmanova, A., Esser, P., Linse, K., Günther, R., Mehnert-Theuerkauf, A., & Metelmann, M. (2025) · BMC Neurology · doi:10.1186/s12883-025-04440-w · Cited by 2
“However, couple-and family-oriented interventions may also be valuable in ALS, given their demonstrated benefits in other chronic conditions (e.g., stroke, cancer, arthritis) [61].”
Dyadic psychosocial interventions in couples facing multiple sclerosis: a systematic review
Nielsen, J., Verhülsdonk, S., Lansu, A., Monsef, I., Skoetz, N., Kalbe, E., & Folkerts, A. (2025) · Disability and Rehabilitation · doi:10.1080/09638288.2025.2569692 · Cited by 2
“This observation aligns with a review by Hartmann et al. [64], which indicated that communication-based interventions had greater effects on the physical and mental health of patients with chronic physical diseases and their families than solely education-based interventions.”
Genograma y ecomapa: herramientas de abordaje para el médico familiar
Barbosa, A. V. B., & Solano, E. L. G. (2021) · Desarrollo economía y sociedad · doi:10.38017/23228040.744 · Cited by 2
The family as a unit of analysis: a challenge for nursing
García‐Vivar, C. (2013) · Investigación y Educación en Enfermería · doi:10.17533/udea.iee.17493 · Cited by 2
“5,6 Also, it seems reductionist to maintain the traditional approach of care aimed at the patient given that the individual is a bio-psychosocial being who requires a holistic approach that contemplates al its dimensions (biological, psychological, family, social, and spiritual).”
Introduction to OA, communication, and person-centered care
Østerås, N., & Bunzli, S. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99269-5.00001-3 · Cited by 2
The Effect of Family Psychoeducation on Burden of Care in Families with Type I Diabetic Children
Farahmandnia, B., Dashtbozorgi, B., renani, H. A., Latifi, S. M., & Aminzadeh, M. (2017) · Jundishapur Journal of Chronic Disease Care · doi:10.5812/jjcdc.12874 · Cited by 2
“The result is in agreement with the findings of the current study (30).”
BackgroundResultSteigerung von Selbstfürsorge und Mitgefühl in der eigenen Beziehung: Ein Gruppentraining für Paare
Aguilar‐Raab, C. (2020) · Psychotherapie: Praxis · doi:10.1007/978-3-662-60318-5_9 · Cited by 2
Evidence for the Efficacy and Effectiveness of Systemic Family Therapy
Carr, A. (2020) · Wiley eBooks · doi:10.1002/9781119790181.ch6 · Cited by 3
Death anxiety and interment stress family interventions for Filipino older adultsPreprint
VILLAFUERTE, S. (2022) · doi:10.31124/advance.20261148 · Cited by 2
Zhang, X., Ho, G. W. K., & Mak, Y. W. (2024) · PLoS ONE · doi:10.1371/journal.pone.0298178 · Cited by 1
Principais intervenções de enfermagem no apoio a cuidadores familiares: uma revisão integrativa
Silva, A. L. B., do Nascimento, J. W. A., & Gonçalves, F. R. (2020) · Nursing Edição Brasileira · doi:10.36489/nursing.2020v23i271p4949-4960 · Cited by 1
“Estas intervenções são relatadas como benéficas para os cuidadores famíliares, de modo que alguns estudos encontraram efeitos positivos na preparação, competência, recompensas e nas necessidades dos cuidadores familiares(28, 34).”
BackgroundSystemische Familienmedizin – Grundlagen, Wirksamkeit und klinische Implementierung
Haun, M. W. (2023) · Kontext · doi:10.13109/kont.2023.54.3.215 · Cited by 1
Metadata
- Authors
- Hartmann, M., Bäzner, E., Wild, B., Eisler, I., & Herzog, W.
- Affiliations
- Heidelberg University (DE)
- King's College London (GB)
- Venue
- Psychotherapy and Psychosomatics
- Publisher
- S. Karger AG
- Published
- 2010
- Volume
- 79
- Issue
- 3
- Pages
- 136-148
- ISSN
- 0033-3190 (ISSN-L)
- 1423-0348
- OpenAlex
- W2047620292
- Cited by
- 261
- References
- 110
- Citations by year
- 2026: 11 · 2025: 12 · 2024: 10 · 2023: 11 · 2022: 20 · 2021: 18 · 2020: 23 · 2019: 21 · 2018: 15 · 2017: 24 · 2016: 22 · 2015: 20 · 2014: 25 · 2013: 14 · 2012: 7
- FWCI
- 2.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychotherapy and Psychosomatics (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- Bundesministerium für Bildung und Forschung
- Topics
- Health Sciences › Nursing › Research and Theory › Nursing care and research
- Social Sciences › Psychology › Clinical Psychology › Family Caregiving in Mental Illness
- Social Sciences › Psychology › Clinical Psychology › Family Support in Illness
- Keywords
- family involvement, family-centered intervention, chronic physical illness, psychosocial interventions, psychoeducation, family relationships, patient mental health, physical health, cardiovascular disease, stroke, cancer, arthritis
- MeSH terms
- Adaptation, Psychological, Adult, Chronic Disease, Family Relations, Family Therapy, Health Status, Humans, Randomized Controlled Trials as Topic, Treatment Outcome, Caregivers
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