The DOI matches its Crossref record; 378 of the 379 references it cites were found in a registry or an index.
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
Open accessAbstract
Reactive oxygen species (ROS) are well known for their role in mediating both physiological and pathophysiological signal transduction. Enzymes and subcellular compartments that typically produce ROS are associated with metabolic regulation, and diseases associated with metabolic dysfunction may be influenced by changes in redox balance. In this review, we summarize the current literature surrounding ROS and their role in metabolic and inflammatory regulation, focusing on ROS signal transduction and its relationship to disease progression. In particular, we examine ROS production in compartments such as the cytoplasm, mitochondria, peroxisome, and endoplasmic reticulum and discuss how ROS influence metabolic processes such as proteasome function, autophagy, and general inflammatory signaling. We also summarize and highlight the role of ROS in the regulation metabolic/inflammatory diseases including atherosclerosis, diabetes mellitus, and stroke. In order to develop therapies that target oxidative signaling, it is vital to understand the balance ROS signaling plays in both physiology and pathophysiology, and how manipulation of this balance and the identity of the ROS may influence cellular and tissue homeostasis. An increased understanding of specific sources of ROS production and an appreciation for how ROS influence cellular metabolism may help guide us in the effort to treat cardiovascular diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“ROS act as one of the key molecules that regulate inflammatory signaling [52].”
From A tailored bioactive 3D porous poly(lactic-acid)-exosome scaffold with osteo-immunomodulatory and osteogenic differentiation properties (2022) · cites this paper as [52]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
4 retracted
Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
Zhang, H., Bosch-Marce, M., Shimoda, L. A., Tan, Y. S., Baek, J. H., Wesley, J. B., Gonzalez, F. J., & Semenza, G. L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m800102200 · Cited by 1,601
RetractedMartinez, J., Malireddi, R. K. S., Lu, Q., Cunha, L. D., Pelletier, S., Gingras, S., Orchard, R., Guan, J.-L., Tan, H., Peng, J., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3192 · Cited by 758
RetractedXu, J., Wu, Y., Song, P., Zhang, M., Wang, S., & Zou, M. (2007) · Circulation · doi:10.1161/circulationaha.106.684795 · Cited by 193
RetractedZou, M., Hou, X., Shi, C., Kirkpatick, S., Liu, F., Goldman, M. H., & Cohen, R. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300215200 · Cited by 168
RetractedRepertoires of Autophagy in the Pathogenesis of Ocular Diseases
Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351
How mitochondria produce reactive oxygen species
Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207
Autophagy in the Pathogenesis of Disease
Levine, B., & Kroemer, G. (2008) · Cell · doi:10.1016/j.cell.2007.12.018 · Cited by 7,069
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
Bedard, K., & Krause, K.-H. (2007) · Physiological Reviews · doi:10.1152/physrev.00044.2005 · Cited by 6,989
Ayala, A., Muñoz, M., & Argüelles, S. (2014) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2014/360438 · Cited by 6,837
Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760
Research works printed but not linked: 2
- 10.1172/JCI19451 · DOI · Paper page
- 10.1172/JCI11927 · DOI · Paper page
