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Reactive Oxygen Species in Metabolic and Inflammatory Signaling
Open accessAbstract
Reactive oxygen species (ROS) are well known for their role in mediating both physiological and pathophysiological signal transduction. Enzymes and subcellular compartments that typically produce ROS are associated with metabolic regulation, and diseases associated with metabolic dysfunction may be influenced by changes in redox balance. In this review, we summarize the current literature surrounding ROS and their role in metabolic and inflammatory regulation, focusing on ROS signal transduction and its relationship to disease progression. In particular, we examine ROS production in compartments such as the cytoplasm, mitochondria, peroxisome, and endoplasmic reticulum and discuss how ROS influence metabolic processes such as proteasome function, autophagy, and general inflammatory signaling. We also summarize and highlight the role of ROS in the regulation metabolic/inflammatory diseases including atherosclerosis, diabetes mellitus, and stroke. In order to develop therapies that target oxidative signaling, it is vital to understand the balance ROS signaling plays in both physiology and pathophysiology, and how manipulation of this balance and the identity of the ROS may influence cellular and tissue homeostasis. An increased understanding of specific sources of ROS production and an appreciation for how ROS influence cellular metabolism may help guide us in the effort to treat cardiovascular diseases.
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“ROS act as one of the key molecules that regulate inflammatory signaling [52].”
From A tailored bioactive 3D porous poly(lactic-acid)-exosome scaffold with osteo-immunomodulatory and osteogenic differentiation properties (2022) · cites this paper as [52]
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4 retracted
Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
Zhang, H., Bosch-Marce, M., Shimoda, L. A., Tan, Y. S., Baek, J. H., Wesley, J. B., Gonzalez, F. J., & Semenza, G. L. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m800102200 · Cited by 1,601
RetractedMartinez, J., Malireddi, R. K. S., Lu, Q., Cunha, L. D., Pelletier, S., Gingras, S., Orchard, R., Guan, J.-L., Tan, H., Peng, J., et al. (2015) · Nature Cell Biology · doi:10.1038/ncb3192 · Cited by 758
RetractedXu, J., Wu, Y., Song, P., Zhang, M., Wang, S., & Zou, M. (2007) · Circulation · doi:10.1161/circulationaha.106.684795 · Cited by 193
RetractedZou, M., Hou, X., Shi, C., Kirkpatick, S., Liu, F., Goldman, M. H., & Cohen, R. A. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300215200 · Cited by 168
RetractedRepertoires of Autophagy in the Pathogenesis of Ocular Diseases
Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351
How mitochondria produce reactive oxygen species
Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207
Autophagy in the Pathogenesis of Disease
Levine, B., & Kroemer, G. (2008) · Cell · doi:10.1016/j.cell.2007.12.018 · Cited by 7,069
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
Bedard, K., & Krause, K.-H. (2007) · Physiological Reviews · doi:10.1152/physrev.00044.2005 · Cited by 6,989
Ayala, A., Muñoz, M., & Argüelles, S. (2014) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2014/360438 · Cited by 6,837
Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760
Research works printed but not linked: 2
- 10.1172/JCI19451 · DOI · Paper page
- 10.1172/JCI11927 · DOI · Paper page
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Yu, Q., Zheng, Z., Zhang, H., Xie, E., Chen, L., Jiang, Z., Gao, Y., Ma, J., & Yang, L. (2025) · Interdisciplinary medicine · doi:10.1002/inmd.20240062 · Cited by 44
The pathophysiological basis of vascular disease
