The DOI matches its Crossref record; 48 of the 49 references it cites were found in a registry or an index.
The vasodilator action of insulin. Implications for the insulin hypothesis of hypertension.
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“Thus, in normal humans, hyperinsulinemia increases sympathetic nerve activity, but does not increase blood pressure because the sympathetic activation is offset by a direct vasodilator action of insulin82”
From The Sympathetic Nervous System Alterations in Human Hypertension (2015) · cites this paper as [82]
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Citations
Cites
Role of Insulin Resistance in Human Disease
Reaven, G. M. (1988) · Diabetes · doi:10.2337/diab.37.12.1595 · Cited by 12,154
Insulin Resistance in Essential Hypertension
Ferrannini, E., Buzzigoli, G., Bonadonna, R., Giorico, M. A., Oleggini, M., Graziadei, L., Pedrinelli, R., Brandi, L., & Bevilacqua, S. (1987) · New England Journal of Medicine · doi:10.1056/nejm198708063170605 · Cited by 2,344
Hyperinsulinemia. A link between hypertension obesity and glucose intolerance.
Modan, M., Halkin, H., Almog, S., Lusky, A., Eshkol, A., Shefi, M., Shitrit, A., & Fuchs, Z. (1985) · Journal of Clinical Investigation · doi:10.1172/jci111776 · Cited by 1,465
Effect of Insulin and Glucose Infusions on Sympathetic Nervous System Activity in Normal Man
Rowe, J. W., Young, J. B., Minaker, K. L., Stevens, A. L., Pallotta, J., & Landsberg, L. (1981) · Diabetes · doi:10.2337/diab.30.3.219 · Cited by 1,143
The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man.
DeFronzo, R. A., Cooke, C. R., Andres, R., Faloona, G. R., & Davis, P. J. (1975) · Journal of Clinical Investigation · doi:10.1172/jci107996 · Cited by 1,104
Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans.
Anderson, E. A., Hoffman, R. P., Balon, T. W., Sinkey, C. A., & Mark, A. L. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115260 · Cited by 1,075
Self-citationLaakso, M., Edelman, S. V., Brechtel, G., & Baron, A. D. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114644 · Cited by 930
Impaired Insulin-Mediated Skeletal Muscle Blood Flow in Patients With NIDDM
Laakso, M., Edelman, S. V., Brechtel, G., & Baron, A. D. (1992) · Diabetes · doi:10.2337/diab.41.9.1076 · Cited by 470
Resistance to Insulin-Stimulated-Glucose Uptake in Patients with Hypertension*
Shen, D. C., Shieh, S.-M., Fuh, M. M.-T., WU, D.-A., Chen, Y. I., & Reaven, G. M. (1988) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-66-3-580 · Cited by 420
Effect of insulin on the proliferation of cultured primate arterial smooth muscle cells.
Stout, R. W., Bierman, E. L., & Ross, R. (1975) · Circulation Research · doi:10.1161/01.res.36.2.319 · Cited by 405
Cited by
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Reaven, G. M., Lithell, H., & Landsberg, L. (1996) · New England Journal of Medicine · doi:10.1056/nejm199602083340607 · Cited by 1,435
Carretero, O. A., & Oparil, S. (2000) · Circulation · doi:10.1161/01.cir.101.3.329 · Cited by 1,155
Vickers, M. H., Breier, B. H., Cutfield, W. S., Hofman, P. L., & Gluckman, P. D. (2000) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2000.279.1.e83 · Cited by 999
The Sympathetic Nervous System Alterations in Human Hypertension
Grassi, G., Mark, A., & Esler, M. (2015) · Circulation Research · doi:10.1161/circresaha.116.303604 · Cited by 616
Self-citationThe Metabolic Syndrome in Overweight Hispanic Youth and the Role of Insulin Sensitivity
Cruz, M. L., Weigensberg, M. J., Huang, T. T. ‐., Ball, G. D. C., Shaibi, G. Q., & Goran, M. I. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031188 · Cited by 601
Metadata
- Authors
- Anderson, E. A., & Mark, A. L.
- Venue
- Hypertension
- Published
- 1993-02
- Volume
- 21
- Issue
- 2
- Pages
- 136-141
- ISSN
- 0194-911X (ISSN-L)
- 1524-4563
- OpenAlex
- W1832341580
- Cited by
- 242
- References
- 49
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 1 · 2023: 1 · 2020: 2 · 2018: 4 · 2017: 1 · 2016: 2 · 2015: 3 · 2014: 1 · 2013: 3 · 2012: 2
- FWCI
- 21.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Department of Veterans Affairs
- National Institutes of Health (14388, 5p50hl044546-05, 5r29hl043514-05, HL14388)
- National Heart, Lung, and Blood Institute (HL-43514, HL-14388, HL-44546, P01HL014388)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- insulin, vasodilation, insulin resistance, hypertension pathogenesis
- MeSH terms
- Animals, Blood Pressure, Humans, Hyperinsulinism, Hypertension, Insulin, Insulin Resistance, Sympathetic Nervous System, Vasodilation, Genetic Predisposition to Disease
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