Hostility, CHD Incidence, and Total Mortality: A 25-Year Follow-Up Study of 255 Physicians

Barefoot, John C.; Dahlstrom, Grant W.; Williams, Redford B.

doi:10.1097/00006842-198303000-00008

Cited by 873Cardiac Health and Mental HealthHeart Rate Variability and Autonomic ControlCardiovascular Health and Risk Factors

Hostility, CHD Incidence, and Total Mortality: A 25-Year Follow-Up Study of 255 Physicians

Barefoot, John C., Dahlstrom, Grant W., Williams, Redford B.·1983·Psychosomatic Medicine

DOI 10.1097/00006842-198303000-00008

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Abstract

High levels of hostility as assessed by a MMPI scale (Ho) have been found associated with increased levels of arteriographically documented coronary atherosclerosis. In this study we examined the relationship between hostility and subsequent health status in a 25-year follow-up of 255 medical students who completed the MMPI while in medical school. High Ho scores were found to be predictive of both clinical coronary disease incidence and total mortality.

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In the early 1980s investigators concluded that hostility was the primary 'toxic' component of the Type A personality.
“However, in the early 1980s investigators began to study hostility in particular [159, 160], concluding that it was the primary “toxic” component of the Type A personality [161, 162].”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [159]
Within US samples, hostility appeared to elevate risk for 25-year all-cause mortality among male medical students.
“Within US samples, hostility appeared to elevate risk for 25-year all-cause mortality among male medical students [159]”
From Personality and Longevity: Knowns, Unknowns, and Implications for Public Health and Personalized Medicine (2011) · cites this paper as [159]

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Authors: Barefoot, J. C., Dahlstrom, G. W., & Williams, R. B.
Affiliations: University of North Carolina at Chapel Hill (US)
ORCID: Williams, Redford B.
Venue: Psychosomatic Medicine
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 1983-03
Volume: 45
Issue: 1
Pages: 59-63
ISSN: 0033-3174 (ISSN-L)
DOI: 10.1097/00006842-198303000-00008
OpenAlex: W2072085129
Cited by: 866
References: 0
Citations by year: 2026: 1 · 2025: 10 · 2024: 3 · 2023: 4 · 2022: 3 · 2020: 48 · 2019: 2 · 2018: 8 · 2017: 4 · 2016: 11 · 2015: 6 · 2014: 19 · 2013: 14 · 2012: 20
FWCI: 20.07
Type: journal article
Language: en
Open access: closed
Locations: Psychosomatic Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords: hostility, coronary heart disease incidence, all-cause mortality, coronary artery disease, medical students, long-term follow-up, risk prediction
MeSH terms: Adult, Angina Pectoris, Coronary Disease, Follow-Up Studies, Hostility, Humans, Male, Middle Aged, MMPI, Myocardial Infarction, Personality, Physicians

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Hostility, CHD Incidence, and Total Mortality: A 25-Year Follow-Up Study of 255 Physicians

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