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Cited by 3,539

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila

Open access
Moy, Ryan H., Cherry, Sara·2013·Journal of Innate Immunity

Abstract

Autophagy is a highly conserved degradative pathway that has rapidly emerged as a critical component of immunity and host defense. Studies have implicated autophagy genes in restricting the replication of a diverse array of pathogens, including bacteria, viruses and protozoans. However, in most cases, the in vivo role of antimicrobial autophagy against pathogens has been undefined. Drosophila provides a genetically tractable model system that can be easily adapted to study autophagy in innate immunity, and recent studies in flies have demonstrated that autophagy is an essential antimicrobial response against bacteria and viruses in vivo. These findings reveal striking conservation of antimicrobial autophagy between flies and mammals, and in particular, the role of pathogen-associated pattern recognition in triggering this response. This review discusses our current understanding of antimicrobial autophagy in Drosophila and its potential relevance to human immunity.

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Crossref · 10.1159/000350326

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Metadata

Authors
Moy, R. H., & Cherry, S.
Venue
Journal of Innate Immunity
Publisher
S. Karger AG
Published
2013
Volume
5
Issue
5
Pages
444-455
ISSN
  • 1662-811X (ISSN-L)
  • 1662-8128
OpenAlex
W2065031087
Cited by
3,539
References
48
FWCI
141.90
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila. https://app.cochat.ai/papers/10.1159/000350326
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Moy, R. H., & Cherry, S. (2013). Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila. Journal of Innate Immunity. https://doi.org/10.1159/000350326

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.