Lyle, A. N., & Taylor, W. R. (2019) · Laboratory Investigation · doi:10.1038/s41374-019-0192-2 · Cited by 43
Li, X., Zhao, J., Geng, J., Chen, F., Wei, Z., Liu, C., Zhang, X., Li, Q., Zhang, J., Gao, L., et al. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14714 · Cited by 43
Tan, Y., Chen, L.-X., Fang, L., & Zhang, Q. (2020) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-020-03177-y · Cited by 43
Zou, T., Liang, Y., Liao, X.-L., Chen, X.-F., Wang, T., Song, Y., Lin, Z., Qi, Z., Chen, Z., & Cai, Z. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.116665 · Cited by 43
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Xie, X., Zhang, Y., Wang, Z., Wang, S., Jiang, X.-Y., Cui, H., Zhou, T., He, Z., Feng, H., Guo, Q., et al. (2021) · International Journal of Biological Sciences · doi:10.7150/ijbs.63963 · Cited by 44
Zhao, J., Wang, Z., Zhong, M., Xu, Q., Li, X., Chang, B., & Fang, J. (2021) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.1c01362 · Cited by 43
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Luo, H., Urbonaviciute, V., Saei, A. A., Lyu, H., Gaetani, M., Végvári, Á., Li, Y., Zubarev, R. A., & Holmdahl, R. (2023) · JCI Insight · doi:10.1172/jci.insight.164875 · Cited by 42
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Artamonov, M. Y., Мартусевич, А. К., Pyatakovich, F. A., Minenko, I. A., Dlin, S. V., & LeBaron, T. W. (2023) · Antioxidants · doi:10.3390/antiox12030636 · Cited by 42
Mohammadgholi, M., & Hosseinimehr, S. J. (2023) · Current Medicinal Chemistry · doi:10.2174/0929867330666230407104208 · Cited by 42
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Chen, Y., Sung, H., Chuang, T., Lee, T.-L., Lee, C., Lee, I.-T., Lee, I.-T., & Chen, Y. (2021) · Cell Biology and Toxicology · doi:10.1007/s10565-021-09629-6 · Cited by 44
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Zhang, J., Li, R., Man, K., & Yang, X. (2022) · Pharmaceutical Biology · doi:10.1080/13880209.2022.2037664 · Cited by 41
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Yu, Q., Li, J., Yu, Y., Yan, M., Xu, D., & Yin, S. (2024) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2024.216056 · Cited by 41
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Baek, S., Kim, J., Moon, B. S., Park, S. M., Jung, D. E., Kang, S. Y., Lee, S. J., Oh, S. J., Kwon, S. H., Nam, M. H., et al. (2020) · Nutrients · doi:10.3390/nu12123731 · Cited by 39
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Li, X., Liu, C., Li, Y., Yuan, K., Zhang, W., Cai, D., Peng, Z., Hu, Y., Sun, J., & Bai, W. (2023) · Phytochemistry Reviews · doi:10.1007/s11101-023-09890-z · Cited by 40
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Larit, F., León, F., Benyahia, S., & Cutler, S. J. (2019) · Biomolecules · doi:10.3390/biom9110732 · Cited by 38
Sahakyan, N. Z., Andreoletti, P., Cherkaoui‐Malki, M., Petrosyan, M. T., & Trchоunian, A. (2021) · Journal of Food Biochemistry · doi:10.1111/jfbc.13691 · Cited by 38
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Jawale, C. V., Ramani, K., Li, D., Coleman, B. M., Oberoi, R. S., Kupul, S., Lin, L., Desai, J. V., Delgoffe, G. M., Lionakis, M. S., et al. (2020) · Science Translational Medicine · doi:10.1126/scitranslmed.aay5691 · Cited by 38
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Li, H., Liang, X., Chen, Y., Liu, K., Fu, X., Zhang, C., Wang, X., & Yang, J. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10398 · Cited by 38
Dong, J., Ping, L., Meng, Y., Zhang, K., Tang, H., Liu, D., Li, B., & Huo, G. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c02950 · Cited by 36
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Bisaccia, P., Magarotto, F., D’Agostino, S., Dedja, A., Barbon, S., Guidolin, D., Liboni, C., Angioni, R., Lazzari, G. D., Caicci, F., et al. (2023) · Stem Cells Translational Medicine · doi:10.1093/stcltm/szad070 · Cited by 36
