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Cited by 648

The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.

Treatment of Obesity: Weight Loss and Bariatric Surgery

Open access
Wolfe, Bruce M., Kvach, Elizaveta, Eckel, Robert H.·2016·Circulation Research

Abstract

This review focuses on the mechanisms underlying, and indications for, bariatric surgery in the reduction of cardiovascular disease (CVD), as well as other expected benefits of this intervention. The fundamental basis for bariatric surgery for the purpose of accomplishing weight loss is the determination that severe obesity is a disease associated with multiple adverse effects on health, which can be reversed or improved by successful weight loss in patients who have been unable to sustain weight loss by nonsurgical means. An explanation of possible indications for weight loss surgery as well as specific bariatric surgical procedures is presented, along with review of the safety literature of such procedures. Procedures that are less invasive or those that involve less gastrointestinal rearrangement accomplish considerably less weight loss but have substantially lower perioperative and longer-term risk. The ultimate benefit of weight reduction relates to the reduction of the comorbidities, quality of life, and all-cause mortality. With weight loss being the underlying justification for bariatric surgery in ameliorating CVD risk, current evidence-based research is discussed concerning body fat distribution, dyslipidemia, hypertension, diabetes mellitus, inflammation, obstructive sleep apnea, and others. The rationale for bariatric surgery reducing CVD events is discussed and juxtaposed with impacts on all-cause mortalities. Given the improvement of established obesity-related CVD risk factors after weight loss, it is reasonable to expect a reduction of CVD events and related mortality after weight loss in populations with obesity. The quality of the current evidence is reviewed, and future research opportunities and summaries are stated.

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Crossref · 10.1161/circresaha.116.307591

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Metadata

Authors
Wolfe, B. M., Kvach, E., & Eckel, R. H.
Venue
Circulation Research
Published
2016-05-27
Volume
118
Issue
11
Pages
1844-1855
ISSN
  • 0009-7330 (ISSN-L)
  • 1524-4571
OpenAlex
W2400321486
Cited by
648
References
117
FWCI
15.60
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Treatment of Obesity: Weight Loss and Bariatric Surgery. https://app.cochat.ai/papers/10.1161/circresaha.116.307591
The paper
Wolfe, B. M., Kvach, E., & Eckel, R. H. (2016). Treatment of Obesity: Weight Loss and Bariatric Surgery. Circulation Research. https://doi.org/10.1161/circresaha.116.307591

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.