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Cited by 375

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Is Worrying Bad for Your Heart?: A Prospective Study of Worry and Coronary Heart Disease in the Normative Aging Study

Kubzansky, Laura D., Kawachi, Ichiro, Spiro, Avron, Weiss, Scott T., Vokonas, Pantel S., Sparrow, David·1997·Circulation

Abstract

Background Worry is an important component of anxiety, which recent work suggests is related to increased incidence of coronary heart disease (CHD). Chronic worry has also been associated with decreased heart rate variability. We hypothesized that high levels of worry may increase CHD risk. Method and Results We examined prospectively the relationship of worry with CHD incidence in the Normative Aging Study, an ongoing cohort of older men. In 1975, 1759 men free of diagnosed CHD completed a Worries Scale, indicating the extent to which they worried about each of five worry domains: social conditions, health, financial, self-definition, and aging. During 20 years of follow-up, 323 cases of incident CHD occurred: 113 cases of nonfatal myocardial infarction (MI); 86 cases of fatal CHD; and 124 cases of angina pectoris. Worry about social conditions was the domain most strongly associated with incident CHD. Compared with men reporting the lowest levels of social conditions worry, men reporting the highest levels had multivariate adjusted relative risks of 2.41 (95% CI, 1.40 to 4.13) for nonfatal MI and 1.48 (95% CI, 0.99 to 2.20) for total CHD (nonfatal MI and fatal CHD). A dose-response relation was found between level of worry and both nonfatal MI ( P for trend, .002) and total CHD ( P for trend, .04). Conclusions These results suggest that high levels of worry in specific domains may increase the risk of CHD in older men.

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Metadata

Authors
Kubzansky, L. D., Kawachi, I., Spiro, A., Weiss, S. T., Vokonas, P. S., & Sparrow, D.
Venue
Circulation
Published
1997-02-18
Volume
95
Issue
4
Pages
818-824
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
OpenAlex
W2060322525
Cited by
375
References
18
FWCI
8.83
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Is Worrying Bad for Your Heart?: A Prospective Study of Worry and Coronary Heart Disease in the Normative Aging Study. https://app.cochat.ai/papers/10.1161/01.cir.95.4.818
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Kubzansky, L. D., Kawachi, I., Spiro, A., Weiss, S. T., Vokonas, P. S., & Sparrow, D. (1997). Is Worrying Bad for Your Heart?: A Prospective Study of Worry and Coronary Heart Disease in the Normative Aging Study. Circulation. https://doi.org/10.1161/01.cir.95.4.818

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