Cited by
Sorted by citations
Items 501–600 of 1,000
Gupta, V. K., Kumar, A., Pereira, M. D. L., Siddiqi, N. J., & Sharma, B. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17145177 · Cited by 36
Mazouz, W., Haouli, N. E. H., Gali, L., Vezza, T., Bensouıcı, C., Mebrek, S., Hamel, T., Gálvez, J., & Djeddi, S. (2020) · South African Journal of Botany · doi:10.1016/j.sajb.2020.08.021 · Cited by 35
Morgulchik, N., & Kamaly, N. (2021) · ACS Applied Nano Materials · doi:10.1021/acsanm.1c00170 · Cited by 35
Redox regulation of DUBs and its therapeutic implications in cancer
Tyagi, A., Haq, S., & Ramakrishna, S. (2021) · Redox Biology · doi:10.1016/j.redox.2021.102194 · Cited by 35
The Intestinal Redox System and Its Significance in Chemotherapy‐Induced Intestinal Mucositis
Yu, Q., Zhang, H., Guo, Y., Han, B., & Jiang, P. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/7255497 · Cited by 36
Therapeutic strategies for liver diseases based on redox control systems
Lee, J., Kim, J., Lee, R., Lee, E., Choi, T. G., Lee, A. S., Yoon, Y., Park, G., Namgoong, J., Lee, S., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113764 · Cited by 37
Beltrán-Sarmiento, E., Arregoitia-Sarabia, C. K., Floriano-Sánchez, E., Sandoval‐Pacheco, R., Galván-Hernández, D. E., Coballase-Urrutía, E., Carmona‐Aparicio, L., Ramos-Reyna, E., Rodríguez‐Silverio, J., & Cárdenas‐Rodríguez, N. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/7954371 · Cited by 35
Succinylation modification: a potential therapeutic target in stroke
Lian, J., Liu, W., Hu, Q., & Zhang, X. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.382229 · Cited by 36
Ultrasmall Cu2O@His Nanozymes with RONS Scavenging Capability for Anti-inflammatory Therapy
Li, S., Chen, Z., Wang, M., Yang, F., Zhang, S., Qiao, C., Chu, W., & Yue, W. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c15083 · Cited by 34
A Systematic Review of Proteomics in Obesity: Unpacking the Molecular Puzzle
Rodríguez-Muñoz, A., Rad, H. M., Martín-Chaves, L., Benítez‐Porres, J., Rodríguez‐Capitán, J., Gonzalez-Jimenez, A., Insenser, M. R., Tinahones, F. J., & Murri, M. (2024) · Current Obesity Reports · doi:10.1007/s13679-024-00561-4 · Cited by 34
Engineering extracellular vesicles for ROS scavenging and tissue regeneration
Dayem, A. A., Yan, E., Do, M., Kim, Y., Lee, Y. K., Cho, S., & Kim, D. (2024) · Nano Convergence · doi:10.1186/s40580-024-00430-9 · Cited by 34
Xie, J., Yuan, C., Yang, S., Ma, Z., Li, W., Mao, L., Jiao, P., & Liu, W. (2024) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-024-00659-6 · Cited by 41
Reductive stress: The key pathway in metabolic disorders induced by overnutrition
Zhang, S., Wang, N., Gao, Z., Gao, Z., Wang, X., Xie, H., Wang, C.-Y., & Zhang, S. (2025) · Journal of Advanced Research · doi:10.1016/j.jare.2025.01.012 · Cited by 40
Gao, B., Huang, X., Fu, J., Chen, L., Deng, Z., Wang, S.-H., Zhu, Y., Xu, C., Zhang, Y., Zhang, M., et al. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03346-6 · Cited by 35
Yeh, C.-C., Wu, J.-Y., Lee, G.-L., Wen, H.-T., Lin, P., & Kuo, C.-C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20246115 · Cited by 34
The roles of microRNA in redox metabolism and exercise-mediated adaptation
Torma, F., Gombos, Z., Jókai, M., Berkes, I., Takeda, M., Mimura, T., Radak, Z. O., & Győri, F. J. (2020) · Journal of sport and health science/Journal of Sport and Health Science · doi:10.1016/j.jshs.2020.03.004 · Cited by 37
Diniz, D. P., Lorencini, D. A., Berretta, A. A., Cintra, M., Lia, É. N., Jordão, A. A., & Coelho, E. B. (2020) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2020/7538232 · Cited by 34
