Cited by 20Reproductive Health and TechnologiesReproductive Biology and FertilityOvarian function and disorders

The impact of traditional medicine-based lifestyle and diet on infertility treatment in women undergoing assisted reproduction: a randomized controlled trial

Alibeigi, Zeinab, Jafari-Dehkordi, Effat, Kheiri, Soleiman, Nemati, Maryam, Mohammadi-Farsani, Gholamreza, Tansaz, Mojgan·2020·Complementary Medicine Research

Abstract

The problem of infertility is growing rapidly in the world. Traditional medicine with thousands of years of history has claimed that it can treat some kinds of infertility using nutritional and lifestyle modifications and interventions. The purpose of this study was to evaluate the effect of a traditional medicine-oriented diet and lifestyle on infertility treatment. Based on a clinical trial study, 180 infertile women who were 20–40 years old and candidates for in vitro fertilization (IVF) were randomly assigned to 2 groups: an intervention group and a control group. The intervention group used diet and lifestyle recommendations based on Iranian traditional medicine for at least 3 months. The number of ova, mature ovum number, embryo number, embryo quality, and fertilization rate were significantly higher in the intervention group than in the control group (for all items; p < 0.05). Overall pregnancy rate was significantly higher in the intervention group (35.2 vs. 12.4%; odds ratio [OR], 3.8; 95% CI, 1.8–8.3). The intervention group had a higher rate of getting spontaneous pregnancy than the control group (20.9 vs. 2.2%; OR, 11.5; 95% CI, 2.6–50.9). Chemical pregnancy was significantly higher in the intervention group (64 vs. 27.5%; OR, 4.7; 95% CI, 1.9–11.6). Diet and lifestyle modifications based on traditional medicine can contribute greatly to the infertility treatment. Thus, many infertility cases can be treated without the need to use advanced methods. In case of using assisted reproductive techniques, traditional medicine can enhance the efficiency of these methods.

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Crossref · 10.1159/000505016

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  • Alibeigi 2020 reported an RR of 2.85 (95% CI 1.53 to 5.29) for clinical pregnancy in 180 participants.

    “Alibeigi 2020 reported an RR of 2.85 (95% CI 1.53 to 5.29) in 180 participants.”

    From Preconception lifestyle advice for people with infertility (2021) · cites this paper as Alibeigi 2020

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Authors
Alibeigi, Z., Jafari-Dehkordi, E., Kheiri, S., Nemati, M., Mohammadi-Farsani, G., & Tansaz, M.
Affiliations
  • Iran University of Medical Sciences (IR)
  • Shahrekord University of Medical Sciences (IR)
  • Shahid Beheshti University (IR)
Venue
Complementary Medicine Research
Publisher
S. Karger AG
Published
2020
Volume
27
Issue
4
Pages
230-241
ISSN
  • 1424-7364 (ISSN-L)
  • 2504-2092
  • 2504-2106
OpenAlex
W3002926033
Cited by
20
References
33
Citations by year
2026: 2 · 2025: 3 · 2024: 4 · 2023: 3 · 2022: 4 · 2021: 4
FWCI
2.43
Type
journal article
Language
en
Open access
closed
Locations
  • Complementary Medicine Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Reproductive Biology and Fertility
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
Keywords
infertility, Persian medicine, lifestyle modification, in vitro fertilization, assisted reproduction, oocyte quality, embryo quality, fertilization rate, pregnancy rate, chemical pregnancy, spontaneous conception
MeSH terms
Healthy Lifestyle, Adult, Female, Fertilization in Vitro, Humans, Infertility, Female, Iran, Medicine, Traditional, Pregnancy, Pregnancy Rate, Young Adult

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