The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Mitochondrial Oxidative Stress Mediates Angiotensin II–Induced Cardiac Hypertrophy and Gαq Overexpression–Induced Heart Failure
Open accessAbstract
Rationale: Mitochondrial dysfunction has been implicated in several cardiovascular diseases; however, the roles of mitochondrial oxidative stress and DNA damage in hypertensive cardiomyopathy are not well understood. Objective: We evaluated the contribution of mitochondrial reactive oxygen species (ROS) to cardiac hypertrophy and failure by using genetic mouse models overexpressing catalase targeted to mitochondria and to peroxisomes. Methods and Results: Angiotensin II increases mitochondrial ROS in cardiomyocytes, concomitant with increased mitochondrial protein carbonyls, mitochondrial DNA deletions, increased autophagy and signaling for mitochondrial biogenesis in hearts of angiotensin II–treated mice. The causal role of mitochondrial ROS in angiotensin II–induced cardiomyopathy is shown by the observation that mice that overexpress catalase targeted to mitochondria, but not mice that overexpress wild-type peroxisomal catalase, are resistant to cardiac hypertrophy, fibrosis and mitochondrial damage induced by angiotensin II, as well as heart failure induced by overexpression of Gαq. Furthermore, primary damage to mitochondrial DNA, induced by zidovudine administration or homozygous mutation of mitochondrial polymerase γ, is also shown to contribute directly to the development of cardiac hypertrophy, fibrosis and failure. Conclusions: These data indicate the critical role of mitochondrial ROS in cardiac hypertrophy and failure and support the potential use of mitochondrial-targeted antioxidants for prevention and treatment of hypertensive cardiomyopathy.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Various signs of increased oxidative stress have been reported in various cardiovascular-related diagnoses such as heart failure (Dai et al. 2012), ventricular hypertrophy (Dai et al. 2011), myocardial infarction (Merabet et al. 2012), diabetes (Anderson et al. 2009) and other conditions.”
From Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging (2023) · cites this paper as Dai et al. 2011
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Methods in Mammalian Autophagy Research
Mizushima, N., Yoshimori, T., & Levine, B. (2010) · Cell · doi:10.1016/j.cell.2010.01.028 · Cited by 4,497
Mitochondria, Oxidants, and Aging
Balaban, R. S., Nemoto, S., & Finkel, T. (2005) · Cell · doi:10.1016/j.cell.2005.02.001 · Cited by 4,388
Premature ageing in mice expressing defective mitochondrial DNA polymerase
Trifunovic, A., Wredenberg, A., Falkenberg, M., Spelbrink, J. N., Rovio, A. T., Bruder, C. E., Bohlooly-Y, M., Gidlöf, S., Oldfors, A., Wibom, R., et al. (2004) · Nature · doi:10.1038/nature02517 · Cited by 2,734
St-Pierre, J., Drori, S., Uldry, M., Silvaggi, J. M., Rhee, J., Jäger, S., Handschin, C., Zheng, K., Lin, J., Yang, W., et al. (2006) · Cell · doi:10.1016/j.cell.2006.09.024 · Cited by 2,233
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
Kujoth, G. C., Hiona, A., Pugh, T. D., Someya, S., Panzer, K., Wohlgemuth, S. E., Hofer, T., Seo, A. Y., Sullivan, R., Jobling, W. A., et al. (2005) · Science · doi:10.1126/science.1112125 · Cited by 2,165
Self-citationExtension of murine life span by overexpression of catalase targeted to mitochondria
Schriner, S. E., Linford, N. J., Martin, G. M., Treuting, P., Ogburn, C. E., Emond, M., Coskun, P. E., Ladiges, W., Wolf, N., Van Remmen, H., et al. (2005) · Science · doi:10.1126/science.1106653 · Cited by 1,724
Self-citationMolecular Mechanisms of Human Hypertension
Lifton, R. P., Gharavi, A. G., & Geller, D. S. (2001) · Cell · doi:10.1016/s0092-8674(01)00241-0 · Cited by 1,686
