Left Ventricular Systolic Time Intervals as Indices of Postural Circulatory Stress in Man
Abstract
The effects of graded increments of passive head-up tilt on the duration of the systolic time intervals corrected for heart rate were investigated in 15 normal subjects. Head-up tilt caused a prolongation of the pre-ejection period and a shortening of the left ventricular ejection time, while total electromechanical systole diminished minimally. The lengthening of the pre-ejection period and abbreviation of the left ventricular ejection time increased progressively with stepwise increments of head-up tilt. The application of venous occlusive tourniquets produced changes in the systolic intervals directionally similar to those observed with head-up tilt. In contrast to the normal subjects, three patients with congestive heart failure demonstrated no change in the systolic time intervals during head-up tilt. After diuresis in two of the patients with heart failure, the responses of their systolic time intervals to head-up tilt returned toward normal.
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The reduction in LVET after standing is smaller in HF patients.
“the reduction in LVET after standing is smaller in HF patients”
From Wearable Photoplethysmography for Cardiovascular Monitoring (2022) · cites this paper as [260]
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- Authors
- STAFFORD, R. W., HARRIS, W. S., & WEISSLER, A. M.
- Affiliations
- The Ohio State University (US)
- Venue
- Circulation
- Published
- 1970-03
- Volume
- 41
- Issue
- 3
- Pages
- 485-492
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2040085403
- Cited by
- 114
- References
- 26
- Citations by year
- 2025: 2 · 2022: 2 · 2021: 3 · 2020: 1 · 2019: 2 · 2017: 3 · 2016: 5 · 2015: 1 · 2014: 2 · 2013: 4 · 2012: 2
- FWCI
- 15.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- left ventricular systolic time intervals, head-up tilt, pre-ejection period, left ventricular ejection time, electromechanical systole, congestive heart failure, diuresis, heart rate correction
- MeSH terms
- Adolescent, Adult, Female, Gravitation, Heart Failure, Heart Function Tests, Heart Rate, Heart Ventricles, Humans, Male, Methods, Posture, Stress, Physiological, Time Factors, Tourniquets, Ventricular Function
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