Cited by 348Physical Activity and HealthCardiovascular and exercise physiologyCardiovascular Effects of Exercise

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Relative Intensity of Physical Activity and Risk of Coronary Heart Disease

Lee, I-Min, Sesso, Howard D., Oguma, Yuko, Paffenbarger, Ralph S.·2003·Circulation

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Abstract

Background— Current recommendations prescribe at least moderate-intensity physical activity, requiring ≥3 METs (metabolic equivalents) for ≥30 minutes almost daily, generating ≈1000 kcal/wk. Defining intensity using an absolute scale in METs may be limited because it neglects variations in physical fitness: an activity requiring a particular MET value commands greater physical effort among less fit than more fit persons. It is unknown whether moderate-intensity exercise, relative to an individual’s capacity, is associated with reduced coronary heart disease (CHD) rates. Methods and Results— We followed 7337 men (mean age, 66 years) from 1988 to 1995. At baseline, men reported their actual activities and, using the Borg Scale, the perceived level of exertion when exercising (relative intensity). During follow-up, 551 men developed CHD. After multivariate adjustment, the relative risks of CHD among men who perceived their exercise exertion as “moderate,” “somewhat strong,” and “strong” or more intense were 0.86 (95% confidence interval, 0.66 to 1.13), 0.69 (0.51 to 0.94), and 0.72 (0.52 to 1.00), respectively ( P trend =0.02), compared with “weak” or less intense. This inverse association extended to men not fulfilling current recommendations, ie, expending <1000 kcal/wk in physical activity or not engaging in activities of ≥3 METs ( P trend =0.03 and 0.007, respectively). Conclusions— There is an inverse association between relative intensity of physical activity (an individual’s perceived level of exertion) and risk of CHD, even among men not satisfying current activity recommendations. Recommendations for “moderate”-intensity physical activity may need to consider individual fitness levels instead of globally prescribing activities of ≥3 METs.

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Authors: Lee, I.-M., Sesso, H. D., Oguma, Y., & Paffenbarger, R. S.
Affiliations: Brigham and Women's Hospital (US)
ORCID: Lee, I-Min
Sesso, Howard D.
Oguma, Yuko
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2003-03-04
Volume: 107
Issue: 8
Pages: 1110-1116
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/01.cir.0000052626.63602.58
OpenAlex: W2146745960
Cited by: 347
References: 28
Citations by year: 2026: 1 · 2025: 7 · 2024: 7 · 2023: 4 · 2022: 4 · 2021: 13 · 2020: 9 · 2019: 11 · 2018: 19 · 2017: 15 · 2016: 25 · 2015: 25 · 2014: 22 · 2013: 14 · 2012: 16
FWCI: 10.88
Type: journal article
Language: en
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r03hl067429-02)
National Heart, Lung, and Blood Institute (HL-67429)
National Cancer Institute (R03CA091213, CA-91213)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
Keywords: physical activity intensity, coronary artery disease, perceived exertion, Borg scale, metabolic equivalents, exercise recommendations, physical fitness, men, cardiovascular risk
MeSH terms: Aged, Coronary Disease, Physical Exertion, Humans, Male, Middle Aged, Risk, Exercise

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Relative Intensity of Physical Activity and Risk of Coronary Heart Disease

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