Mitochondrial Respiratory-Chain Diseases
DiMauro, S., & Schon, E. A. (2003) · New England Journal of Medicine · doi:10.1056/nejmra022567 · Cited by 1,672
Anderson, E. J., Lustig, M. E., Boyle, K. E., Woodlief, T. L., Kane, D. A., Lin, C.-T., Price, J. W., Kang, L., Rabinovitch, P. S., Szeto, H. H., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci37048 · Cited by 1,253
Self-citationTranscriptional control of mitochondrial biogenesis: the central role of PGC-1
Ventura-Clapier, R., Garnier, A., & Veksler, V. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn098 · Cited by 932
Cited by
Sorted by citations
Items 401–500 of 526
Tian, F., & Zhang, Y. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.636553 · Cited by 10
RetractedZhang, Y., Yan, H., Guang, G.-C., & Deng, Z.-R. (2017) · Clinical and Experimental Hypertension · doi:10.1080/10641963.2016.1226893 · Cited by 10
Harada, T., Kondo, H., Nakamura, K., He, Y., Goto, S., Takahashi, M., Yamasaki, H., Matsuda, N., Takano, M., Abe, I., et al. (2025) · Circulation Journal · doi:10.1253/circj.cj-24-0659 · Cited by 9
Modulation of PPAR ‐α and PPAR ‐γ Influences Cardiomyocyte Growth and Cardiac Remodeling
Xuan, Q., Li, J., Feng, Z., Zhu, L., Jiang, T., Li, H., Liu, M., Qian, X., & Ma, X. (2025) · IUBMB Life · doi:10.1002/iub.70035 · Cited by 9
Iron Deficiency Anemia-Induced Cardiomyopathy With Congestive Heart Failure
Miura, S., Naya, M., & Yamashita, T. (2020) · JACC Case Reports · doi:10.1016/j.jaccas.2020.07.051 · Cited by 9
Chen, X., Ashraf, S., Ashraf, N., & Harmancey, R. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.121.022556 · Cited by 10
Autophagy, Oxidative Stress, and Redox Regulation
Ma, J., Yang, L., Ren, J. T., & Yang, J. Z. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805253-2.00020-1 · Cited by 10
Heart Failure Highlights in 2011
Westenbrink, B. D., Damman, K., Rienstra, M., Maass, A. H., & van der Meer, P. (2012) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfs121 · Cited by 8
Li, S., Qian, X., Fang, G., Deng, Y., Yang, F., Qiu, C., Yang, Y., & Lan, C. (2023) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2023.166859 · Cited by 9
Circ-0001283 Aggravates Cardiac Hypertrophy by Targeting Myosin Light Chain 3 Protein
Wang, W., Chen, L., Zhao, Y., Zhang, S., & Zhou, X. (2025) · Research · doi:10.34133/research.0626 · Cited by 8
Bhullar, S. K., & Dhalla, N. S. (2023) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2023-0226 · Cited by 9
In vitro effects of exercise on the heart
Youtz, D. J., Isfort, M. C., Eichenseer, C. M., Nelin, T. D., & Wold, L. E. (2014) · Life Sciences · doi:10.1016/j.lfs.2014.08.015 · Cited by 8
Effects and Mechanism of Action of Ligustrazine on Isoprenaline-Induced Cardiomyocyte Hypertrophy
Ji, X. X., Song, X., Qian, W., Yu, X. L., & Zhu, J. Y. (2014) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-014-0086-2 · Cited by 8
Redox Regulation of the Microcirculation
Kadlec, A. O., & Gutterman, D. D. (2019) · Comprehensive physiology · doi:10.1002/cphy.c180039 · Cited by 10
Autophagy: Are Amino Acid Signals Dependent on the mTORC1 Pathway or Independent?
Jin, C., Zhu, M., Ye, J., Song, Z., Zheng, C., & Chen, W. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46080519 · Cited by 10
Szyller, J., Antoniak, R., Wadowska, K., Bil‐Lula, I., Hrymniak, B., Banasiak, W., & Jagielski, D. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1289587 · Cited by 7
Cardiovascular Disease in Aging and the Role of Oxidative Stress
Alzaïd, F., Patel, V. B., & Preedy, V. R. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-405933-7.00003-2 · Cited by 7
Working Toward an Improved Understanding of Chronic Cardiorenal Syndrome Type 4.
