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Renal-Limited “Lupus-Like” Nephritis: How Much of a Lupus
Open accessAbstract
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by development of autoantibodies to nuclear and cytoplasmic antigens. A small subset of SLE patients who had the typical clinical features of SLE was reported to show persistently negative antinuclear antibody tests. Our report describes a 5-year-old male who presented with histopathological findings suggestive of lupus nephritis with no clinical signs or symptoms of SLE and negative autoantibodies. He was treated with corticosteroids, mycophenolate mofetil, and monthly intravenous cyclophosphamide. During the 2-year follow-up period, the proteinuria resolved and kidney function improved with continued negative autoantibody workup. This case presents a category of renal-limited “lupus-like” glomerulonephritis which can be challenging to treat and carries a poor prognosis.
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Cited by
Petri, M., Orbai, A., Alarcón, G. S., Gordon, C., Merrill, J. T., Fortin, P. R., Bruce, I. N., Isenberg, D., Wallace, D. J., Nived, O., et al. (2012) · Arthritis & Rheumatism · doi:10.1002/art.34473 · Cited by 5,322
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Furie, R. A., Aroca, G., Cascino, M. D., Garg, J. P., Rovin, B. H., Alvarez, A., Fragoso-Loyo, H., Zuta-Santillan, E., Schindler, T., Brunetta, P., et al. (2022) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2021-220920 · Cited by 459
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Metadata
- Authors
- Maziad, A. S. A., Torrealba, J., Seikaly, M. G., Hassler, J. R., & Hendricks, A. R.
- Venue
- Case Reports in Nephrology and Dialysis
- Publisher
- S. Karger AG
- Published
- 2017-05-08
- Volume
- 7
- Issue
- 2
- Pages
- 43-48
- ISSN
- 2296-9705 (ISSN-L)
- OpenAlex
- W2613529089
- Cited by
- 1,299
- References
- 0
- FWCI
- 73.12
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Renal-Limited “Lupus-Like” Nephritis: How Much of a Lupus. https://app.cochat.ai/papers/10.1159/000475493
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- Maziad, A. S. A., Torrealba, J., Seikaly, M. G., Hassler, J. R., & Hendricks, A. R. (2017). Renal-Limited “Lupus-Like” Nephritis: How Much of a Lupus. Case Reports in Nephrology and Dialysis. https://doi.org/10.1159/000475493
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