The Role Played by Mitochondria in FcεRI-Dependent Mast Cell Activation
Chelombitko, M. A., Chernyak, B. V., Fedorov, A. V., Zinovkin, R. A., Razin, E., & Paruchuru, L. B. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.584210 · Cited by 35
Song, Y., Xing, H., He, Y., Zhang, Z., Shi, G., Su, W., Liu, Y., Harrington, E. O., Sellke, F. W., & Feng, J. (2021) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2021.06.029 · Cited by 34
Innate Immunity: A Balance between Disease and Adaption to Stress
Faenza, I., & Blalock, W. L. (2022) · Biomolecules · doi:10.3390/biom12050737 · Cited by 34
The role of immune-mediated alterations and disorders in ALS disease
Rodrigues Lima-Junior, J., Sulzer, D., Lindestam Arlehamn, C. S., & Sette, A. (2021) · Human Immunology · doi:10.1016/j.humimm.2021.01.017 · Cited by 33
Inhibition of NADPH Oxidases Prevents the Development of Osteoarthritis
Han, J., Park, D., Park, J. Y., & Han, S. W. (2022) · Antioxidants · doi:10.3390/antiox11122346 · Cited by 33
Role of Perilipins in Oxidative Stress—Implications for Cardiovascular Disease
Cinato, M., Andersson, L. K., Miljanovic, A., Laudette, M., Kunduzova, O., Borén, J., & Levin, M. C. (2024) · Antioxidants · doi:10.3390/antiox13020209 · Cited by 33
Role of reactive oxygen species in myelodysplastic syndromes
Jing, Q., Zhou, C., Zhang, J., Zhang, P., Wu, Y., Zhou, J., Tong, X., Li, Y., Du, J., & Wang, Y. (2024) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-024-00570-0 · Cited by 33
The Role of Nrf2 in the Regulation of Mitochondrial Function and Ferroptosis in Pancreatic Cancer
Baiskhanova, D. M., & Schäfer, H. (2024) · Antioxidants · doi:10.3390/antiox13060696 · Cited by 35
The role of oxidative stress in aortic dissection: a potential therapeutic target
Xu, S., Han, X., Wang, X., Yu, Y., Qu, C., Liu, X., & Yang, B. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1410477 · Cited by 36
Dynamics of intracellular and intercellular redox communication
Sies, H. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.11.002 · Cited by 35
Wei, X., Manandhar, L., Kim, H., Chhetri, A., Hwang, J., Jang, G., Park, C., & Park, R. (2025) · Antioxidants · doi:10.3390/antiox14020126 · Cited by 39
Zeng, Q., Du, S., Yuan, R., Zeng, Y., Li, X., Wu, Y., Chen, K., Tao, L., Tang, Z., & Deng, X. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202500734 · Cited by 34
Endothelial Dysfunction in Cardiovascular Diseases
Biswas, I., & Khan, G. A. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.89365 · Cited by 33
Aziz, I. A., Malferrari, M., Roggiani, F., Tullii, G., Rapino, S., & Antognazza, M. R. (2020) · iScience · doi:10.1016/j.isci.2020.101091 · Cited by 33
Feidantsis, K. G., Georgoulis, I., Zachariou, A., Campaz, B., Christoforou, M., Pörtner, H., & Michaelidis, B. (2020) · Journal of Comparative Physiology B · doi:10.1007/s00360-020-01278-1 · Cited by 33
Kopiasz, Ł., Dziendzikowska, K., Gajewska, M., Wilczak, J., Harasym, J., Żyła, E., Kamola, D., Oczkowski, M., Królikowski, T., & Gromadzka-Ostrowska, J. (2020) · Antioxidants · doi:10.3390/antiox9050375 · Cited by 33
Gonzalez‐Rivera, J. C., Baldridge, K. C., Wang, D., Patel, K., Chuvalo-Abraham, J. C. L., Ruiz, L. H., & Contreras, L. M. (2020) · Communications Biology · doi:10.1038/s42003-020-01118-6 · Cited by 35
Signaling Integration of Hydrogen Sulfide and Iron on Cellular Functions
Arif, H. M., Qian, Z., & Wang, R. (2021) · Antioxidants and Redox Signaling · doi:10.1089/ars.2021.0203 · Cited by 33
