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Cited by 1,202

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Adiponectin and Metabolic Syndrome

Matsuzawa, Yuji, Funahashi, Tohru, Kihara, Shinji, Shimomura, Iichiro·2004·Arteriosclerosis, Thrombosis, and Vascular Biology

Abstract

In this review article, the crucial roles of adipocytes in the development of so-called metabolic syndrome and vascular disease are reviewed, focusing on adipocyte-derived bioactive substances, adipocytokines. Recent progress in adipocyte biology shows that adipocytes are not merely energy-storing cells but that they secrete a variety of hormones cytokines, growth factors, and other bioactive substances. To search for novel adipocytokines by the large-scale random sequence analysis of expressed genes in adipocytes, we identified an adipose-specific collagen-like molecule, adiponectin. This novel adipocytokine has plural biofunctions, such as antidiabetic, antiatherosclerotic, and antiinflammatory functions. Adiponectin plasma levels decrease with the accumulation of visceral adipose tissue. In this review, we discuss the link of adiponectin to visceral adiposity, insulin resistance, and vascular diseases.

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Crossref · 10.1161/01.atv.0000099786.99623.ef

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Metadata

Authors
Matsuzawa, Y., Funahashi, T., Kihara, S., & Shimomura, I.
Venue
Arteriosclerosis, Thrombosis, and Vascular Biology
Published
2004-01
Volume
24
Issue
1
Pages
29-33
ISSN
  • 1079-5642 (ISSN-L)
  • 1524-4636
OpenAlex
W2147084771
Cited by
1,202
References
1
FWCI
47.53
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Adiponectin and Metabolic Syndrome. https://app.cochat.ai/papers/10.1161/01.atv.0000099786.99623.ef
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Matsuzawa, Y., Funahashi, T., Kihara, S., & Shimomura, I. (2004). Adiponectin and Metabolic Syndrome. Arteriosclerosis, Thrombosis, and Vascular Biology. https://doi.org/10.1161/01.atv.0000099786.99623.ef

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.