The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
COVID-19 Vaccine Frontrunners and Their Nanotechnology Design
Open accessAbstract
Humanity is experiencing a catastrophic pandemic. SARS-CoV-2 has spread globally to cause significant morbidity and mortality, and there still remain unknowns about the biology and pathology of the virus. Even with testing, tracing, and social distancing, many countries are struggling to contain SARS-CoV-2. COVID-19 will only be suppressible when herd immunity develops, either because of an effective vaccine or if the population has been infected and is resistant to reinfection. There is virtually no chance of a return to pre-COVID-19 societal behavior until there is an effective vaccine. Concerted efforts by physicians, academic laboratories, and companies around the world have improved detection and treatment and made promising early steps, developing many vaccine candidates at a pace that has been unmatched for prior diseases. As of August 11, 2020, 28 of these companies have advanced into clinical trials with Moderna, CanSino, the University of Oxford, BioNTech, Sinovac, Sinopharm, Anhui Zhifei Longcom, Inovio, Novavax, Vaxine, Zydus Cadila, Institute of Medical Biology, and the Gamaleya Research Institute having moved beyond their initial safety and immunogenicity studies. This review analyzes these frontrunners in the vaccine development space and delves into their posted results while highlighting the role of the nanotechnologies applied by all the vaccine developers.
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Cites
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Cited by
Modifications in an Emergency: The Role of N1-Methylpseudouridine in COVID-19 Vaccines
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Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
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COVID-19 vaccines: The status and perspectives in delivery points of view
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Pokrajac, L., Abbas, A., Chrzanowski, W., Dias, G. M., Eggleton, B. J., Maguire, S., Maine, E., Malloy, T., Nathwani, J., Nazar, L., et al. (2021) · ACS Nano · doi:10.1021/acsnano.1c10919 · Cited by 365
Novel approaches for vaccine development
Gebre, M. S., Brito, L. A., Tostanoski, L. H., Edwards, D. K., Carfi, A., & Barouch, D. H. (2021) · Cell · doi:10.1016/j.cell.2021.02.030 · Cited by 347
Metadata
- Authors
- Chung, Y. H., Beiss, V., Fiering, S. N., & Steinmetz, N. F.
- Venue
- ACS Nano
- Publisher
- American Chemical Society (ACS)
- Published
- 2020-10-09
- Volume
- 14
- Issue
- 10
- Pages
- 12522-12537
- ISSN
- 1936-0851 (ISSN-L)
- 1936-086X
- OpenAlex
- W3091950240
- Cited by
- 346
- References
- 85
- FWCI
- 9.08
- Type
- journal article
- Language
- en
- Open access
- bronze
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