Indirect Systolic Pressures and Pulse Waves in Arterial Occlusive Disease of the Lower Extremities
Abstract
Measurements were carried out in 146 limbs with angiographically documented arterial occlusive disease (AOD) and in 85 limbs without AOD. Ankle systolic pressure (AP) was equal to or higher than brachial systolic pressure in limbs without AOD. It was below 82% of the brachial in all limbs with complete occlusion, usually below 50% in those with multiple occlusions, and above 50% in limbs with single block. AP was below normal in 19 of 25 limbs with severe and in five of nine with mild stenosis. All limbs with complete occlusion and 14 of 16 with stenosis had abnormal pressures in the thigh. The foot-to-peak time (CT) and the width of pulse waves at half amplitude (WD) were related to heart rate in normal limbs. Considering the heart rate, the majority of limbs with AOD had abnormally prolonged CT and WD. Normal pressures and pulse waves were found together in only two limbs with stenosis and symptoms. The findings indicate that pressures and pulse waves provide a sensitive method for diagnosis and follow-up of patients with AOD.
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If the ankle-brachial index (ABI) is ≤ 0.9, then the presence of obstructive lesions in the lower extremities should be suspected.
“If the ABI is ≤ 0.9, then the presence of obstructive lesions in the lower extremities should be suspected19, 20).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [19]
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- Authors
- CARTER, S. A.
- Affiliations
- St. Boniface Hospital (CA)
- Corresponding author
- CARTER, STEFAN A.
- Venue
- Circulation
- Published
- 1968-04
- Volume
- 37
- Issue
- 4
- Pages
- 624-637
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W1994143966
- Cited by
- 308
- References
- 14
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 9 · 2023: 5 · 2022: 3 · 2021: 8 · 2020: 13 · 2019: 5 · 2018: 10 · 2017: 10 · 2016: 9 · 2015: 9 · 2014: 7 · 2013: 8 · 2012: 13
- FWCI
- 13.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Keywords
- arterial occlusive disease, lower extremity, ankle systolic pressure, pulse wave, arterial stenosis, arterial occlusion, heart rate, peripheral arterial disease diagnosis, follow-up
- MeSH terms
- Adult, Aged, Angiography, Ankle, Aorta, Abdominal, Arteries, Blood Pressure, Blood Pressure Determination, Brachial Artery, Femoral Artery, Heart Rate, Humans, Intermittent Claudication, Leg, Middle Aged, Popliteal Artery, Pulse, Vascular Diseases
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