CoChat
Sign Up
Cited by 79Cardiovascular Function and Risk FactorsHemodynamic Monitoring and TherapyCardiovascular Health and Disease Prevention

Systolic time intervals: a review of the method in the non-invasive investigation of cardiac function in health, disease and clinical pharmacology

Open access
Hassan, S, Turner, P·1983·Postgraduate Medical Journal
DOI 10.1136/pgmj.59.693.423PMC PMC2417541
Open this paper in CoChat — free accountOpen PDF

Abstract

Summary: Measurement of systolic time intervals is a valuable, non-invasive procedure to assess left ventricular performance, particularly when influenced by drugs. In this review, we discuss various factors affecting systolic time intervals, the therapeutic implications of the technique and its place among other non-invasive tests of cardiac function.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1136/pgmj.59.693.423

Cites

74 of 74 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Systolic timing intervals (STI), which measure the duration of cardiac phases, have been demonstrated as viable alternatives to stroke volume, cardiac output, and ejection fraction for assessing cardiac performance.

    “Systolic timing intervals (STI) which measure the duration of cardiac phases have been demonstrated as viable alternatives to these parameters for assessing cardiac performance.”

    From A Chest‐Conformable, Wireless Electro‐Mechanical E‐Tattoo for Measuring Multiple Cardiac Time Intervals (2023) · cites this paper as [9]

    The Introduction defines STI as durations of systolic phases, and the Validation section reports correlations with stroke volume, cardiac output, and ejection fraction, including accuracy equivalent to ejection fraction in patients with coronary artery disease. But the Conclusions call STI a helpful measure of ventricular performance that is “not competitive with other invasive or non-invasive tests”; the paper does not establish STI as a general alternative to all three parameters. Page numbers were not supplied in our copy. (LLM, conf=0.87)

    Experimental — accuracy not yet measured

  • PEP and LVET offer a convenient non-invasive method to assess left ventricular performance.

    “The PEP and LVET offer a convenient non-invasive method to assess LV performance.”

    From A Chest‐Conformable, Wireless Electro‐Mechanical E‐Tattoo for Measuring Multiple Cardiac Time Intervals (2023) · cites this paper as [9]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 8

  1. BURGESS, C.D. (1981) M.D. Thesis, University of Cape Town "The investigation of the cardiovascular effects of antidepressant drugs using non-invasive techniques."
  2. BURGESS, C.D., WADSWORTH, J. & WARRINGTON, S.J. (1979) Evaluation of some non-invasive indices of cardiovascular func- tion. British Journal of Clinical Pharmacology, 7, 436p.
  3. CROWLEY, JR. W.F., RIDGWAY, E.C., BOUGH, E.W., FRANCIS, G.S., DANIELS, G.H., KOURIDES, I.A., MYERS, G.S. & MALOOF, F. (1977) Non-invasive evaluation of cardiac function in hypothy- roidism response to gradual thyroxine replacement. New England Journal of Medicine, 2%, 1.
  4. FEIGENBAUM, H. (1980) Echocardiography. In: Heart Disease (Ed. E. Braunwald) W.B. Saunders Company, Philadelphia, London, Toronto.
  5. METZGER, C.C., CHOUGH, C.B., KROETZ, F.W. & LEONARD, J.J. (1970) true isovolumic contraction time its correlation with two external indices of ventricular performance. American Journal of Cardiology, 25, 434.
  6. RINEHART, J.T., LEWIS, R.P. & BOLCERZAK, S.P. (1974) Adriamy- cin cardiotoxicity in man. Annals of Internal Medicine, 81, 475.
  7. WEERASURIYA, K., WARRINGTON, S.J. & PATEL, L. (1981) Detec- tion of partial agonist activity of pindolol using systolic time intervals. British Journal of Clinical Pharmacology, 13, 268p.
  8. WEERASURIYA, K. (1982) Ph. D. Thesis submitted to the University of London.

Cited by

Sorted by citations

Related

Authors
Hassan, S., & Turner, P.
Affiliations
St Bartholomew's Hospital (GB)
ORCID
Turner, P
Venue
Postgraduate Medical Journal
Publisher
Oxford University Press (OUP)
Published
1983-07-01
Volume
59
Issue
693
Pages
423-434
ISSN
  • 0032-5473 (ISSN-L)
  • 1469-0756
DOI
10.1136/pgmj.59.693.423
PMC
PMC2417541
OpenAlex
W2144684046
Cited by
79
References
74
Citations by year
2026: 1 · 2025: 2 · 2024: 6 · 2023: 7 · 2022: 7 · 2021: 6 · 2020: 4 · 2019: 1 · 2018: 3 · 2017: 2 · 2016: 3 · 2015: 1 · 2012: 1
FWCI
0.92
Type
journal article
Language
en
Open access
Licence
academic.oup.com/pages/standard-publication-reuse-rights (vor)
Locations
  • Postgraduate Medical Journal (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
Keywords
systolic time intervals, left ventricular function, cardiac function assessment, noninvasive cardiac testing, clinical pharmacology
MeSH terms
Adolescent, Adult, Aged, Child, Child, Preschool, Female, Heart, Heart Function Tests, Heart Rate, Humans, Infant, Infant, Newborn, Male, Middle Aged, Myocardial Contraction, Pregnancy, Systole

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review