The DOI matches its Crossref record.
Atherogenicity and carcinogenicity of high-arsenic artesian well water. Multiple risk factors and related malignant neoplasms of blackfoot disease.
Abstract
The objective of this study was to examine multiple risk factors and correlated malignant neoplasms of blackfoot disease (BFD), a unique peripheral vascular disease related to continuous exposure to high-arsenic artesian well water. A total of 241 BFD cases, including 169 with spontaneous or surgical amputations of affected extremities, and 759 age-sex-residence-matched healthy community controls were studied to explore the risk factors of BFD. Multiple logistic regression analysis showed that artesian well water consumption, arsenic poisoning, familial history of BFD, and undernourishment were significantly associated with the development of BFD. The life-table method used to analyze cancer mortality of 789 BFD patients followed for 15 years showed a significantly higher mortality from cardiovascular diseases, peripheral vascular diseases, and cancers of bladder, skin, lung, and liver among BFD patients as compared with the general population in Taiwan or residents in the BFD-endemic area. The results imply the atherogenicity and carcinogenicity of the artesian well water in the BFD-endemic area.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Naujokas, M. F., Anderson, B., Ahsan, H., Aposhian, H. V., Graziano, J. H., Thompson, C., & Suk, W. A. (2013) · Environmental Health Perspectives · doi:10.1289/ehp.1205875 · Cited by 1,372
Cancer risks from arsenic in drinking water
Smith, A. H., Hopenhayn-Rich, C., Bates, M. N., Goeden, H. M., Hertz-Picciotto, I., Duggan, H. M., Wood, R., Kosnett, M. J., & Smith, M. T. (1992) · Environmental Health Perspectives · doi:10.1289/ehp.9297259 · Cited by 1,110
Chen, C.-J., Chen, C., Wu, M.-M., & Kuo, T.-L. (1992) · British Journal of Cancer · doi:10.1038/bjc.1992.380 · Cited by 773
Self-citationSmith, A. H., Marshall, G., Yuan, Y., Ferreccio, C., Liaw, J., von Ehrenstein, O., Steinmaus, C., Bates, M. N., & Selvin, S. (2006) · Environmental Health Perspectives · doi:10.1289/ehp.8832 · Cited by 532
Epidemiological characteristics and risk factors of hepatocellular carcinoma
CHEN, C., YU, M., & LIAW, Y. (1997) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.1997.tb00513.x · Cited by 470
Self-citation
Metadata
- Authors
- Chen, C. J., Wu, M. M., Lee, S. S., Wang, J. D., Cheng, S. H., & Wu, H. Y.
- Venue
- Arteriosclerosis: An Official Journal of the American Heart Association, Inc.
- Published
- 1988-09
- Volume
- 8
- Issue
- 5
- Pages
- 452-460
- ISSN
- 0276-5047 (ISSN-L)
- OpenAlex
- W1993338946
- Cited by
- 280
- References
- 0
- FWCI
- 2.64
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Atherogenicity and carcinogenicity of high-arsenic artesian well water. Multiple risk factors and related malignant neoplasms of blackfoot disease. https://app.cochat.ai/papers/10.1161/01.atv.8.5.452
- The paper
- Chen, C. J., Wu, M. M., Lee, S. S., Wang, J. D., Cheng, S. H., & Wu, H. Y. (1988). Atherogenicity and carcinogenicity of high-arsenic artesian well water. Multiple risk factors and related malignant neoplasms of blackfoot disease. Arteriosclerosis: An Official Journal of the American Heart Association, Inc. https://doi.org/10.1161/01.atv.8.5.452
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