Chu, X., Li, L., Yan, W., & Ma, H. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/5180242 · Cited by 33
Arterial stiffness and atrial fibrillation: A review
Lage, J. G. B., Bortolotto, A. L., Scanavacca, M., Bortolotto, L. A., & Darrieux, F. (2022) · Clinics · doi:10.1016/j.clinsp.2022.100014 · Cited by 33
Hambardikar, V. D., Guitart‐Mampel, M., Scoma, E. R., Urquiza, P., Gowda, G. A. N., Raftery, D., Collins, J. A., & Solesio, M. E. (2022) · Antioxidants · doi:10.3390/antiox11040685 · Cited by 33
Good bacteria, oxidative stress and neurological disorders: Possible therapeutical considerations
Soheili, M., Alinaghipour, A., & Salami, M. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120605 · Cited by 33
Sun, L., Zhang, Y., Wen, S., Li, Q., Chen, R., Lai, X., Zhang, Z., Zhou, Z., Xie, Y., Zheng, X., et al. (2022) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2022.113255 · Cited by 33
Molecular mechanisms of endothelial dysfunction in coronary microcirculation dysfunction
Zhang, Z., Li, X., He, J., Wang, S., Wang, J., Liu, J., & Wang, Y. (2023) · Journal of Thrombosis and Thrombolysis · doi:10.1007/s11239-023-02862-2 · Cited by 33
Novel Anti-Inflammatory Therapies in Coronary Artery Disease and Acute Coronary Syndromes
Dimitroglou, Y., Aggeli, C., Theofilis, P., Tsioufis, P., Oikonomou, E. K., Chasikidis, C., Tsioufis, K. P., & Tousoulis, D. (2023) · Life · doi:10.3390/life13081669 · Cited by 35
Yoon, D.-S., Lee, Y., Park, J. C., Lee, M., & Lee, J. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.123739 · Cited by 33
Villegas-Fuentes, A., la Torre, A. R.-D., Vilchis-Nestor, A. R., & Luque, P. A. (2023) · Chemosphere · doi:10.1016/j.chemosphere.2023.139577 · Cited by 32
Xu, L., An, T., Jia, B., Wu, Q., Shen, J., Jin, J., Liu, J., & Li, C. (2023) · Burns & Trauma · doi:10.1093/burnst/tkad062 · Cited by 32
Oocytes maintain low ROS levels to support the dormancy of primordial follicles
Qin, S., Chi, X., Zhu, Z., Chen, C., Zhang, T., He, M., Gao, M., Zhao, T., Zhang, J., Zhang, L., et al. (2024) · Aging Cell · doi:10.1111/acel.14338 · Cited by 32
Mitochondrial bioenergetics dysfunction in T2DM: linking oxidative stress to insulin resistance
Feng, Z., Tan, Z., & Lu, D. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1674477 · Cited by 32
Zádor, F., Nagy-Grócz, G., Kékesi, G., Dvorácskó, S., Szűcs, E., Tömböly, C., Horváth, G., Benyhe, S., & Vécsei, L. (2019) · Molecules · doi:10.3390/molecules24203709 · Cited by 33
Beisl, J., Pahlke, G., Abeln, H., Ehling‐Schulz, M., Favero, G. D., Varga, E., Warth, B., Sulyok, M., Abia, W. A., Ezekiel, C. N., et al. (2020) · Archives of Toxicology · doi:10.1007/s00204-020-02658-w · Cited by 32
Resuscitating the Globally Ischemic Brain: TTM and Beyond
Hosseini, M., Wilson, R. H., Crouzet, C., Amirhekmat, A., Wei, K. S., & Akbari, Y. (2020) · Neurotherapeutics · doi:10.1007/s13311-020-00856-z · Cited by 33
Effects of REDOX in Regulating and Treatment of Metabolic and Inflammatory Cardiovascular Diseases
Wang, K., Dong, Y., Liu, J., Qian, L., Wang, T., Gao, X., Wang, K., & Zhou, L. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/5860356 · Cited by 34
Chotphruethipong, L., Sukketsiri, W., Battino, M. A., & Benjakul, S. (2021) · RSC Advances · doi:10.1039/d0ra07135h · Cited by 32
The Role of Micronutrients to Support Immunity for COVID-19 Prevention
Ahmed, M. H., Hassan, A., & Molnár, J. (2021) · Revista Brasileira de Farmacognosia · doi:10.1007/s43450-021-00179-w · Cited by 33
