Dental Implant Therapy for a Child with X-linked Hypohidrotic Ectodermal Dysplasia— Three Decades of Managed Care
Abstract
Purpose The aim was to report on oral rehabilitation of a boy with X-linked hypohidrotic ectodermal dysplasia (XLHED) and anodontia of the mandible between ages 3 and 33 years where treatment involved dental implants and oral care management by a multidisciplinary team of specialists. Materials and methods This case history report describes the clinical management of a boy born in 1979 with XLHED and anodontia of the mandible. Two implants were successfully placed in the anterior region of the mandible in 1985. Genetic analysis later verified the diagnosis by confirming a mutation in the EDA gene. The case description was based on review of the patient records and assessment of orofacial function. Results The patient had satisfactory orofacial appearance and function throughout his youth. He is still caries-free at age 33 and has experienced only minor oral complications. Dental management began at age 3, when he received a maxillary removable dental prosthesis. At age 7, he received a mandibular implant-supported overdenture. After two more implants in the mandible and orthodontic treatment in the maxilla, his oral rehabilitation was completed at age 22 with maxillary tooth-supported and mandibular implant-supported fixed dental prostheses. Regular follow-ups provided supervision of oral hygiene, caries prevention, and prosthetic maintenance. Conclusion This long-term follow-up of a child with XLHED and anodontia in the mandible supports the use of dental implants, with cons…
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In children aged six to fourteen years, mandibular implant survival times of one up to 26 years were reported.
“In children aged six to fourteen years, mandibular implant survival times of one up to 26 years were reported.26,31,65,66,73,89”
From Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: A systematic review (2018) · cites this paper as [31]
The case report by Bergendal 1991 with a follow-up of 9 years was described again by Bergendal 2015 with a follow-up of 29 years.
“the case report by Bergendal 1991 84 with a follow-up of 9 years was described again by Bergendal 2015 31 with a follow-up of 29 years.”
From Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: A systematic review (2018) · cites this paper as [31]
One individual received an implant-supported overdenture with ball attachments in the mandibula at age 6 years.
“one individual received an implant-supported overdenture with ball attachments in the mandibula at age 6 years.31”
From Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: A systematic review (2018) · cites this paper as [31]
Renewal of partial dentures has to be expected after one to 6 years.
“and renewal of partial dentures after one to 6 years.24,31,[85][86][87][88]”
From Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: A systematic review (2018) · cites this paper as [31]
The spectrum of long-term follow-up in included reports ranges from reporting on the achievement of dental treatment without further monitoring to less frequent reports with more than a decade of monitoring.
“The spectrum ranges from reporting on the achievement of dental treatment without further monitoring to less frequent reports with more than a decade of monitoring (e.g., Bergendal et al. 2015; Fernandes et al. 2016; James and Roudsari 2019).”
From Dental Management of Genetic Dental Disorders: A Critical Review (2025) · cites this paper as Bergendal et al. 2015
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- Authors
- Bergendal, B., Bjerklin, K., Bergendal, T., & Koch, G.
- Venue
- The International Journal of Prosthodontics
- Publisher
- Quintessence Publishing
- Published
- 2015-07
- Volume
- 28
- Issue
- 4
- Pages
- 348-356
- ISSN
- 0893-2174 (ISSN-L)
- OpenAlex
- W2405185624
- Cited by
- 28
- References
- 0
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 2 · 2020: 1 · 2019: 5 · 2018: 2 · 2017: 1 · 2016: 1
- FWCI
- 0.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The International Journal of Prosthodontics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › dental development and anomalies
- Health Sciences › Dentistry › Oral Surgery › Dental Implant Techniques and Outcomes
- Health Sciences › Health Professions › Emergency Medical Services › Dental Trauma and Treatments
- Keywords
- X-linked hypohidrotic ectodermal dysplasia, dental implants, anodontia, oral rehabilitation, implant-supported overdentures, removable dentures, dental caries prevention, oral hygiene, long-term follow-up, managed care, multidisciplinary dental treatment, orofacial function
- MeSH terms
- Child, Preschool, Humans, Infant, Managed Care Programs, Dental Implants, Ectodermal Dysplasia 1, Anhidrotic
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