Edmonston, D., Morris, J. D., & Middleton, J. (2018) · Advances in Chronic Kidney Disease · doi:10.1053/j.ackd.2018.08.010 · Cited by 8
Drp1 and Mitochondrial Autophagy Lend a Helping Hand in Adaptation to Pressure Overload
Miyamoto, S., & Brown, J. H. (2016) · Circulation · doi:10.1161/circulationaha.116.021796 · Cited by 7
Zhao, L., Han, L., Wei, X., Zhou, Y., Zhang, Y., Si, N., Wang, H., Yang, J. T., Bian, B., & Zhao, H. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.780016 · Cited by 6
James, A. S., Ugbaja, R. N., Ugwor, E. I., Thomas, F. C., Akamo, A. J., Akinloye, D. I., Eteng, O. E., Salami, S. K., Emmanuel, E. A., & Ugbaja, V. C. (2022) · Nutrition Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2022.11.026 · Cited by 6
IL-10 for cardiac autophagy modulation: New direction in the pursuit of perfection
Samanta, A., & Dawn, B. (2016) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2016.01.002 · Cited by 6
Activation of Gαq in Cardiomyocytes Increases Vps34 Activity and Stimulates Autophagy
Liu, S., Jiang, Y., Ballou, L. M., Zong, W., & Lin, R. Z. (2017) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000461 · Cited by 6
Circular RNAs: a small piece in the heart failure puzzle
Eshraghi, R., Shafie, D., Raisi, A., Goleij, P., & Mirzaei, H. (2024) · Functional & Integrative Genomics · doi:10.1007/s10142-024-01386-z · Cited by 6
Alammari, A. H., Isse, F. A., O’Croinin, C., Davies, N. M., & El‐Kadi, A. O. S. (2024) · Drug Metabolism and Disposition · doi:10.1124/dmd.124.001705 · Cited by 5
Effects of low dose of aliskiren on isoproterenol-induced acute myocardial infarction in rats
Bin‐Jaliah, I., Hussein, A. M., Sakr, H. F., & Eid, E. A. (2018) · Physiology International · doi:10.1556/2060.105.2018.2.11 · Cited by 5
Roles of autophagy in angiotensin II ‐induced cardiomyocyte apoptosis
Kobara, M., Toba, H., & Nakata, T. (2022) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.13719 · Cited by 5
Oxidative Stress and Mitochondrial Dysfunction in Cardiovascular Diseases
Hernndez-Resndiz, S., Buelna‐Chontal, M., Correa, F., & Zazuet, C. (2012) · InTech eBooks · doi:10.5772/35005 · Cited by 5
Molecular Signaling Mechanisms of the Renin-Angiotensin System in Heart Failure
Ferrario, C. M., Dell’Italia, L. J., & Varagić, J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-60987-6.00005-3 · Cited by 5
Cui, Y., Yang, Y., Tang, X., Wang, P., Cui, J., Chen, Y., & Zhang, T. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1555991 · Cited by 4
Sari, N. Y., Sia, C., Wong, R. C.-C., Lin, W., & Lim, Y. C. (2024) · European Heart Journal - Case Reports · doi:10.1093/ehjcr/ytae690 · Cited by 4
Ge, L., Ma, J.-J., Xu, J.-X., Wang, B., Adil, A., & Xu, H.-F. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.111650 · Cited by 4
Chambers, J. M., Croteau, D., Pimentel, D. R., Gower, A. C., Panagia, M., Baka, T., Qin, F., Luptak, I., & Colucci, W. S. (2025) · Journal of Molecular and Cellular Cardiology Plus · doi:10.1016/j.jmccpl.2025.100296 · Cited by 4