Wu, Y., Cowin, G., Moonshi, S. S., Nguyen, D. H. T., Fithri, N. A., Whittaker, A. K., Zhang, R., & Ta, H. T. (2021) · Materials Science and Engineering C · doi:10.1016/j.msec.2021.112477 · Cited by 32
Chi, Z., Lin, H., Wang, X., Meng, X., Zhou, J., Xiang, L., Cao, G., Wu, P., Cai, Z., & Zhao, X. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.156047 · Cited by 32
Neurobiological mechanisms of mood disorders: Stress vulnerability and resilience
Pereira, C. M., Castro, F. C. D. A. Q., Barcelos, R. M., Chiepe, K. C. M. B., Rossoni, J. V., Ambrósio, R. P., Chiarelli-Neto, O., & Pesarico, A. P. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.1006836 · Cited by 36
Growth Hormone–Releasing Hormone in Endothelial Inflammation
Barabutis, N., Akhter, M. S., Kubra, K., & Jackson, K. E. (2022) · Endocrinology · doi:10.1210/endocr/bqac209 · Cited by 32
Bahrami, R., Pourhajibagher, M., Parker, S. P. A., Esmaeili, D., & Bahador, A. (2023) · Photodiagnosis and Photodynamic Therapy · doi:10.1016/j.pdpdt.2023.103288 · Cited by 32
Bimetallic Metal–Organic Framework for Mitigating Aseptic Osteolysis
Pan, H., Miao, X., Deng, J., Pan, C., Cheng, X., & Wang, X. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c19449 · Cited by 32
Oxidative Stress in Muscle Diseases: Current and Future Therapy
Serra, A. J., Prokić, M. D., Vasconsuelo, A., & Pinto, J. R. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/6439138 · Cited by 32
Yang, Y., Wang, Y., Wei, S., Wang, X., & Zhang, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242115889 · Cited by 32
Controlling pyroptosis through post-translational modifications of gasdermin D
Zhang, N., & Xu, D. (2025) · Developmental Cell · doi:10.1016/j.devcel.2025.02.005 · Cited by 33
Yuan, Z., Li, Y., Sun, M., Yuan, M., Han, Z., Li, X., Liu, S., Sun, Y., Cao, J., & Fan, L. (2025) · Theranostics · doi:10.7150/thno.106991 · Cited by 33
Zhou, J., Zhang, L., Zheng, B., Zhang, L., Qin, Y., Zhang, X., Yang, Z., Nie, Z.-Y., Yang, G., Yu, J. Q., et al. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.113208 · Cited by 31
de Morais, A. L. F., Rijo, P. M., Batanero, B., & Nicolai, M. (2020) · Biosensors · doi:10.3390/bios10090121 · Cited by 32
Toxicogenicity and mechanistic pathways of aflatoxin B1 induced renal injury
Dlamini, N. Z., Somboro, A. M., Amoako, D. G., Arhin, I., Khumalo, H. M., & Khan, R. B. (2021) · Environmental Toxicology · doi:10.1002/tox.23306 · Cited by 31
The effect of lactoferrin in aging: role and potential
Li, B., Zhang, B., Liu, X., Zheng, Y., Han, K., Liu, H., Wu, C., Li, J., Fan, S., Peng, W., et al. (2021) · Food & Function · doi:10.1039/d1fo02750f · Cited by 32
Thyroid hormone-dependent regulation of metabolism and heart regeneration
Ross, I., Omengan, D. B., Huang, G. N., & Payumo, A. Y. (2021) · Journal of Endocrinology · doi:10.1530/joe-21-0335 · Cited by 32
Rashtbari, S., Dehghan, G., Amini, M., Khorram, S., & Khataee, A. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.133747 · Cited by 31
Villarreal‐García, V., Estupiñan‐Jiménez, J. R., Vivas‐Mejía, P. E., González-Villasana, V., Vázquez-Guillén, J. M., & Reséndez‐Pérez, D. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.980694 · Cited by 32
Yan, L., Guo, X., Zhou, J., Zhu, Y., Zhang, Z., & Chen, H. (2022) · Antioxidants · doi:10.3390/antiox12010059 · Cited by 32
Caballero-García, A., Noriega, D. C., Roche, E., Drobnic, F., & Córdova, A. (2023) · Nutrients · doi:10.3390/nu15112587 · Cited by 34
Tan, Y., Nie, W., Chen, C., He, X., Xu, Y., Ma, X., Zhang, J., Tan, M., Rong, P., & Wang, W. (2019) · Experimental Biology and Medicine · doi:10.1177/1535370219844472 · Cited by 31
