The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
DNA vaccines: roles against diseases
Open accessAbstract
Vaccination is the most successful application of immunological principles to human health. Vaccine efficacy needs to be reviewed from time to time and its safety is an overriding consideration. DNA vaccines offer simple yet effective means of inducing broad-based immunity. These vaccines work by allowing the expression of the microbial antigen inside host cells that take up the plasmid. These vaccines function by generating the desired antigen inside the cells, with the advantage that this may facilitate presentation through the major histocompatibility complex. This review article is based on a literature survey and it describes the working and designing strategies of DNA vaccines. Advantages and disadvantages for this type of vaccines have also been explained, together with applications of DNA vaccines. DNA vaccines against cancer, tuberculosis, Edwardsiella tarda, HIV, anthrax, influenza, malaria, dengue, typhoid and other diseases were explored.
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Cites
Direct Gene Transfer into Mouse Muscle in Vivo
Wolff, J. A., Malone, R. W., Williams, P., Chong, W., Acsadi, G., Jani, A., & Felgner, P. L. (1990) · Science · doi:10.1126/science.1690918 · Cited by 4,173
Contribution of CpG motifs to the immunogenicity of DNA vaccines
Klinman, D. M., Yamshchikov, G., & Ishigatsubo, Y. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.8.3635 · Cited by 507
Cited by
COVID-19 Vaccine Frontrunners and Their Nanotechnology Design
Chung, Y. H., Beiss, V., Fiering, S. N., & Steinmetz, N. F. (2020) · ACS Nano · doi:10.1021/acsnano.0c07197 · Cited by 346
Digital-to-biological converter for on-demand production of biologics.
Boles, K. S., Kannan, K., Gill, J., Felderman, M., Gouvis, H., Hubby, B., Kamrud, K. I., Venter, J. C., & Gibson, D. G. (2017) · Nature Biotechnology · doi:10.1038/nbt.3859 · Cited by 80
(2023) · doi:10.3390/vaccines11050919 · Cited by 50
Stachyra, A., Redkiewicz, P., Kosson, P., Protasiuk, A., Góra-Sochacka, A., Kudla, G., & Sirko, A. (2016) · Virology Journal · doi:10.1186/s12985-016-0599-y · Cited by 42
Illouz, T., Madar, R., Biragyn, A., & Okun, E. (2019) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2018.10.004 · Cited by 22
Metadata
- Authors
- Khan, K. H.
- Venue
- GERMS
- Publisher
- MDPI AG
- Published
- 2013-03
- Volume
- 3
- Issue
- 1
- Pages
- 26-35
- ISSN
- 2248-2997 (ISSN-L)
- OpenAlex
- W2023520005
- Cited by
- 212
- References
- 2
- FWCI
- 5.19
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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