The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Patent Foramen Ovale and Stroke
Abstract
A patent foramen ovale (PFO) is common and found in nearly 25% of healthy individuals. The majority of patients with PFO remain asymptomatic and they are not at increased risk for developing a stroke. The presence of PFO, however, has been found to be higher in patients with cryptogenic stroke, suggesting there may be a subset of patients with PFO who are indeed at risk for stroke. Paradoxical embolization of venous thrombi through the PFO, which then enter the arterial circulation, is hypothesized to account for this relationship. Although aerated-saline transesophageal echocardiography is the gold standard for diagnosis, aerated-saline transthoracic echocardiography and transcranial Doppler are often used as the initial diagnostic tests for detecting PFO. Patients with cryptogenic stroke and PFO are generally treated with antiplatelet therapy in the absence of another condition for which anticoagulation is necessary. Based on the findings of 3 large randomized clinical trials, current consensus guidelines do not recommend percutaneous closure, though this is an area of controversy. The following review discusses the relationship of PFO and cryptogenic stroke, focusing on the epidemiology, pathophysiological mechanisms, diagnostic tools, associated clinical/anatomic factors and treatment. (Circ J 2016; 80: 1665-1673).
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Hagen, P. T., SCHOLZ, D. G., & Edwards, W. D. (1984) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)60336-x · Cited by 2,528
Prevalence of Patent Foramen Ovale in Patients with Stroke
Lechat, P., Mas, J. L., Lascault, G., Loron, P., Theard, M., Klimczac, M., Drobinski, G., Thomas, D., & Grosgogeat, Y. (1988) · New England Journal of Medicine · doi:10.1056/nejm198805053181802 · Cited by 1,657
Mas, J.-L., Arquizan, C., Lamy, C., Zuber, M., Cabanes, L., Derumeaux, G., & Coste, J. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011503 · Cited by 1,361
A comparison of warfarin and aspirin for the prevention of recurrent ischemic stroke
Mohr, J. P., Thompson, J. L. P., Lazar, R. M., Levin, B., Sacco, R. L., Furie, K. L., Kistler, J. P., Albers, G. W., Pettigrew, L. C., Adams, H. P., et al. (2001) · New England Journal of Medicine · doi:10.1056/nejmoa011258 · Cited by 1,168
Self-citationHemorrhagic Complications of Anticoagulant Treatment
Levine, M. N., Raskob, G., Landefeld, S., & Kearon, C. (2001) · Chest · doi:10.1378/chest.119.1_suppl.108s · Cited by 1,134
Homma, S., Sacco, R. L., Di Tullio, M. R., Sciacca, R. R., & Mohr, J. P. (2002) · Circulation · doi:10.1161/01.cir.0000017498.88393.44 · Cited by 949
Self-citationInteratrial septal abnormalities and stroke: A meta-analysis of case-control studies
Overell, J. R., Bone, I., & Lees, K. R. (2000) · Neurology · doi:10.1212/wnl.55.8.1172 · Cited by 936
PATENT FORAMEN OVALE IN YOUNG STROKE PATIENTS
Webster, M. W. I., Smith, H. J., Sharpe, D. N., Chancellor, A. M., Swift, D. L., Bass, N. M., & Glasgow, G. L. (1988) · The Lancet · doi:10.1016/s0140-6736(88)92944-3 · Cited by 823
Infarcts of undetermined cause: The NINCDS stroke data bank
Sacco, R. L., Ellenberg, J. H., Mohr, J. P., Tatemichi, T. K., Hier, D. B., Price, T. R., & Wolf, P. A. (1989) · Annals of Neurology · doi:10.1002/ana.410250410 · Cited by 767
Self-citationGo, A. S., Hylek, E. M., Chang, Y., Phillips, K. A., Henault, L. E., Capra, A. M., Jensvold, N. G., Selby, J. V., & Singer, D. E. (2003) · JAMA · doi:10.1001/jama.290.20.2685 · Cited by 703
Metadata
- Authors
- Homma, S., & Sacco, R. L.
- Venue
- Circulation
- Published
- 2005-08-16
- Volume
- 112
- Issue
- 7
- Pages
- 1063-1072
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2152957878
- Cited by
- 435
- References
- 54
- FWCI
- 17.51
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
