The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.
Short-Term Clinical Outcome of Patients With Acute Pulmonary Embolism, Normal Blood Pressure, and Echocardiographic Right Ventricular Dysfunction
Open accessAbstract
Background —The role of echocardiographic right ventricular (RV) dysfunction in predicting clinical outcome in clinically stable patients with pulmonary embolism (PE) is undefined. In this study, we assessed the prevalence and clinical outcome of normotensive patients with RV dysfunction among a broad spectrum of PE patients. Methods and Results —This prospective clinical outcome study included cohort of 209 consecutive patients (age, 65±15 years) with documented PE. Acute RV dysfunction was diagnosed in the presence of ≥1 of the following: RV dilatation (without hypertrophy), paradox septal systolic motion, and Doppler evidence of pulmonary hypertension. Four groups were identified: 28 patients presenting with shock or cardiac arrest (13%), 19 hypotensive patients without shock (9%), 65 normotensive patients with echocardiographic RV dysfunction (31%), and 97 normotensive patients without RV dysfunction (47%). Among normotensive patients with RV dysfunction, 6 (10%) developed PE-related shock after admission: 3 of these patients died, and 3 were successfully treated with thrombolytic agents. In comparison, none of the 97 normotensive patients without RV dysfunction developed shock or died as a result of PE. Conclusions —A significant proportion (31%) of normotensive patients with acute PE presents with RV dysfunction; these patients with latent hemodynamic impairment have a 10% rate of PE-related shock and 5% in-hospital mortality and may require aggressive therapeutic strategies. Conversely, normotensive patients without echocardiographic RV dysfunction have a benign short-term prognosis. Thus, early detection of echocardiographic RV dysfunction is of major importance in the risk stratification of normotensive patients with acute PE.
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Citations
Cites
Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Heart Disease: A Textbook of Cardiovascular Medicine.
(1984) · Annals of Internal Medicine · doi:10.7326/0003-4819-101-3-415_3 · Cited by 4,109
Goldhaber, S. Z., Visani, L., & De Rosa, M. (1999) · The Lancet · doi:10.1016/s0140-6736(98)07534-5 · Cited by 2,870
Antithrombotic Therapy for Venous Thromboembolic Disease
Hyers, T. M., Agnelli, G., Hull, R. D., Morris, T. A., Samama, M., Tapson, V., & Weg, J. G. (2001) · Chest · doi:10.1378/chest.119.1_suppl.176s · Cited by 2,042
Self-citationThe Clinical Course of Pulmonary Embolism
Carson, J. L., Kelley, M. A., Duff, A., Weg, J. G., Fulkerson, W. J., Palevsky, H. I., Schwartz, J. S., Thompson, B. T., Popovich, J., Hobbins, T. E., et al. (1992) · New England Journal of Medicine · doi:10.1056/nejm199205073261902 · Cited by 1,039
Detection of Deep-Vein Thrombosis by Real-Time B-Mode Ultrasonography
Lensing, A. W. A., Prandoni, P., Brandjes, D., Huisman, P. M., Vigo, M., Tomasella, G., Krekt, J., ten Cate, J. W., Huisman, M. V., & Büller, H. R. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902093200602 · Cited by 875
Goldhaber, S. Z., Come, P. C., Lee, R. T., Braunwald, E., Parker, J. A., Haire, W. D., Feldstein, M. L., Miller, M., Toltzis, R., Smith, J. L., et al. (1993) · The Lancet · doi:10.1016/0140-6736(93)90274-k · Cited by 849
Regional Right Ventricular Dysfunction Detected by Echocardiography in Acute Pulmonary Embolism
McConnell, M. V., Solomon, S. D., Rayan, M. E., Come, P. C., Goldhaber, S. Z., & Lee, R. T. (1996) · The American Journal of Cardiology · doi:10.1016/s0002-9149(96)00339-6 · Cited by 747
Ribeiro, A., Lindmarker, P., Juhlin-Dannfelt, A., Johnsson, H., & Jorfeldt, L. (1997) · American Heart Journal · doi:10.1016/s0002-8703(97)70085-1 · Cited by 541
Konstantinides, S., Geibel, A., Olschewski, M., Heinrich, F., Grosser, K., Rauber, K., Iversen, S., Redecker, M., Kienast, J., Just, H., et al. (1997) · Circulation · doi:10.1161/01.cir.96.3.882 · Cited by 462
Cited by
Konstantinides, S. V., Meyer, G., Becattini, C., Bueno, H., Geersing, G.-J., Harjola, V.-P., Huisman, M. V., Humbert, M., Jennings, C. S., Jiménez, D., et al. (2020) · European Heart Journal · doi:10.1093/eurheartj/ehz405 · Cited by 4,916
2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism
Authors/Task Force Members, Konstantinides, S. V., Torbicki, A., Agnelli, G., Danchin, N., Fitzmaurice, D., Galiè, N., Gibbs, J. S. R., Huisman, M. V., Humbert, M., et al. (2014) · European Heart Journal · doi:10.1093/eurheartj/ehu283 · Cited by 3,128
Self-citationDerivation and validation of a prognostic model for pulmonary embolism
Aujesky, D., Obrosky, D. S., Stone, R. A., Auble, T. E., Perrier, A., Cornuz, J., Roy, P.-M., & Fine, M. J. (2005) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200506-862oc · Cited by 1,303
Wan, S., Quinlan, D. J., Agnelli, G., & Eikelboom, J. W. (2004) · Circulation · doi:10.1161/01.cir.0000137826.09715.9c · Cited by 616
Self-citationChronic thromboembolic pulmonary hypertension
Hoeper, M. M., Madani, M. M., Nakanishi, N., Meyer, B., Cebotari, S., & Rubin, L. J. (2014) · The Lancet Respiratory Medicine · doi:10.1016/s2213-2600(14)70089-x · Cited by 272
Metadata
- Authors
- Grifoni, S., Olivotto, I., Cecchini, P., Pieralli, F., Camaiti, A., Santoro, G., Conti, A., Agnelli, G., & Berni, G.
- Venue
- Circulation
- Published
- 2000-06-20
- Volume
- 101
- Issue
- 24
- Pages
- 2817-2822
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W1969992146
- Cited by
- 836
- References
- 18
- FWCI
- 14.32
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Grifoni, S., Olivotto, I., Cecchini, P., Pieralli, F., Camaiti, A., Santoro, G., Conti, A., Agnelli, G., & Berni, G. (2000). Short-Term Clinical Outcome of Patients With Acute Pulmonary Embolism, Normal Blood Pressure, and Echocardiographic Right Ventricular Dysfunction. Circulation. https://doi.org/10.1161/01.cir.101.24.2817
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