Yang, X., Fu, Y., Liu, J., Zhang, J., Liu, X., Peng, Y., Kyin, S. L., Zhang, M., & Zhou, D. (2023) · Nanomedicine · doi:10.2217/nnm-2022-0325 · Cited by 4
Müller, A., & Leichert, L. I. O. (2013) · Springer eBooks · doi:10.1007/978-94-007-5787-5_6 · Cited by 4
Sanz, R. L., Mazzei, L. J., Santino, N., Ingrasia, M., & Manucha, W. A. (2020) · Clínica e Investigación en Arteriosclerosis (English Edition) · doi:10.1016/j.artere.2020.02.003 · Cited by 4
Dai, D., Chiao, Y. A., Wessells, R. J., Bodmer, R., Szeto, H. H., & Rabinovitch, P. S. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-411596-5.00017-4 · Cited by 4
Self-citationPark, J., & Tallquist, M. D. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.99828-4 · Cited by 4
Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissuesPreprint
Pearson, G. L., Walker, E. M., Lawlor, N. T., Lietzke, A. C., Sidarala, V., Zhu, J., Stromer, T., Reck, E. C., Stendahl, A. M., Li, J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.08.02.502357 · Cited by 4
Transmembrane protein 117 knockdown protects against angiotensin-II-induced cardiac hypertrophy
Yang, Y., Wang, X., Yan, P., Wang, D., Luo, T., Zhou, Y., Chen, S., Liu, Q., Hou, J., & Wang, P. (2023) · Hypertension Research · doi:10.1038/s41440-023-01377-w · Cited by 4
Zhang, L., Xie, F., Zhang, F., & Lu, B. (2024) · Medicine · doi:10.1097/md.0000000000037994 · Cited by 3
SECONDARY MITOCHONDRIAL DYSFUNCTION
Khajuria, K., Khajuria, V., & Sawhney, V. (2021) · International Journal of Pharmacy and Pharmaceutical Sciences · doi:10.22159/ijpps.2021v13i3.40335 · Cited by 3
Fatty Acids and Cardiac Ischemia Reperfusion Injury
Batchu, S. N., Chaudhary, K. R., Zlobine, I., Pawa, J., & Seubert, J. M. (2016) · Elsevier eBooks · doi:10.1016/b978-1-63067-036-8.00003-2 · Cited by 3
Endonuclease G: The Link Between Mitochondria and Cardiac Hypertrophy?
Bugger, H., & Abel, E. D. (2012) · Circulation Research · doi:10.1161/res.0b013e318249dcc8 · Cited by 3
Ma, C., Ying, Y., Zhang, T., Zhang, W., Peng, H., Cheng, X., Xu, L., & TONG, H. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3105 · Cited by 3
Regulation of Mitochondrial Functions by Transcription Factor NRF2
Reddy, N. M., Qureshi, W., Potteti, H. R., Kalvakolanu, D. V., & Reddy, S. P. (2014) · Respiratory medicine · doi:10.1007/978-1-4939-0829-5_2 · Cited by 4
The role of captopril in leukotriene deficient type 1 diabetic mice
Guimarães, J. P. T., Queiroz, L. A. D., Menikdiwela, K. R., Pereira, N., Ramalho, T. R. D. O., Jancar, S., Moustaïd‐Moussa, N., & Martins, J. O. (2023) · Scientific Reports · doi:10.1038/s41598-023-49449-8 · Cited by 5
The Mitochondrial Calcium Uniporter of Pulmonary Type 2 Cells Determines Severity of ARDSPreprint
Islam, M. N., Gusarova, G. A., Das, S., Li, L., Monma, E., Murari, A., Owusu-Ansah, E., Bhattacharya, S., & Bhattacharya, J. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.18.427173 · Cited by 3
[Ancient Egyptian Odontology].