Wu, H., Huang, S., Zhu, Y., Li, J., Pang, X., Tang, Y., Li, S., Ji, P., Ding, S., Cheng, W., et al. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202212669 · Cited by 30
Apweiler, M., Saliba, S. W., Sun, L., Streyczek, J., Normann, C., Hellwig, S., Bräse, S., & Fiebich, B. L. (2024) · Molecular Psychiatry · doi:10.1038/s41380-024-02614-5 · Cited by 31
Danhong Injection Alleviates Postoperative Intra-abdominal Adhesion in a Rat Model
Wu, Y., Wei, G., Yu, J., Chen, Z., Xu, Z., Shen, R., Liang, T., Zheng, L., Wang, K., Sun, X., et al. (2019) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2019/4591384 · Cited by 30
Yusuf, A., & Casey, A. (2019) · Toxicology in Vitro · doi:10.1016/j.tiv.2019.104641 · Cited by 30
Antognelli, C., Perrelli, A., Armeni, T., Talesa, V. N., & Retta, S. F. (2020) · Antioxidants · doi:10.3390/antiox9020124 · Cited by 30
Antioxidant and Anti-Inflammatory Effects of NCW Peptide from Clam Worm ( Marphysa sanguinea )
Park, Y. R., Park, C., & Soh, Y. (2020) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2003.03050 · Cited by 31
Khedr, S. I., Mokhamer, E.-H. M., Hassan, A. A., El-Feki, A. S., El‐Khodary, G. M., & El-Gerbed, M. S. A. (2020) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2020.10.026 · Cited by 30
Yuan, G., Shi, S., Jia, Q., Shi, J., Shi, S., Zhang, X., Shou, X., Zhu, X., & Hu, Y. (2021) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2021/6633402 · Cited by 30
Tackling Ischemic Reperfusion Injury With the Aid of Stem Cells and Tissue Engineering
Zamorano, M., Castillo, R. L., Beltrán, J. F., Herrera, L., Farias, J. A., Antileo, C., Aguilar-Gallardo, C., Pessoa, A., Calle, Y., & Farías, J. G. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.705256 · Cited by 30
Halophilic Carotenoids and Breast Cancer: From Salt Marshes to Biomedicine
Giani, M., Montoyo-Pujol, Y. G., Peiró, G., & Martínez‐Espinosa, R. M. (2021) · Marine Drugs · doi:10.3390/md19110594 · Cited by 31
Metallofullerenols in biomedical applications
Grębowski, J., & Litwinienko, G. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114481 · Cited by 30
Liu, F., Chen, J., Hu, W., Gao, C., Zeng, Z., Cheng, S., Yu, K., Qian, Y. H., Xu, D., Zhu, G., et al. (2022) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.03.002 · Cited by 31
Chen, X.-F., Lin, Z., Qi, Z., Cai, Z., & Chen, Z. (2022) · Environmental Chemistry Letters · doi:10.1007/s10311-022-01531-9 · Cited by 30
Iannuzzo, F., Piccolo, V., Novellino, E., Schiano, E., Salviati, E., Summa, V., Campiglia, P., Tenore, G. C., & Maisto, M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113557 · Cited by 30
Wang, Y., Dai, X., Wu, L., Xiang, H., Chen, Y., & Zhang, R. (2023) · Biomaterials · doi:10.1016/j.biomaterials.2023.122178 · Cited by 30
Sitagliptin inhibits vascular inflammation via the SIRT6-dependent signaling pathway
He, Y., Yang, G., Yao, F., Xian, Y., Wang, G., Chen, L., Lv, X., Gao, H., Zheng, Z., Sun, L., et al. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.105805 · Cited by 30
Kocken, J. M. M., & Martins, P. A. D. C. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21238901 · Cited by 30
Liu, H., Wang, X., Gao, H., Yang, C., & Xie, C. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1191426 · Cited by 29
Nanozymes With Osteochondral Regenerative Effects: An Overview of Mechanisms and Recent Applications
Sun, X., Xu, X., Yue, X., Wang, T., Wang, Z., Zhang, C., & Wang, J. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301924 · Cited by 29
Aging and “Age-Related” Diseases - What Is the Relation?
