Cited by 262Blood Pressure and Hypertension StudiesCardiovascular Function and Risk FactorsSodium Intake and Health

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Impact of Obesity on 24-Hour Ambulatory Blood Pressure and Hypertension

Kotsis, Vasilios, Stabouli, Stella, Bouldin, Marshall, Low, Annette, Toumanidis, Savvas, Zakopoulos, Nikos·2005·Hypertension

DOI 10.1161/01.hyp.0000158261.86674.8e

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Abstract

The purpose of the present study was to determine the relationship between body mass index (BMI) and parameters derived from 24-hour ambulatory blood pressure monitoring including mean 24-hour daytime and nighttime systolic and diastolic blood pressures, 24-hour daytime and nighttime pulse pressure, mean 24-hour daytime and nighttime heart rate, dipping and nondipping status. 3216 outpatient subjects who visited our hypertension center and were never treated with antihypertensive medication underwent 24-hour blood pressure monitoring. BMI was significantly correlated with clinic systolic and diastolic blood pressures. Significant correlations were also found between BMI and mean 24-hour daytime and nighttime systolic blood pressure, 24-hour daytime and nighttime pulse pressure, and mean 24-hour daytime and nighttime heart rate. In multivariate regression analysis, clinic systolic, diastolic blood pressure, mean 24-hour systolic blood pressure, 24-hour pulse pressure, and high-density lipoprotein were independently correlated with BMI. The incidence of white coat hypertension was higher in overweight and obese patients than in normal weight subjects. Confirmed ambulatory blood pressure hypertension was also found to be higher in overweight and obese individuals compared with normal weight subjects. Our data also highlight the higher incidence of nondipping status in obesity. These findings suggest that obese patients had increased ambulatory blood pressure parameters and altered circadian blood pressure rhythm with increased prevalence of nondipping status.

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Authors: Kotsis, V., Stabouli, S., Bouldin, M., Low, A., Toumanidis, S., & Zakopoulos, N.
Affiliations: National and Kapodistrian University of Athens (GR)
ORCID: Kotsis, Vasilios
Stabouli, Stella
Toumanidis, Savvas
Venue: Hypertension
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2005-04
Volume: 45
Issue: 4
Pages: 602-607
ISSN: 0194-911X (ISSN-L)
1524-4563
DOI: 10.1161/01.hyp.0000158261.86674.8e
OpenAlex: W2061864688
Cited by: 262
References: 47
Citations by year: 2026: 5 · 2025: 6 · 2024: 10 · 2023: 14 · 2022: 10 · 2021: 22 · 2020: 7 · 2019: 13 · 2018: 9 · 2017: 9 · 2016: 16 · 2015: 15 · 2014: 11 · 2013: 10 · 2012: 9
FWCI: 10.03
Type: journal article
Language: en
Open access: closed
Locations: Hypertension (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Health Sciences › Nursing › Nutrition and Dietetics › Sodium Intake and Health
Keywords: obesity, body mass index, ambulatory blood pressure monitoring, pulse pressure, heart rate, circadian blood pressure rhythm, non-dipping blood pressure, white coat hypertension, overweight, HDL cholesterol
MeSH terms: Adult, Aged, Blood Pressure, Circadian Rhythm, Female, Heart Rate, Humans, Hypertension, Lipoproteins, HDL, Male, Middle Aged, Obesity, Body Mass Index, Multivariate Analysis, Blood Pressure Monitoring, Ambulatory

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Impact of Obesity on 24-Hour Ambulatory Blood Pressure and Hypertension

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