Berghult, B. (1999) · PubMed · Cited by 3
Targeting the non-neuronal cholinergic machinery: A novel approach to mitigate cardiac aging
Chakraborty, S., Tiwari, V., & Banerjee, S. K. (2025) · Ageing Research Reviews · doi:10.1016/j.arr.2025.102782 · Cited by 2
Chen, L., Zheng, L., Qin, Y. H., Liu, B., Zheng, Y., Tong, X., Dai, M., & Gong, G. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.10.053 · Cited by 2
Antioxidant Therapy in CVD: Hope or Hype
Nasser, S. A., & Dent, G. (2024) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-3-031-62131-4_6 · Cited by 2
Investigating the risk factors of cardiomyopathy in pregnant mothers
Norouzi, M., Amiri, Z., Ghavami, V., Madahali, M. H., Moradi, A., & Mosafarkhani, E. (2024) · International Journal of Cardiology · doi:10.1016/j.ijcard.2024.132696 · Cited by 2
Autophagy and Proteostasis in Cardiac Aging
Dai, D., & Rabinovitch, P. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-805253-2.00015-8 · Cited by 2
Self-citationChatterjee, S., Hossain, U., & Sil, P. C. (2019) · Springer eBooks · doi:10.1007/978-981-13-8946-7_19 · Cited by 2
Burtscher, M., & Gnaiger, E. (2013) · Springer eBooks · doi:10.1007/978-3-7091-1334-9_6 · Cited by 2
Kim, S.-W., Jang, W.-S., & Baek, K.-M. (2016) · 대한한의학회지 · doi:10.13048/jkm.16018 · Cited by 2
Cardiac Remodeling: The Course Toward Heart Failure – I. General Concepts
Cokkinos, D. V. (2019) · Springer eBooks · doi:10.1007/978-3-319-98186-4_12 · Cited by 2
Key Cellular Effectors in ROS-Mediated Cardiac Diseases
Chaudhuri, R. D., Rana, S., Datta, K., & Sarkar, S. (2019) · Springer eBooks · doi:10.1007/978-981-13-8946-7_7 · Cited by 2
Roles of Macrophage Mitochondrial Oxidative Stress and Mitochondrial Fission in Atherosclerosis
Wang, Y. (2014) · doi:10.7916/d84x55xn · Cited by 2
Cardiovascular disease in aging and the role of oxidative stress
Orliaguet, L., Patel, V. B., Preedy, V. R., & Alzaïd, F. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818698-5.00003-1 · Cited by 2
Free Radicals and Biomarkers Related to the Diagnosis of Cardiorenal Syndrome
Restini, C. B. A., Pereira, B. F. M., & Geleilete, T. J. M. (2016) · InTech eBooks · doi:10.5772/63898 · Cited by 2
Angiotensin II and skeletal muscle abnormalities
Kinugawa, S. (2017) · Experimental Physiology · doi:10.1113/ep086216 · Cited by 2
Oxidative Stress in Cardiac Remodeling Post-Ischemia/Reperfusion: Friend or Foe?
Abidi, E., Kaplan, A., Booz, G. W., & Zouein, F. A. (2019) · Springer eBooks · doi:10.1007/978-981-13-8273-4_12 · Cited by 2
TEAD1 is a novel regulator of NRF2 and oxidative stress response in cardiomyocytesPreprint
Jagannathan, R., Lee, J., DeVallance, E., Negi, V., Mandi, V., Vyas, H., Li, F., Pagano, P. J., Yechoor, V. K., & Moulik, M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.04.06.647438 · Cited by 2
Gαq Signaling in the Regulation of Autophagy and Heart Failure
Kolpakov, M. A., Tilley, D. G., & Sabri, A. (2017) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000471 · Cited by 1
Therapeutic Strategies for Combating Reactive Oxygen Species in Cardiovascular Diseases
Mansour, H. M. (2024) · Oxidative stress in applied basic research and clinical practice · doi:10.1007/978-3-031-62131-4_2 · Cited by 1
