Cited by 844Congenital Heart Disease StudiesCongenital heart defects researchPrenatal Substance Exposure Effects

The DOI matches its Crossref record; 232 of the 232 references it cites were found in a registry or an index.

Noninherited Risk Factors and Congenital Cardiovascular Defects: Current Knowledge: A Scientific Statement From the American Heart Association Council on Cardiovascular Disease in the Young: Endorsed by the American Academy of Pediatrics

Jenkins, Kathy J., Correa, Adolfo, Feinstein, Jeffrey A., Botto, Lorenzo, Britt, Amy E., Daniels, Stephen R., Elixson, Marsha, Warnes, Carole A., Webb, Catherine L.·2007·Circulation

DOI 10.1161/circulationaha.106.183216

Open this paper in CoChat — free account

Abstract

Prevention of congenital cardiovascular defects has been hampered by a lack of information about modifiable risk factors for abnormalities in cardiac development. Over the past decade, there have been major breakthroughs in the understanding of inherited causes of congenital heart disease, including the identification of specific genetic abnormalities for some types of malformations. Although relatively less information has been available on noninherited modifiable factors that may have an adverse effect on the fetal heart, there is a growing body of epidemiological literature on this topic. This statement summarizes the currently available literature on potential fetal exposures that might alter risk for cardiovascular defects. Information is summarized for periconceptional multivitamin or folic acid intake, which may reduce the risk of cardiac disease in the fetus, and for additional types of potential exposures that may increase the risk, including maternal illnesses, maternal therapeutic and nontherapeutic drug exposures, environmental exposures, and paternal exposures. Information is highlighted regarding definitive risk factors such as maternal rubella; phenylketonuria; pregestational diabetes; exposure to thalidomide, vitamin A cogeners, or retinoids; and indomethacin tocolysis. Caveats regarding interpretation of possible exposure-outcome relationships from case-control studies are given because this type of study has provided most of the available information. Guidelines for prospective parents that could reduce the likelihood that their child will have a major cardiac malformation are given. Issues related to pregnancy monitoring are discussed. Knowledge gaps and future sources of new information on risk factors are described.

Integrity signals

Registry

Crossref · 10.1161/circulationaha.106.183216

Cites

232 of 232 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Heart Disease and Stroke Statistics—2007 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Rosamond, W., Flegal, K., Friday, G., Furie, K., Go, A., Greenlund, K., Haase, N., Ho, M., Howard, V., Kissela, B., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.179918 · Cited by 3,277
The Continuing Epidemics of Obesity and Diabetes in the United States
Mokdad, A. H. (2001) · JAMA · doi:10.1001/jama.286.10.1195 · Cited by 2,730
Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988–1994
Harris, M. I., Flegal, K. M., Cowie, C. C., Eberhardt, M. S., Goldstein, D. E., Little, R. R., Wiedmeyer, H.-M., & Byrd-Holt, D. D. (1998) · Diabetes Care · doi:10.2337/diacare.21.4.518 · Cited by 2,703
Gestational diabetes mellitus
Buchanan, T. A., & Xiang, A. H. (2005) · Journal of Clinical Investigation · doi:10.1172/jci200524531 · Cited by 2,123
Maternal Pesticide Exposure from Multiple Sources and Selected Congenital Anomalies
Shaw, G. M., Wasserman, C. R., O’Malley, C. D., Nelson, V. E., & Jackson, R. J. (1999) · Epidemiology · doi:10.1097/00001648-199901000-00011 · Cited by 1,783
The Fetal Alcohol Syndrome
Clarren, S. K., & Smith, D. W. (1978) · New England Journal of Medicine · doi:10.1056/nejm197805112981906 · Cited by 1,359
Major congenital malformations after first-trimester exposure to ACE inhibitors
Cooper, W. O., Hernandez-Diaz, S., Arbogast, P. G., Dudley, J. A., Dyer, S., Gideon, P. S., Hall, K., & Ray, W. A. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa055202 · Cited by 1,192
CONGENITAL HEART DISEASE: PREVALENCE AT LIVEBIRTH
Ferencz, C., Rubin, J. D., McCarter, R., Brenner, J. I., Neill, C. A., Perry, L. W., Hepner, S. I., & Downing, J. W. (1985) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113979 · Cited by 1,025
Congenital Cataract Following German Measles in the Mother
Gregg, N. M. (1941) · Springer eBooks · doi:10.1007/978-94-011-6621-8_22 · Cited by 888
Genetic Basis for Congenital Heart Defects: Current Knowledge
Pierpont, M. E., Basson, C. T., Benson, D. W., Gelb, B. D., Giglia, T. M., Goldmuntz, E., McGee, G., Sable, C., Srivastava, D., & Webb, C. L. (2007) · Circulation · doi:10.1161/circulationaha.106.183056 · Cited by 850
Self-citation

