Oral Rehabilitation of Adult Twins With Severe Lack of Bone Due to Hypohidrotic Ectodermal Dysplasia—A 12-Month Follow-Up
Abstract
Purpose Patients with x-linked hypohidrotic ectodermal dysplasia (XLHED, OMIM 305100) often present with exceptional oral conditions, because alveolar ridges can remain severely hypotrophic due to oligo- or anodontia in the primary and/or permanent dentition. This can seriously disable a young person physically and psychologically, and lead to sociopsychological isolation. Patients and methods The oral rehabilitation of fraternal male twins with XLHED, one with severe hypodontia and the other with anodontia is described. The treatment of both patients comprised augmentation of the jaws using bicortical corticocancellous bone blocks from the medial aspect of the anterior hip, delayed implantation, and restoration of the occlusion with bar-retained overdentures. The multidisciplinary team approach included an oral and maxillofacial surgeon, a prosthodontist, and a speech therapist. Results After uneventful healing, the 12-month follow-up showed that sufficient osseointegration of the implants for optimized function was obtained by creating adequate de novo bone volume in the underdeveloped jaw regions. Full regular masticatory function was achieved, and esthetics were improved considerably in both patients. Conclusion Augmentation and implant placement prior to prosthetic rehabilitation appears to be a suitable treatment option for adult patients with XLHED.
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Primary or permanent teeth considered of little prosthetic value may be extracted in the course of rehabilitation by means of implants.
“Primary or permanent teeth considered of little prosthetic value may be extracted in the course of rehabilitation by means of implants.77,82”
From Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: A systematic review (2018) · cites this paper as [82]
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- Authors
- Kirmeier, R., Gluhak, C., Marada, P., Wegscheider, W. A., Eskici, A., & Jakse, N.
- Affiliations
- Medical University of Graz (AT)
- Corresponding author
- Jakse, Norbert
- Venue
- Journal of Oral and Maxillofacial Surgery
- Publisher
- Elsevier BV
- Published
- 2009-01
- Volume
- 67
- Issue
- 1
- Pages
- 189-194
- ISSN
- 0278-2391 (ISSN-L)
- OpenAlex
- W1976006473
- Cited by
- 21
- References
- 21
- Citations by year
- 2026: 3 · 2024: 1 · 2022: 2 · 2020: 2 · 2019: 1 · 2018: 1 · 2016: 1 · 2015: 1 · 2013: 2 · 2012: 1
- FWCI
- 0.82
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Oral and Maxillofacial Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › dental development and anomalies
- Health Sciences › Dentistry › Oral Surgery › Dental Implant Techniques and Outcomes
- Health Sciences › Medicine › Surgery › Reconstructive Facial Surgery Techniques
- Keywords
- hypohidrotic ectodermal dysplasia, X-linked hypohidrotic ectodermal dysplasia, oral rehabilitation, tooth agenesis, anodontia, bone augmentation, delayed implantation, dental implants, bar-retained overdenture, occlusal restoration, multidisciplinary team, twins
- MeSH terms
- Dental Abutments, Adolescent, Alveolar Ridge Augmentation, Anodontia, Dental Implantation, Endosseous, Denture Design, Denture Retention, Denture, Overlay, Follow-Up Studies, Humans, Jaw, Edentulous, Male, Maxillary Diseases, Oral Surgical Procedures, Preprosthetic, Twins, Dizygotic, Dental Implants, Bone Transplantation, Alveolar Bone Loss, Treatment Outcome, Dental Prosthesis, Implant-Supported, Ectodermal Dysplasia 1, Anhidrotic
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