CoChat
Sign Up
Cited by 348Physical Activity and HealthCardiovascular and exercise physiologyCardiovascular Effects of Exercise

The DOI matches its Crossref record; 26 of the 28 references it cites were found in a registry or an index.

Relative Intensity of Physical Activity and Risk of Coronary Heart Disease

Lee, I-Min, Sesso, Howard D., Oguma, Yuko, Paffenbarger, Ralph S.·2003·Circulation
DOI 10.1161/01.cir.0000052626.63602.58
Open this paper in CoChat — free account

Abstract

Background— Current recommendations prescribe at least moderate-intensity physical activity, requiring ≥3 METs (metabolic equivalents) for ≥30 minutes almost daily, generating ≈1000 kcal/wk. Defining intensity using an absolute scale in METs may be limited because it neglects variations in physical fitness: an activity requiring a particular MET value commands greater physical effort among less fit than more fit persons. It is unknown whether moderate-intensity exercise, relative to an individual’s capacity, is associated with reduced coronary heart disease (CHD) rates. Methods and Results— We followed 7337 men (mean age, 66 years) from 1988 to 1995. At baseline, men reported their actual activities and, using the Borg Scale, the perceived level of exertion when exercising (relative intensity). During follow-up, 551 men developed CHD. After multivariate adjustment, the relative risks of CHD among men who perceived their exercise exertion as “moderate,” “somewhat strong,” and “strong” or more intense were 0.86 (95% confidence interval, 0.66 to 1.13), 0.69 (0.51 to 0.94), and 0.72 (0.52 to 1.00), respectively ( P trend =0.02), compared with “weak” or less intense. This inverse association extended to men not fulfilling current recommendations, ie, expending <1000 kcal/wk in physical activity or not engaging in activities of ≥3 METs ( P trend =0.03 and 0.007, respectively). Conclusions— There is an inverse association between relative intensity of physical activity (an individual’s perceived level of exertion) and risk of CHD, even among men not satisfying current activity recommendations. Recommendations for “moderate”-intensity physical activity may need to consider individual fitness levels instead of globally prescribing activities of ≥3 METs.

Overview

Integrity signals

Registry

Crossref · 10.1161/01.cir.0000052626.63602.58

Cites

26 of 26 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 28 references

Research works printed but not linked: 11

  1. 1978, Med Sci Sport, 10, vii
  2. 10.1161/circ.86.1.1617788 · DOI
  3. 10.1001/jama.1996.03540030075036 · DOI
  4. Ferguson CM Myers J Froelicher VF. Overview of exercise testing.In: Thompson PD ed. Exercise and Sports Cardiology. New York NY: McGraw-Hill; 2001: 71–109.
  5. 1974, Exerc Sport Sci Rev, 2, 131
  6. 10.1161/circ.102.9.981 · DOI
  7. 1998, Med Sci Sports Exerc, 30, 975
  8. Lee I-M Paffenbarger RS Jr. The role of physical activity in the prevention of coronary artery disease.In: Thompson PD ed. Exercise and Sports Cardiology. New York NY: McGraw-Hill; 2001: 383–401.
  9. 10.1161/circ.88.6.8252694 · DOI
  10. Food and Nutrition Board Institute of Medicine. Dietary Reference Intakes for Energy Carbohydrates Fiber Fat Protein and Amino Acids (Macronutrients). Washington DC: National Academy Press. 2002.
  11. 2001, MMWR Morb Mortal Wkly Rep, 50, 166

Cited by

Sorted by citations

Related

See all

Metadata

Authors
Lee, I.-M., Sesso, H. D., Oguma, Y., & Paffenbarger, R. S.
Affiliations
Brigham and Women's Hospital (US)
ORCID
Venue
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2003-03-04
Volume
107
Issue
8
Pages
1110-1116
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
DOI
10.1161/01.cir.0000052626.63602.58
OpenAlex
W2146745960
Cited by
347
References
28
Citations by year
2026: 1 · 2025: 7 · 2024: 7 · 2023: 4 · 2022: 4 · 2021: 13 · 2020: 9 · 2019: 11 · 2018: 19 · 2017: 15 · 2016: 25 · 2015: 25 · 2014: 22 · 2013: 14 · 2012: 16
FWCI
10.88
Type
journal article
Language
en
Open access
closed
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r03hl067429-02)
  • National Heart, Lung, and Blood Institute (HL-67429)
  • National Cancer Institute (R03CA091213, CA-91213)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
Keywords
physical activity intensity, coronary artery disease, perceived exertion, Borg scale, metabolic equivalents, exercise recommendations, physical fitness, men, cardiovascular risk
MeSH terms
Aged, Coronary Disease, Physical Exertion, Humans, Male, Middle Aged, Risk, Exercise

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review