Luo, S., Xu, T., Zheng, Q., Jiang, A., Zhao, J., Yue, Y., Liu, N., Pan, Y., & Zhang, D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25020737 · Cited by 36
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Zhen, M., Xu, Y. M., Wang, C., & Bai, C. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202409319 · Cited by 36
Sun, L., Leng, R., Liu, M., Su, M., He, Q., Zhang, Z., Liu, Z., Wang, Z., Jiang, H., Wang, L., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci181928 · Cited by 38
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Muyyarikkandy, M. S., McLeod, M., Maguire, M., Mahar, R., Kattapuram, N., Zhang, C., Surugihalli, C., Muralidaran, V., Vavilikolanu, K., Mathews, C. E., et al. (2020) · The FASEB Journal · doi:10.1096/fj.202001495r · Cited by 37
Hoang, Q. T., Lee, D., Choi, D. G., Kim, Y., & Shim, M. S. (2020) · Journal of Industrial and Engineering Chemistry · doi:10.1016/j.jiec.2020.12.009 · Cited by 36
Zhou, X., Du, H.-H., Ni, L., Ran, J., Hu, J. P., Yu, J., & Zhao, X. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.643089 · Cited by 36
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García‐Rodríguez, C., Tobar, I. D. B., Duarte, Y., Barrio, L. C., & Sáez, J. C. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.107980 · Cited by 36
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Sharapov, M. G., Gudkov, S. V., & Lankin, V. Z. (2021) · Biochemistry (Moscow) · doi:10.1134/s0006297921100084 · Cited by 36
Trujillo-Rangel, W. Á., García-Valdés, L., Villar, M. M.-D., Castañeda‐Arellano, R., Totsuka-Sutto, S. E., & García‐Benavides, L. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/8624318 · Cited by 38
Caruso, F., Incerpi, S., Pedersen, J. Z., Belli, S. L., Kaur, S., & Rossi, M. (2022) · Current Issues in Molecular Biology · doi:10.3390/cimb44110354 · Cited by 38
Reho, J. J., Guo, D., & Rahmouni, K. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.118.010662 · Cited by 35
Sutariya, S., Shah, A. A., Bajpai, A., Sharma, R. J., Pandhurnekar, C. P., & Gupta, A. (2022) · Materials Today Proceedings · doi:10.1016/j.matpr.2022.09.462 · Cited by 35
Benítez, R., Trakooljul, N., Núñez, Y., Isabel, B., Muráni, E., de Mercado, E., Gómez-Izquierdo, E., Casco, J. M. G., López-Bote, C. J., Wimmers, K., et al. (2019) · Genes · doi:10.3390/genes10080589 · Cited by 38
Doerr, V., Montalvo, R. N., Kwon, O. S., Talbert, E. E., Hain, B. A., Houston, F. E., & Smuder, A. J. (2020) · Antioxidants · doi:10.3390/antiox9030263 · Cited by 35
Metadata
- Authors
- Forrester, S. J., Kikuchi, D. S., Hernandes, M. S., Xu, Q., & Griendling, K. K.
- Affiliations
- Emory University (US)
- Venue
- Circulation Research
- Published
- 2018-03-16
- Volume
- 122
- Issue
- 6
- Pages
- 877-902
- ISSN
- 0009-7330 (ISSN-L)
- 1524-4571
- PMC
- PMC5926825
- OpenAlex
- W2791564057
- Cited by
- 2,081
- References
- 379
- Citations by year
- 2026: 232 · 2025: 300 · 2024: 317 · 2023: 324 · 2022: 316 · 2021: 281 · 2020: 195 · 2019: 97 · 2018: 15
- FWCI
- 14.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Circulation Research (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- American Heart Association (17SDG33410777)
- National Heart, Lung, and Blood Institute (T32HL007745, P01HL095070)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Life Sciences › Immunology and Microbiology › Immunology › Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Keywords
- reactive oxygen species, redox signaling, metabolic regulation, inflammation, signal transduction, mitochondria, peroxisomes, endoplasmic reticulum, proteasome function, autophagy, atherosclerosis, diabetes mellitus, stroke, cardiovascular disease, oxidative stress
- MeSH terms
- Animals, Cardiovascular Diseases, Humans, Metabolic Diseases, Signal Transduction, Reactive Oxygen Species
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