Show all 232 references

Research works printed but not linked: 7

Gregg NM. Further observations on congenital defects in infants following maternal rubella. Trans Ophthalmol Soc Aust. 1944; 4: 119–131.
10.1161/circ.56.1.301070 · DOI
Bracken MB. Drug use in pregnancy and congenital heart disease in offspring. N Engl J Med. 1986; 314: 1120.
10.1001/jama.1981.03320040015021 · DOI
Netter JC, Choulot JJ, Dagues-Bie M. Oligohydramnios and persistent pulmonary arterial hypertension after use of ketoprofen during pregnancy. Sem Hop Paris. 1990; 66: 1953–1954.Abstract.
10.1097/00001648-199909000-00008 · DOI
10.1161/circ.47.2.359 · DOI

Sorted by citations

Items 301–400 of 844

Nanofiber composites in vascular tissue engineering
Fukunishi, T., Shoji, T., & Shinoka, T. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-100173-8.00018-1 · Cited by 25
A pilot study of paternal drug exposure: The Motherisk experience
Lee, C. Y. W., Jin, C. S., Mata, A. M., Tanaka, T., Einarson, A., & Koren, G. (2010) · Reproductive Toxicology · doi:10.1016/j.reprotox.2010.01.008 · Cited by 24
Factores asociados a la supervivencia al año de vida en neonatos con cardiopatía congénita severa en un hospital nacional de Perú
Torres-Romucho, C. E., Uriondo-Ore, V. G., Ramirez-Palomino, A. J., Arroyo-Hernández, H., Loo-Valverde, M., Pinedo, A. P., & Dueñas, M. (2019) · Revista Peruana de Medicina Experimental y Salud Pública · doi:10.17843/rpmesp.2019.363.4166 · Cited by 24
Geotemporospatial and causal inferential epidemiological overview and survey of USA cannabis, cannabidiol and cannabinoid genotoxicity expressed in cancer incidence 2003–2017: part 2 – categorical bivariate analysis and attributable fractions
Reece, A. S., & Hulse, G. K. (2022) · Archives of Public Health · doi:10.1186/s13690-022-00812-7 · Cited by 24
Germline hereditary, somatic mutations and microRNAs targeting-SNPs in congenital heart defects
Sabina, S., Pulignani, S., Rizzo, M., Cresci, M., Vecoli, C., Foffa, I., Ait-Alì, L., Pitto, L., & Andreassi, M. G. (2013) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2013.04.002 · Cited by 24
Identification of two novel GATA6 mutations in patients with nonsyndromic conotruncal heart defects
Wang, X., Ji, W., Wang, J., Zhao, P., Guo, Y., Xu, R., CHEN, S., & Sun, K. (2014) · Molecular Medicine Reports · doi:10.3892/mmr.2014.2247 · Cited by 24
Is the Rate of Congenital Heart Defects Detected by Fetal Echocardiography Among Pregnancies Conceived by In Vitro Fertilization Really Increased?
Bahtiyar, M. O., Campbell, K. H., Dulay, A. T., Kontić‐Vučinić, O., Weeks, B. P., Friedman, A. H., & Copel, J. A. (2010) · Journal of Ultrasound in Medicine · doi:10.7863/jum.2010.29.6.917 · Cited by 24
HAND1 loss-of-function mutation contributes to congenital double outlet right ventricle
Li, L., Wang, J., Liu, X., Liu, H., Shi, H., Yang, X., Li, N., Li, Y., Huang, R., Xue, S., et al. (2017) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2017.2865 · Cited by 24
Nationwide Increase in Complex Congenital Heart Diseases After the Fukushima Nuclear Accident
Murase, K., Murase, J., & Mishima, A. (2019) · Journal of the American Heart Association · doi:10.1161/jaha.118.009486 · Cited by 24
Mutations inNTRK3Suggest a Novel Signaling Pathway in Human Congenital Heart Disease
Werner, P., Paluru, P. C., Simpson, A. M., Latney, B., Iyer, R., Brodeur, G. M., & Goldmuntz, E. (2014) · Human Mutation · doi:10.1002/humu.22688 · Cited by 24
Current diagnosis and treatments for critical congenital heart defects
Zeng, Z., Zhang, H., Liu, F., & Zhang, N. (2016) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2016.3167 · Cited by 23
