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Cited by 348Physical Activity and HealthCardiovascular and exercise physiologyCardiovascular Effects of Exercise

The DOI matches its Crossref record; 26 of the 28 references it cites were found in a registry or an index.

Relative Intensity of Physical Activity and Risk of Coronary Heart Disease

Lee, I-Min, Sesso, Howard D., Oguma, Yuko, Paffenbarger, Ralph S.·2003·Circulation
DOI 10.1161/01.cir.0000052626.63602.58
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Abstract

Background— Current recommendations prescribe at least moderate-intensity physical activity, requiring ≥3 METs (metabolic equivalents) for ≥30 minutes almost daily, generating ≈1000 kcal/wk. Defining intensity using an absolute scale in METs may be limited because it neglects variations in physical fitness: an activity requiring a particular MET value commands greater physical effort among less fit than more fit persons. It is unknown whether moderate-intensity exercise, relative to an individual’s capacity, is associated with reduced coronary heart disease (CHD) rates. Methods and Results— We followed 7337 men (mean age, 66 years) from 1988 to 1995. At baseline, men reported their actual activities and, using the Borg Scale, the perceived level of exertion when exercising (relative intensity). During follow-up, 551 men developed CHD. After multivariate adjustment, the relative risks of CHD among men who perceived their exercise exertion as “moderate,” “somewhat strong,” and “strong” or more intense were 0.86 (95% confidence interval, 0.66 to 1.13), 0.69 (0.51 to 0.94), and 0.72 (0.52 to 1.00), respectively ( P trend =0.02), compared with “weak” or less intense. This inverse association extended to men not fulfilling current recommendations, ie, expending <1000 kcal/wk in physical activity or not engaging in activities of ≥3 METs ( P trend =0.03 and 0.007, respectively). Conclusions— There is an inverse association between relative intensity of physical activity (an individual’s perceived level of exertion) and risk of CHD, even among men not satisfying current activity recommendations. Recommendations for “moderate”-intensity physical activity may need to consider individual fitness levels instead of globally prescribing activities of ≥3 METs.

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Crossref · 10.1161/01.cir.0000052626.63602.58

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Research works printed but not linked: 11

  1. 1978, Med Sci Sport, 10, vii
  2. 10.1161/circ.86.1.1617788 · DOI
  3. 10.1001/jama.1996.03540030075036 · DOI
  4. Ferguson CM Myers J Froelicher VF. Overview of exercise testing.In: Thompson PD ed. Exercise and Sports Cardiology. New York NY: McGraw-Hill; 2001: 71–109.
  5. 1974, Exerc Sport Sci Rev, 2, 131
  6. 10.1161/circ.102.9.981 · DOI
  7. 1998, Med Sci Sports Exerc, 30, 975
  8. Lee I-M Paffenbarger RS Jr. The role of physical activity in the prevention of coronary artery disease.In: Thompson PD ed. Exercise and Sports Cardiology. New York NY: McGraw-Hill; 2001: 383–401.
  9. 10.1161/circ.88.6.8252694 · DOI
  10. Food and Nutrition Board Institute of Medicine. Dietary Reference Intakes for Energy Carbohydrates Fiber Fat Protein and Amino Acids (Macronutrients). Washington DC: National Academy Press. 2002.
  11. 2001, MMWR Morb Mortal Wkly Rep, 50, 166

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Metadata

Authors
Lee, I.-M., Sesso, H. D., Oguma, Y., & Paffenbarger, R. S.
Affiliations
Brigham and Women's Hospital (US)
ORCID
Venue
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2003-03-04
Volume
107
Issue
8
Pages
1110-1116
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
DOI
10.1161/01.cir.0000052626.63602.58
OpenAlex
W2146745960
Cited by
347
References
28
Citations by year
2026: 1 · 2025: 7 · 2024: 7 · 2023: 4 · 2022: 4 · 2021: 13 · 2020: 9 · 2019: 11 · 2018: 19 · 2017: 15 · 2016: 25 · 2015: 25 · 2014: 22 · 2013: 14 · 2012: 16
FWCI
10.88
Type
journal article
Language
en
Open access
closed
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r03hl067429-02)
  • National Heart, Lung, and Blood Institute (HL-67429)
  • National Cancer Institute (R03CA091213, CA-91213)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
Keywords
physical activity intensity, coronary artery disease, perceived exertion, Borg scale, metabolic equivalents, exercise recommendations, physical fitness, men, cardiovascular risk
MeSH terms
Aged, Coronary Disease, Physical Exertion, Humans, Male, Middle Aged, Risk, Exercise

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