The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Increased Particulate Air Pollution and the Triggering of Myocardial Infarction
Open accessAbstract
Background —Elevated concentrations of ambient particulate air pollution have been associated with increased hospital admissions for cardiovascular disease. Whether high concentrations of ambient particles can trigger the onset of acute myocardial infarction (MI), however, remains unknown. Methods and Results —We interviewed 772 patients with MI in the greater Boston area between January 1995 and May 1996 as part of the Determinants of Myocardial Infarction Onset Study. Hourly concentrations of particle mass <2.5 μm (PM 2.5 ), carbon black, and gaseous air pollutants were measured. A case-crossover approach was used to analyze the data for evidence of triggering. The risk of MI onset increased in association with elevated concentrations of fine particles in the previous 2-hour period. In addition, a delayed response associated with 24-hour average exposure 1 day before the onset of symptoms was observed. Multivariate analyses considering both time windows jointly revealed an estimated odds ratio of 1.48 associated with an increase of 25 μg/m 3 PM 2.5 during a 2-hour period before the onset and an odds ratio of 1.69 for an increase of 20 μg/m 3 PM 2.5 in the 24-hour period 1 day before the onset (95% CIs 1.09, 2.02 and 1.13, 2.34, respectively). Conclusions —The present study suggests that elevated concentrations of fine particles in the air may transiently elevate the risk of MIs within a few hours and 1 day after exposure. Further studies in other locations are needed to clarify the importance of this potentially preventable trigger of MI.
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Citations
Cites
The Case-Crossover Design: A Method for Studying Transient Effects on the Risk of Acute Events
Maclure, M. (1991) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115853 · Cited by 2,327
Mittleman, M. A., Maclure, M., Tofler, G. H., Sherwood, J. B., Goldberg, R. J., & Muller, J. E. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312023292301 · Cited by 1,431
Self-citationIncreased plasma viscosity during an air pollution episode: a link to mortality?
Peters, A., Döring, A., Wichmann, H.-E., & Koenig, W. (1997) · The Lancet · doi:10.1016/s0140-6736(97)01211-7 · Cited by 706
Self-citationPhysical Exertion as a Trigger of Acute Myocardial Infarction
Willich, S. N., Lewis, M., Lowel, H., Arntz, H.-R., Schubert, F., & Schroder, R. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312023292302 · Cited by 682
Air pollution and incidence of cardiac arrhythmia
Peters, A., Liu, E., Verrier, R. L., Schwartz, J., Gold, D. R., Mittleman, M., Baliff, J., Oh, J. A., Allen, G., Monahan, K., et al. (2000) · Epidemiology · doi:10.1097/00001648-200001000-00005 · Cited by 651
Self-citationHeart rate variability associated with particulate air pollution
Pope, C. A., Verrier, R. L., Lovett, E. G., Larson, A. C., Raizenne, M. E., Kanner, R. E., Schwartz, J., Villegas, G. M., Gold, D. R., & Dockery, D. W. (1999) · American Heart Journal · doi:10.1016/s0002-8703(99)70014-1 · Cited by 595
Control Sampling Strategies for Case-Crossover Studies: An Assessment of Relative Efficiency
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Cited by
Brook, R. D., Rajagopalan, S., Pope, C. A., Brook, J. R., Bhatnagar, A., Diez-Roux, A. V., Holguin, F., Hong, Y., Luepker, R. V., Mittleman, M. A., et al. (2010) · Circulation · doi:10.1161/cir.0b013e3181dbece1 · Cited by 6,548
Self-citationNanomaterials and nanoparticles: Sources and toxicity
Buzea, C., Pacheco, I. I., & Robbie, K. (2007) · Biointerphases · doi:10.1116/1.2815690 · Cited by 3,789
Pope, C. A., Burnett, R. T., Thurston, G. D., Thun, M. J., Calle, E. E., Krewski, D., & Godleski, J. J. (2004) · Circulation · doi:10.1161/01.cir.0000108927.80044.7f · Cited by 2,592
Passage of inhaled particles into the blood circulation in humans
Nemmar, A., Hoet, P. H. M., Vanquickenborne, B., Dinsdale, D., Thomeer, M., Hoylaerts, M. F., Vanbilloen, H., Mortelmans, L., & Nemery, B. (2002) · Circulation · doi:10.1161/hc0402.104118 · Cited by 1,719
Brook, R. D., Brook, J. R., Urch, B., Vincent, R., Rajagopalan, S., & Silverman, F. (2002) · Circulation · doi:10.1161/01.cir.0000013838.94747.64 · Cited by 845
Metadata
- Authors
- Peters, A., Dockery, D. W., Muller, J. E., & Mittleman, M. A.
- Venue
- Circulation
- Published
- 2001-06-12
- Volume
- 103
- Issue
- 23
- Pages
- 2810-2815
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2038343834
- Cited by
- 1,471
- References
- 7
- FWCI
- 35.08
- Type
- journal article
- Language
- en
- Open access
- green
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