Genetic polymorphisms in MTR are associated with non-syndromic congenital heart disease from a family-based case-control study in the Chinese population
Deng, C., Deng, Y., Xie, L., Li, Y., Liu, L., Liu, H., & Dai, L. (2019) · Scientific Reports · doi:10.1038/s41598-019-41641-z · Cited by 23
FOXD3-AS1 Knockdown Suppresses Hypoxia-Induced Cardiomyocyte Injury by Increasing Cell Survival and Inhibiting Apoptosis via Upregulating Cardioprotective Molecule miR-150-5p In Vitro
Zheng, J., Peng, B., Zhang, Y., Ai, F., & Hu, X. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01284 · Cited by 23
The effect of maternal BMI, smoking and alcohol on congenital heart diseases: a Mendelian randomisation study
Taylor, K., Wootton, R. E., Yang, Q., Oddie, S., Wright, J., Yang, T., Magnus, M. C., Andreassen, O. A., Borges, M. C., Caputo, M., et al. (2023) · BMC Medicine · doi:10.1186/s12916-023-02731-y · Cited by 24
Influence of substance use on male reproductive health and offspring outcomes
Lo, J. O.-T., Hedges, J. C., Chou, W. H., Tager, K. R., Bachli, I., Hagen, O. L., Murphy, S. K., Hanna, C. B., & Easley, C. A. (2024) · Nature Reviews Urology · doi:10.1038/s41585-024-00868-w · Cited by 23
Comparison of Coping Strategy and Disease Knowledge in Dyads of Parents and Their Adolescent With Congenital Heart Disease
Ahn, J., Lee, S., & Choi, J. Y. (2013) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0000000000000090 · Cited by 23
Maximizing the Impact of Flour Fortification to Improve Vitamin and Mineral Nutrition in Populations
Serdula, M. K. (2010) · Food and Nutrition Bulletin · doi:10.1177/15648265100311s108 · Cited by 23
Critical congenital heart defects and abnormal levels of routinely collected first‐ and second‐trimester biomarkers
Borrelli, M., Baer, R. J., Chambers, C., Smith, T. C., & Jelliffe‐Pawlowski, L. L. (2016) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.38013 · Cited by 23
Identification of TBX2 and TBX3 variants in patients with conotruncal heart defects by target sequencing
Xie, H., Zhang, E., Hong, N., Fu, Q., Li, F., Chen, S., Yu, Y., & Sun, K. (2018) · Human Genomics · doi:10.1186/s40246-018-0176-0 · Cited by 23
The Epidemiology of Cardiovascular Malformations
Wren, C. (2012) · Wiley eBooks · doi:10.1002/9781444398786.ch19 · Cited by 23
Novel NKX2-5 mutations responsible for congenital heart disease
Wang, J., Liu, X. Y., & Yang, Y. Q. (2011) · Genetics and Molecular Research · doi:10.4238/2011.november.29.1 · Cited by 23
Evaluation of Potential Modifiers of the Palatal Phenotype in the 22q11.2 Deletion Syndrome
Driscoll, D. A., Boland, T. A., Emanuel, B. S., Kirschner, R. E., LaRossa, D., Manson, J. M., McDonald‐McGinn, D. M., Randall, P., Solot, C. B., Zackai, E. H., et al. (2006) · The Cleft Palate-Craniofacial Journal · doi:10.1597/05-070.1 · Cited by 23
Association of congenital cardiovascular malformations with 33 single nucleotide polymorphisms of selected cardiovascular disease–related genes
KUEHL, K. S., Loffredo, C. A., Lammer, E. J., Iovannisci, D. M., & Shaw, G. M. (2009) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20630 · Cited by 23
Uncovering the Genetic Basis of Congenital Heart Disease: Recent Advancements and Implications for Clinical Management
Chhatwal, K., Smith, J. J., Bola, H., Zahid, A., Venkatakrishnan, A., & Brand, T. (2023) · CJC Pediatric and Congenital Heart Disease · doi:10.1016/j.cjcpc.2023.10.008 · Cited by 22
Genetic Counseling in the Adult with Congenital Heart Disease: What is the Role?
Burchill, L. J., Greenway, S. C., Silversides, C. K., & Mital, S. R. (2011) · Current Cardiology Reports · doi:10.1007/s11886-011-0188-z · Cited by 22