Kopp, W. (2024) · Aging and Disease · doi:10.14336/ad.2024.0570 · Cited by 31
Recent advances of lipid droplet-targeted AIE-active materials for imaging, diagnosis and therapy
Yuan, S., & Zhao, E. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116802 · Cited by 29
Graphene nanocomposites for transdermal biosensing
Tabish, T. A., Abbas, A., & Narayan, R. J. (2021) · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1699 · Cited by 29
Ali, I., Yang, M., Wang, Y., Yang, C., Shafiq, M., Wang, G., & Li, L. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119138 · Cited by 29
Zhang, J., Hu, J., Chen, B., Zhao, T., & Gu, Z. (2021) · Regenerative Biomaterials · doi:10.1093/rb/rbaa059 · Cited by 29
Uncovering the Metabolic and Stress Responses of Human Embryonic Stem Cells to FTH1 Gene Silencing
Scaramuzzino, L., Lucchino, V., Scalise, S., Conte, M. L., Zannino, C., Sacco, A., Biamonte, F., Parrotta, E. I., Costanzo, F. S., & Cuda, G. (2021) · Cells · doi:10.3390/cells10092431 · Cited by 30
Bhattarai, G., So, H.-S., Kieu, T. T. T., Kook, S., Lee, J., & Jeon, Y. (2021) · Nutrients · doi:10.3390/nu13103575 · Cited by 29
Dissecting in vivo and in vitro redox responses using chemogenetics
Waldeck‐Weiermair, M., Yadav, S., Spyropoulos, F., Krüger, C., Pandey, A. K., & Michel, T. M. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.11.006 · Cited by 29
Metadata
- Authors
- Forrester, S. J., Kikuchi, D. S., Hernandes, M. S., Xu, Q., & Griendling, K. K.
- Affiliations
- Emory University (US)
- Venue
- Circulation Research
- Published
- 2018-03-16
- Volume
- 122
- Issue
- 6
- Pages
- 877-902
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- PMC
- PMC5926825
- OpenAlex
- W2791564057
- Cited by
- 2,081
- References
- 379
- Citations by year
- 2026: 232 · 2025: 300 · 2024: 317 · 2023: 324 · 2022: 316 · 2021: 281 · 2020: 195 · 2019: 97 · 2018: 15
- FWCI
- 14.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- American Heart Association (17SDG33410777)
- National Heart, Lung, and Blood Institute (T32HL007745, P01HL095070)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Keywords
- reactive oxygen species, redox signaling, metabolic regulation, inflammation, signal transduction, mitochondria, peroxisomes, endoplasmic reticulum, proteasome function, autophagy, atherosclerosis, diabetes mellitus, stroke, cardiovascular disease, oxidative stress
- MeSH terms
- Animals, Cardiovascular Diseases, Humans, Metabolic Diseases, Signal Transduction, Reactive Oxygen Species
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review