The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Engineering Robust and Functional Vascular Networks In Vivo With Human Adult and Cord Blood–Derived Progenitor Cells
Open accessAbstract
The success of therapeutic vascularization and tissue engineering will rely on our ability to create vascular networks using human cells that can be obtained readily, can be expanded safely ex vivo, and can produce robust vasculogenic activity in vivo. Here we describe the formation of functional microvascular beds in immunodeficient mice by coimplantation of human endothelial and mesenchymal progenitor cells isolated from blood and bone marrow. Evaluation of implants after 1 week revealed an extensive network of human blood vessels containing erythrocytes, indicating the rapid formation of functional anastomoses within the host vasculature. The implanted endothelial progenitor cells were restricted to the luminal aspect of the vessels; mesenchymal progenitor cells were adjacent to lumens, confirming their role as perivascular cells. Importantly, the engineered vascular networks remained patent at 4 weeks in vivo. This rapid formation of long-lasting microvascular networks by postnatal progenitor cells obtained from noninvasive sources constitutes an important step forward in the development of clinical strategies for tissue vascularization.
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Cites
Multilineage potential of adult human mesenchymal stem cells
Pittenger, M. F., Mackay, A. M., Beck, S. C., Jaiswal, R. K., Douglas, R., Mosca, J. D., Moorman, M. A., Simonetti, D. W., Craig, S., & Marshak, D. R. (1999) · Science · doi:10.1126/science.284.5411.143 · Cited by 21,052
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., & Isner, J. M. (1997) · Science · doi:10.1126/science.275.5302.964 · Cited by 8,725
Creation of long-lasting blood vessels
Koike, N., Fukumura, D., Gralla, O., Au, P., Schechner, J. S., & Jain, R. K. (2004) · Nature · doi:10.1038/428138a · Cited by 701
Paracrine Regulation of Angiogenesis and Adipocyte Differentiation During In Vivo Adipogenesis
Fukumura, D., Ushiyama, A., Duda, D. G., Xu, L., Tam, J., Krishna, V., Chatterjee, K., Garkavtsev, I., & Jain, R. K. (2003) · Circulation Research · doi:10.1161/01.res.0000099243.20096.fa · Cited by 365
Cited by
Dudley, A. C. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006536 · Cited by 424
Geometric control of vascular networks to enhance engineered tissue integration and function
Baranski, J. D., Chaturvedi, R. R., Stevens, K. R., Eyckmans, J., Carvalho, B., Solorzano, R. D., Yang, M. T., Miller, J. S., Bhatia, S. N., & Chen, C. S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1217796110 · Cited by 267
Lin, R.-Z., Moreno-Luna, R., Li, D., Jaminet, S.-C., Greene, A. K., & Melero-Martin, J. M. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1405388111 · Cited by 161
Self-citationStem cell sources for vascular tissue engineering and regeneration
Bajpai, V. K., & Andreadis, S. T. (2012) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2011.0264 · Cited by 95
Greenberger, S., Yuan, S., Walsh, L. A., Boscolo, E., Kang, K.-T., Matthews, B., Mulliken, J. B., & Bischoff, J. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2011.300 · Cited by 94
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Metadata
- Authors
- Melero-Martin, J. M., De Obaldia, M. E., Kang, S.-Y., Khan, Z. A., Yuan, L., Oettgen, P., & Bischoff, J.
- Venue
- Circulation Research
- Published
- 2008-07-18
- Volume
- 103
- Issue
- 2
- Pages
- 194-202
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- OpenAlex
- W2152442991
- Cited by
- 488
- References
- 4
- FWCI
- 14.15
- Type
- journal article
- Language
- en
- Open access
- green
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- Melero-Martin, J. M., De Obaldia, M. E., Kang, S.-Y., Khan, Z. A., Yuan, L., Oettgen, P., & Bischoff, J. (2008). Engineering Robust and Functional Vascular Networks In Vivo With Human Adult and Cord Blood–Derived Progenitor Cells. Circulation Research. https://doi.org/10.1161/circresaha.108.178590
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
