The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Plasma Adiponectin Levels and Five-Year Survival After First-Ever Ischemic Stroke
Abstract
Background and Purpose— This study aimed to investigate the association between plasma adiponectin levels and 5-year survival after first-ever ischemic stroke. Methods— Plasma adiponectin measured within 24 hours after first-ever ischemic stroke was related to 5-year outcome. The Kaplan–Meier technique was applied in survival analysis, and the Cox proportional hazards model was used to evaluate the relationship between risk factors and prognosis. Results— The probabilities of death were 92.8%, 52.5%, and 10.5% ( P <0.001) for patients stratified according to tertiles of adiponectin (<4 μg/mL, 4 to 7 μg/mL, and >7 μg/mL, respectively). The relative risk of death was 8.1 (95% CI, 3.1, 24.5; P <0.001) for individuals with adiponectin levels in the lowest tertile compared with the upper tertile. Adiponectin <4 μg/mL (hazard ratio [HR], 5.2; 95% CI, 2.1, 18.4; P <0.001), score >15 in the National Institutes of Health Stroke Scale (HR, 3.6; 95% CI, 1.7, 15.9; P <0.001), and coronary heart disease (HR, 2.9; 95% CI, 1.5, 12.3; P <0.001) were independently associated with mortality. Conclusions— Low plasma adiponectin is related to an increased risk of 5-year mortality after first-ever ischemic stroke, independently of other adverse predictors.
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“In another case, low plasma adiponectin was related to an increased risk of 5-yr mortality after first-ever ischemic stroke (94).”
From Cardiac remodeling in obesity (2008) · cites this paper as [94]
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Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity
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Plasma Concentrations of a Novel, Adipose-Specific Protein, Adiponectin, in Type 2 Diabetic Patients
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Plasma Adiponectin Levels and Risk of Myocardial Infarction in Men
Pischon, T. (2004) · JAMA · doi:10.1001/jama.291.14.1730 · Cited by 1,782
Cnop, M., Havel, P. J., Utzschneider, K. M., Carr, D. B., Sinha, M. K., Boyko, E. J., Retzlaff, B. M., Knopp, R. H., Brunzell, J. D., & Kahn, S. E. (2003) · Diabetologia · doi:10.1007/s00125-003-1074-z · Cited by 1,483
Association of Hypoadiponectinemia With Coronary Artery Disease in Men
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The role of the novel adipocyte-derived hormone adiponectin in human disease
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Abel, E. D., Litwin, S. E., & Sweeney, G. (2008) · Physiological Reviews · doi:10.1152/physrev.00017.2007 · Cited by 736
Leptin and Cardiovascular Disease
Koh, K. K., Park, S. M., & Quon, M. J. (2008) · Circulation · doi:10.1161/circulationaha.107.741645 · Cited by 481
Blood Markers for the Prognosis of Ischemic Stroke
Whiteley, W. N., Chong, W. L., Sengupta, A., & Sandercock, P. A. (2009) · Stroke · doi:10.1161/strokeaha.108.528752 · Cited by 290
The Harms and Benefits of Inflammatory and Immune Responses in Vascular Disease
Chamorro, Á., & Hallenbeck, J. M. (2006) · Stroke · doi:10.1161/01.str.0000200561.69611.f8 · Cited by 282
Adiponectin and Cardiovascular Disease
Han, S. H., Quon, M. J., Kim, J., & Koh, K. K. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.08.061 · Cited by 276
Metadata
- Authors
- Efstathiou, S. P., Tsioulos, D. I., Tsiakou, A. G., Gratsias, Y. E., Pefanis, A. V., & Mountokalakis, T. D.
- Affiliations
- Metropolitan Hospital (GR)
- Venue
- Stroke
- Published
- 2005-09
- Volume
- 36
- Issue
- 9
- Pages
- 1915-1919
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W2088840838
- Cited by
- 162
- References
- 36
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 1 · 2023: 5 · 2022: 5 · 2021: 7 · 2020: 6 · 2019: 8 · 2018: 9 · 2017: 8 · 2016: 6 · 2015: 6 · 2014: 3 · 2013: 8 · 2012: 7
- FWCI
- 10.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Stroke (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Acute Ischemic Stroke Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Keywords
- adiponectin, ischemic stroke, mortality, prognostic factors, plasma adiponectin levels, stroke severity, NIHSS, coronary artery disease, five-year survival
- MeSH terms
- Aged, Brain Ischemia, Female, Follow-Up Studies, Humans, Inflammation, Male, Middle Aged, Prognosis, Risk, Risk Factors, Time Factors, Vascular Diseases, Multivariate Analysis, Proportional Hazards Models, Odds Ratio, Treatment Outcome, Stroke, Adiponectin
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