Pencheva, M. M., Manchorova-Veleva, N. А., Baruh, D., Rusinov, G., & Vangelov, L. (2025) · Life · doi:10.3390/life15020324 · Cited by 1
A multiscale mechanobiological model of physiological and pathological cardiac hypertrophy
Xu, S., Chen, X., Peng, X., Li, B., & Feng, X. (2025) · Journal of the Mechanics and Physics of Solids · doi:10.1016/j.jmps.2025.106349 · Cited by 1
Circulating Biomarkers in the Detection of Cardiovascular Toxicity
Stankovic, S. D., Radisavljevic, N. M., Bajić, Z., Polovina, M. M., & Djuric, D. M. (2025) · Advances in biochemistry in health and disease · doi:10.1007/978-3-031-90598-8_32 · Cited by 2
Cardiometabolic adaptations in the cave nectar bat Eonycteris spelaea
Yu, F., Gamage, A. M., Ja, K. P. M. M., Foo, R., Lin, Y., Wang, L., Pua, C. J., Chan, W. O. Y., Crespo-Avilan, G. E., Pena, E. M., et al. (2026) · Communications Biology · doi:10.1038/s42003-026-09792-8 · Cited by 1
Gao, X., Pan, Y., Liu, Q., & Wu, H. (2026) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2026.1748411 · Cited by 1
Yang, X., Cheng, K., Chen, C., Zhang, Y., & Wang, D. W. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27177734 · Cited by 1
Mitochondrial Damage and Mitophagy in Ischemia/Reperfusion-Induced Liver Injury
Go, K. L., Lee, S., Behrns, K. E., & Js, K. (2017) · Springer eBooks · doi:10.1007/978-3-319-58106-4_9 · Cited by 1
Redox distress in organ fibrosis: The role of noncoding RNAs
Miguel, V., & Lamas, S. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-818606-0.00037-7 · Cited by 1
Circulation Research Most Read: 2010–2011
Editors, T. (2012) · Circulation Research · doi:10.1161/circresaha.112.281089 · Cited by 1
(Myocardium Remodelling: From Adaptation Mechanisms to Heart Failure Development)
Laška, M., Novàkovâ, M., & Stračina, T. (2024) · Cor et Vasa · doi:10.33678/cor.2023.090 · Cited by 1
Đurašević, S., Zdravkovic, M. D., Nikolić, V., & Todorović, Z. (2024) · Advances in biochemistry in health and disease · doi:10.1007/978-3-031-62806-1_21 · Cited by 1
Autophagy fine-tuning by angiotensin-(1-9) in cultured rat cardiomyocytes
Bustamante, M., Quiroga, C., Mancilla, G., Gómez, W., Tapia, A., Figueroa, R., Mondaca‐Ruff, D., Oyarzún, I., Verdejo, H., Lavandero, S., et al. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1408325 · Cited by 2
SBK3 suppresses angiotensin II-induced cardiac hypertrophy by regulating mitochondrial metabolism
Yang, A., Cao, J., Gu, J., Zhu, X., Qian, Y., Qian, H., Zhao, W., Wang, Y., & Zhu, W.-Z. (2025) · Scientific Reports · doi:10.1038/s41598-025-05584-y · Cited by 1
Oxidative Stress and Nitrosative Stress
Schulz, R., & Lisa, F. D. (2016) · Springer eBooks · doi:10.1007/978-3-319-31251-4_10 · Cited by 1
Mitochondrial Dysfunction and Oxidative Stress: Focusing on Cardiac Hypertrophy and Heart Failure
Katare, P. B., Nizami, H. L., & Banerjee, S. K. (2019) · Springer eBooks · doi:10.1007/978-981-13-8273-4_25 · Cited by 1
Cardiomyocytes in Heart Failure
Kartha, C. C. (2021) · Springer eBooks · doi:10.1007/978-3-030-85536-9_15 · Cited by 1
Oxidative Stress in Heart Failure
Sverdlov, A. L., Ngo, D. T. M., & Colucci, W. S. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-60987-6.00008-9 · Cited by 1
Is the Therapeutic Window for Mitochondrial ROS Half-Open or Half-Closed?