Spectrum of fetal echocardiographic findings in fetuses of women with clinical or serologic evidence of systemic lupus erythematosus
Krishnan, A. N., Sable, C., & Donofrio, M. T. (2008) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767050802388446 · Cited by 22
Geospatiotemporal and causal inference study of cannabis and other drugs as risk factors for female breast cancer USA 2003–2017
Reece, A. S., & Hulse, G. K. (2022) · Current Zoology · doi:10.1093/eep/dvac006 · Cited by 21
Prevalence of Congenital Heart Disease in Chinese Children With Different Birth Weights and Its Relationship to the Neonatal Birth Weight
Yan, H., Zhai, B., Feng, R., Wang, P., Zhang, Y., Wang, Y., Hou, Y., & Zhou, Y. (2022) · Frontiers in Pediatrics · doi:10.3389/fped.2022.828300 · Cited by 21
Maternal Preconception Hepatitis B Virus Infection and Risk of Congenital Heart Diseases in Offspring Among Chinese Women Aged 20 to 49 Years
Wu, H., Yang, Y., Jia, J., Guo, T., Lei, J., Deng, Y., He, Y., Wang, Y., Peng, Z., Zhang, Y., et al. (2023) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2023.0053 · Cited by 21
Epidemiology and Prevention of Congenital Heart Defects
Botto, L. D. (2015) · KARGER eBooks · doi:10.1159/000375203 · Cited by 21
Self-citation
Cigarette Smoking Impairs Adipose Stromal Cell Vasculogenic Activity and Abrogates Potency to Ameliorate Ischemia
Barwinska, D., Traktuev, D. O., Merfeld‐Clauss, S., Cook, T. G., Lu, H., Petrache, I., & March, K. L. (2018) · Stem Cells · doi:10.1002/stem.2813 · Cited by 21
Intake of sucrose-sweetened soft beverages during pregnancy and risk of congenital heart defects (CHD) in offspring: a Norwegian pregnancy cohort study
Dale, M. T. G., Magnus, P. M., Leirgul, E., Holmstrøm, H., Gjessing, H. K., Brodwall, K., Haugen, M. A., Stoltenberg, C., & Øyen, N. (2019) · European Journal of Epidemiology · doi:10.1007/s10654-019-00480-y · Cited by 21
The Association of Folic Acid, Iron Nutrition during Pregnancy and Congenital Heart Disease in Northwestern China: A Matched Case-Control Study
Yan, M., Zhao, Y., Zhao, D., Dang, S., Zhang, R., Duan, X.-Y., Rong, P., Dang, Y.-S., Pei, L., & Qu, P. (2022) · Nutrients · doi:10.3390/nu14214541 · Cited by 21
Congenital heart disease and chromossomopathies detected by the karyotype
Trevisan, P., Rosa, R. F. M., Koshiyama, D. B., Zen, T. D., Paskulin, G. A., & Zen, P. R. G. (2014) · Revista Paulista de Pediatria · doi:10.1590/0103-0582201432213213 · Cited by 21
Association between maternal marginalization and infants born with congenital heart disease in Ontario Canada
Miao, Q., Dunn, S., Wen, S. W., Lougheed, J., Yang, P., Davies, M. J., Venegas, C. L., & WALKER, M. C. (2023) · BMC Public Health · doi:10.1186/s12889-023-15660-5 · Cited by 20
In-Depth Genomic Analysis: The New Challenge in Congenital Heart Disease
Nappi, F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25031734 · Cited by 20
Maternal Reproductive History and the Risk of Congenital Heart Defects in Offspring: A Systematic Review and Meta-analysis
Feng, Y., Wang, S., Zhao, L., Yu, D., Hu, L., & Mo, X. (2014) · Pediatric Cardiology · doi:10.1007/s00246-014-1079-z · Cited by 20
MTHFR c.1793G>A polymorphism is associated with congenital cardiac disease in a Chinese population
Xu, J., Xu, X., Xue, L., Liu, X., Gu, H., Cao, H., Qiu, W., Hu, Z., Shen, H., & Chen, Y. (2010) · Cardiology in the Young · doi:10.1017/s1047951110000247 · Cited by 20
Evaluation of risk due to chronic low dose ionizing radiation exposure on the birth prevalence of congenital heart diseases (CHD) among the newborns from high-level natural radiation areas of Kerala coast, India
