The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Hydrogen Peroxide: A Potential Wound Therapeutic Target
Open accessAbstract
Hydrogen peroxide (H 2 O 2) is a topical antiseptic used in wound cleaning which kills pathogens through oxidation burst and local oxygen production. H 2 O 2 has been reported to be a reactive biochemical molecule synthesized by various cells that influences biological behavior through multiple mechanisms: alterations of membrane potential, generation of new molecules, and changing intracellular redox balance, which results in activation or inactivation of different signaling transduction pathways. Contrary to the traditional viewpoint that H 2 O 2 probably impairs tissue through its high oxidative property, a proper level of H 2 O 2 is considered an important requirement for normal wound healing. Although the present clinical use of H 2 O 2 is still limited to the elimination of microbial contamination and sometimes hemostasis, better understanding towards the sterilization ability and cell behavior regulatory function of H 2 O 2 within wounds will enhance the potential to exogenously augment and manipulate healing.
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Cites
Killing activity of neutrophils is mediated through activation of proteases by K+ flux
Reeves, E. P., Lu, H., Jacobs, H. L., Messina, C. G. M., Bolsover, S., Gabella, G., Potma, E. O., Warley, A., Roes, J., & Segal, A. W. (2002) · Nature · doi:10.1038/416291a · Cited by 1,153
NADPH oxidases: An overview from structure to innate immunity-associated pathologies
Panday, A., Sahoo, M. K., Osorio, D., & Batra, S. (2015) · Cellular & Molecular Immunology · doi:10.1038/cmi.2014.89 · Cited by 944
Dermal Wound Healing Is Subject to Redox Control
Roy, S., Khanna, S., Nallu, K., Hunt, T. K., & Sen, C. K. (2006) · Molecular Therapy · doi:10.1016/j.ymthe.2005.07.684 · Cited by 472
Roos, D. (2016) · British Medical Bulletin · doi:10.1093/bmb/ldw009 · Cited by 212
Ncf1 polymorphism reveals oxidative regulation of autoimmune chronic inflammation
Holmdahl, R., Sareila, O., Olsson, L. M., Bäckdahl, L., & Wing, K. (2016) · Immunological Reviews · doi:10.1111/imr.12378 · Cited by 131
Cited by
Cano Sanchez, M., Lancel, S., Boulanger, E., & Neviere, R. (2018) · Antioxidants · doi:10.3390/antiox7080098 · Cited by 574
Metadata
- Authors
- Zhu, G., Wang, Q., Lu, S., & Niu, Y.
- Venue
- Medical Principles and Practice
- Publisher
- S. Karger AG
- Published
- 2017
- Volume
- 26
- Issue
- 4
- Pages
- 301-308
- ISSN
- 1011-7571 (ISSN-L)
- 1423-0151
- OpenAlex
- W2604532556
- Cited by
- 172
- References
- 5
- FWCI
- 7.03
- Type
- journal article
- Language
- en
- Open access
- diamond
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