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Regional Cerebral Blood Flow Estimated by 133 Xenon Inhalation
Open accessAbstract
A method is described for estimating the clearance rate and fractional blood flow of the fast (gray matter) compartment of the brain from the first ten minutes of 133 Xe clearance curves, following a one-minute inhalation. Computer-simulated data were used to test the adequacy of the two-compartmental model employed, and to evaluate the stability of the parameters in the presence of random noise. A comparison was made between this approach and the previously reported three-compartmental analysis. Regional cerebral blood flow data were obtained on 48 young control subjects and 20 elderly demented patients. Hemispheral regional, and test-retest variations were determined, as well as differences between the groups.
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Cited by
Obrist, W. D., Langfitt, T. W., Jaggi, J. L., Cruz, J., & Gennarelli, T. A. (1984) · Journal of Neurosurgery · doi:10.3171/jns.1984.61.2.0241 · Cited by 835
Self-citationFazekas, F., Niederkorn, K., Schmidt, R., Offenbacher, H., Horner, S., Bertha, G., & Lechner, H. (1988) · Stroke · doi:10.1161/01.str.19.10.1285 · Cited by 455
Sex and Handedness Differences in Cerebral Blood Flow During Rest and Cognitive Activity
Gur, R. C., Gur, R. E., Obrist, W. D., Hungerbuhler, J. P., Younkin, D., Rosen, A. D., Skolnick, B. E., & Reivich, M. (1982) · Science · doi:10.1126/science.7089587 · Cited by 438
Self-citationThe capillary network: A link between IVIM and classical perfusion
Bihan, D. L., & Turner, R. (1992) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910270116 · Cited by 423
Berman, K. F. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800020032005 · Cited by 417
Metadata
- Authors
- OBRIST, W. D., THOMPSON, H. K., WANG, H. S., & WILKINSON, W. E.
- Venue
- Stroke
- Published
- 1975-05
- Volume
- 6
- Issue
- 3
- Pages
- 245-256
- ISSN
- 0039-2499 (ISSN-L)
- 1524-4628
- OpenAlex
- W2027217568
- Cited by
- 859
- References
- 0
- FWCI
- 22.13
- Type
- journal article
- Language
- en
- Open access
- bronze
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- OBRIST, W. D., THOMPSON, H. K., WANG, H. S., & WILKINSON, W. E. (1975). Regional Cerebral Blood Flow Estimated by 133 Xenon Inhalation. Stroke. https://doi.org/10.1161/01.str.6.3.245
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.