Carley, A. N., & Lewandowski, E. D. (2014) · Circulation Research · doi:10.1161/circresaha.114.304492 · Cited by 1
The Ten Most Read Articles Published in Circulation Research in 2011
Bolli, R., & Editors, F. T. (2012) · Circulation Research · doi:10.1161/res.0b013e31824c38b7 · Cited by 1
Paunas, T. I. (2011) · NORA - Norwegian Open Research Archives · Cited by 1
Curtis, J. (2011) · University of Minnesota Digital Conservancy (University of Minnesota)
Metabolic Remodeling in the Development of Heart Failure
Nguyễn, T. D. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-802394-5.00012-1
Proteome Turnover in Mouse Aging: In Vivo Studies by Stable Isotope Mass Spectrometry
Basisty, N. (2015) · ResearchWorks at the University of Washington (University of Washington)
Zelluläre Mechanismen der systolischen Herzinsuffizienz
Maack, C. (2017) · Der Klinikarzt · doi:10.1055/s-0043-120228
Tallquist, M. D. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99828-3
Ni, R. (2018) · Scholarship@Western (Western University)
Coulis, G., Shi, Y., Labbé, D. P., Bergeron, A., Sahmi, F., Vinette, V., Karsenty, G., Allen, B. G., Tremblay, M. L., Tardif, J., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/763953
Maiolino, G., Ravarotto, V., & Calò, L. A. (2019) · Springer eBooks · doi:10.1007/978-981-13-8273-4_26
Restore mitophagy is essential to prevent cardiac oxidative stress during hypertrophyPreprint
Peugnet, V., Chwastyniak, M., Lancel, S., Bultot, L., Fourny, N., Beseme, O., Loyens, A., Heyse, W., Amouyel, P., Bertrand, L., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.12.426366
ZhouWen, F., Xue, Z., & Xie, Z.-L. G.-L. (2012)
Mallick, U. (2022) · Springer eBooks · doi:10.1007/978-3-030-90065-6_12
Metadata
- Authors
- Dai, D.-F., Johnson, S. C., Villarin, J. J., Chin, M. T., Nieves-Cintrón, M., Chen, T., Marcinek, D. J., Dorn, G. W., Kang, Y. J., Prolla, T. A., Santana, L. F., & Rabinovitch, P. S.
- Affiliations
- University of Louisville (US)
- From the Departments of Pathology (D.-F.D., S.C.J., T.C., P.S.R.), Radiology (J.J.V., D.J.M.), Cardiovascular Medicine (M.T.C.), Physiology and Biophysics (M.N.-C., L.F.S.), University of Washington, Seattle; Department of Internal Medicine (G.W.D.), Washington University School of Medicine, St Louis, MO; Departments of Medicine and Pharmacology and Toxicology (Y.J.K.), University of Louisville School of Medicine, KY; and Department of Genetics and Medical Genetics (T.A.P.), University of...
- ORCID
- Venue
- Circulation Research
- Published
- 2011-04
- Volume
- 108
- Issue
- 7
- Pages
- 837-846
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- PMC
- PMC3785241
- OpenAlex
- W2117205119
- Cited by
- 527
- References
- 35
- Citations by year
- 2026: 14 · 2025: 35 · 2024: 30 · 2023: 32 · 2022: 28 · 2021: 42 · 2020: 46 · 2019: 34 · 2018: 31 · 2017: 29 · 2016: 44 · 2015: 34 · 2014: 37 · 2013: 36 · 2012: 41
- FWCI
- 16.21
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (AG001751, AG013280)
- National Institute on Aging (AG-028455, AG001751, P01AG001751, AG013280, AG035844, RC1AG035844, R01AG028455, P30AG013280)
- National Heart, Lung, and Blood Institute (R01HL101186, HL-101186, R01HL063760, HL063760, R01HL059888)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Mitochondrial Function and Pathology
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Keywords
- mitochondrial oxidative stress, reactive oxygen species, angiotensin II, cardiac hypertrophy, heart failure, catalase, mitochondrial DNA damage, mitochondrial DNA deletions, autophagy, mitochondrial biogenesis, hypertensive cardiomyopathy, myocardial fibrosis, zidovudine, mitochondria-targeted antioxidants
- MeSH terms
- Angiotensin II, Animals, Catalase, DNA Damage, DNA, Mitochondrial, Gene Expression Regulation, Cardiomegaly, Heart Failure, Mice, Transgenic, Mitochondria, Heart, Zidovudine, Reactive Oxygen Species, Oxidative Stress, Reverse Transcriptase Inhibitors, Models, Animal, Myocytes, Cardiac, GTP-Binding Protein alpha Subunits, Gq-G11, Mice
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
