The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Changes in autonomic regulation induced by physical training in mild hypertension.
Open accessAbstract
The adaptive effects of physical training on cardiovascular control mechanisms were studied in 11 subjects with mild hypertension. In these subjects we assessed the gain of the heart period-systolic arterial pressure relationship in the unfit and the fit state by using 1) an open loop approach, whereby the gain is expressed by the slope of the regression of heart period as a function of systolic arterial pressure, during a phenylephrine-induced pressure rise and 2) a closed loop approach with proper simplification, whereby the gain is expressed by the index alpha, obtained through simultaneous spectral analysis of the spontaneous variabilities of heart period and systolic arterial pressure. Both methods indicated that training significantly increased the gain of the relationship between heart period and systolic arterial pressure at rest and reduced arterial pressure and increased heart period significantly. This gain was drastically reduced during bicycle exercise both in the unfit and fit state. In a second group of normotensive (n = 7; systolic pressure, 133 +/- 3 mm Hg) and hypertensive (n = 7; systolic pressure, 180 +/- 10 mm Hg) subjects undergoing 24-hour diagnostic continuous electrocardiographic and high fidelity arterial pressure monitoring, the index alpha was significantly reduced in the hypertensive group at rest. Furthermore, when analyzed continuously over the entire 24-hour period, this index underwent minute-to-minute changes with lower values during the day and higher values during the night. We propose the index alpha as a quantitative indicator of the changes in the gain of baroreceptor mechanisms occurring with physical training in mild hypertension and during a 24-hour period in ambulatory subjects.
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Cites
Akselrod, S., Gordon, D., Ubel, F. A., Shannon, D. C., Berger, A. C., & Cohen, R. J. (1981) · Science · doi:10.1126/science.6166045 · Cited by 5,079
Pagani, M., Lombardi, F., Guzzetti, S., Rimoldi, O., Furlan, R., Pizzinelli, P., Sandrone, G., Malfatto, G., Dell'Orto, S., & Piccaluga, E. (1986) · Circulation Research · doi:10.1161/01.res.59.2.178 · Cited by 4,130
Self-citationAssessment of autonomic function in humans by heart rate spectral analysis
Pomeranz, B., Macaulay, R. J., Caudill, M. A., Kutz, I., Adam, D., Gordon, D., Kilborn, K. M., Barger, A. C., Shannon, D. C., Cohen, R. J., et al. (1985) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1985.248.1.h151 · Cited by 2,876
Statistical Methods in Medical Research
Lachenbruch, P. A. (1972) · Technometrics · doi:10.1080/00401706.1972.10488903 · Cited by 1,703
Hemodynamic regulation: investigation by spectral analysis
Akselrod, S., Gordon, D., Madwed, J. B., Snidman, N. C., Shannon, D. C., & Cohen, R. J. (1985) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1985.249.4.h867 · Cited by 1,292
SMYTH, H. S., SLEIGHT, P., & PICKERING, G. W. (1969) · Circulation Research · doi:10.1161/01.res.24.1.109 · Cited by 1,282
Self-citationThe Fitting of Time-Series Models
Durbin, J. (1960) · Revue de l'Institut International de Statistique / Review of the International Statistical Institute · doi:10.2307/1401322 · Cited by 1,056
Effect of Age and High Blood Pressure on Barorefiex Sensitivity in Man
Gribbin, B., Pickering, T. G., Sleight, P., & Peto, R. (1971) · Circulation Research · doi:10.1161/01.res.29.4.424 · Cited by 1,038
Self-citationBlood pressure and heart rate variabilities in normotensive and hypertensive human beings.
Mancia, G., Ferrari, A., Gregorini, L., Parati, G., Pomidossi, G., Bertinieri, G., Grassi, G., di Rienzo, M., Pedotti, A., & Zanchetti, A. (1983) · Circulation Research · doi:10.1161/01.res.53.1.96 · Cited by 776
Assessment of baroreceptor reflex sensitivity by means of spectral analysis.
Robbe, H. W., Mulder, L. J., Rüddel, H., Langewitz, W. A., Veldman, J. B., & Mulder, G. (1987) · Hypertension · doi:10.1161/01.hyp.10.5.538 · Cited by 746
Cited by
Cardiovascular neural regulation explored in the frequency domain.
Malliani, A., Pagani, M., Lombardi, F., & Cerutti, S. (1991) · Circulation · doi:10.1161/01.cir.84.2.482 · Cited by 3,569
Self-citationSympathetic-Nerve Activity during Sleep in Normal Subjects
Somers, V. K., Dyken, M. E., Mark, A. L., & Abboud, F. M. (1993) · New England Journal of Medicine · doi:10.1056/nejm199302043280502 · Cited by 1,574
Self-citationParati, G., Saul, J. P., Di Rienzo, M., & Mancia, G. (1995) · Hypertension · doi:10.1161/01.hyp.25.6.1276 · Cited by 849
Baroreflex Sensitivity: Measurement and Clinical Implications
La Rovere, M. T., Pinna, G. D., & Raczak, G. (2008) · Annals of Noninvasive Electrocardiology · doi:10.1111/j.1542-474x.2008.00219.x · Cited by 659
Brook, R. D., Appel, L. J., Rubenfire, M., Ogedegbe, G., Bisognano, J. D., Elliott, W. J., Fuchs, F. D., Hughes, J. W., Lackland, D. T., Staffileno, B. A., et al. (2013) · Hypertension · doi:10.1161/hyp.0b013e318293645f · Cited by 573
Metadata
- Authors
- Pagani, M., Somers, V, Furlan, R., Dell'Orto, S., Conway, J., Baselli, G., Cerutti, S., Sleight, P., & Malliani, A.
- Venue
- Hypertension
- Published
- 1988-12
- Volume
- 12
- Issue
- 6
- Pages
- 600-610
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W2059590433
- Cited by
- 745
- References
- 40
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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