Sudheer, K. R., Koya, P. K. M., Prakash, A. J., Prakash, A. M., Kumar, R. M., Shyni, S. S., Jagadeesan, C. K., Jaikrishan, G., & Das, B. (2022) · Genes and Environment · doi:10.1186/s41021-021-00231-0 · Cited by 20
Association of certain chronic maternal diseases with the risk of specific congenital heart defects: a population-based study
Vereczkey, A., Gerencsér, B. S., Czeizel, A. E., & Szabó, I. (2014) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2014.08.022 · Cited by 20
Accelerated Cardiac Aging in Patients With Congenital Heart Disease
Iacobazzi, D., Alvino, V. V., Caputo, M., & Madeddu, P. R. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.892861 · Cited by 19
Pediatric robotic surgery: issues in management—expert consensus from the Italian Society of Pediatric and Neonatal Anesthesia and Intensive Care (SARNePI) and the Italian Society of Pediatric Surgery (SICP)
Tesoro, S., Gamba, P., Bertozzi, M., Borgogni, R., Caramelli, F., Cobellis, G., Cortese, G., Esposito, C., Gargano, T., Garra, R., et al. (2022) · Surgical Endoscopy · doi:10.1007/s00464-022-09577-0 · Cited by 19
Epigenomic and Other Evidence for Cannabis-Induced Aging Contextualized in a Synthetic Epidemiologic Overview of Cannabinoid-Related Teratogenesis and Cannabinoid-Related Carcinogenesis
Reece, A. S., & Hulse, G. K. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192416721 · Cited by 19
Collagen gel analysis of epithelial–mesenchymal transition in the embryo heart: An in vitro model system for the analysis of tissue interaction, signal transduction, and environmental effects
Lencinas, A., Tavares, A. L. P., Barnett, J. V., & Runyan, R. B. (2011) · Birth Defects Research Part C Embryo Today Reviews · doi:10.1002/bdrc.20222 · Cited by 19
HAND1 Loss-of-Function Mutation Causes Tetralogy of Fallot
Wang, J., Hu, X.-Q., Guo, Y., Gu, J.-Y., Xu, J., Li, Y., Li, N., Yang, X., & Yang, Y. (2016) · Pediatric Cardiology · doi:10.1007/s00246-016-1547-8 · Cited by 19
Association of Maternal Diabetes Mellitus and Polymorphisms of theNKX2.5Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study
Zhao, M., Diao, J., Huang, P., Li, J., Li, Y., Yang, Y., Luo, L., Zhang, S., Chen, L., Wang, T., et al. (2020) · Journal of Diabetes Research · doi:10.1155/2020/3854630 · Cited by 19
Probing Human Cardiovascular Congenital Disease Using Transgenic Mouse Models
Snider, P. L., & Conway, S. J. (2011) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-384878-9.00003-0 · Cited by 20
The Heart
Schöen, F. J., & Mitchell, R. N. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4377-0792-2.50017-1 · Cited by 19
A study of serum levels of leptin, ghrelin and tumour necrosis factor-alpha in child patients with cyanotic and acyanotic, congenital heart disease.
Shahramian, I., Noori, N. M., Hashemi, M. M., Sharafi, E., & Baghbanian, A. (2013) · PubMed · Cited by 18
The Placenta in Congenital Heart Disease: Form, Function and Outcomes
Josowitz, R., Linn, R. L., & Rychik, J. R. (2023) · NeoReviews · doi:10.1542/neo.24-9-e569 · Cited by 18
Cytogenomic Evaluation of Subjects with Syndromic and Nonsyndromic Conotruncal Heart Defects
de Souza, K. R. S., Mergener, R., Huber, J., Pellanda, L. C., & Riegel, M. (2015) · BioMed Research International · doi:10.1155/2015/401941 · Cited by 18
Extraction of the fetal ECG in noninvasive recordings by signal decompositions
Christov, I. I., Simova, I. I., & Abächerli, R. (2014) · Physiological Measurement · doi:10.1088/0967-3334/35/8/1713 · Cited by 18
Isolated atrioventricular canal defects: Birth outcomes and risk factors: A population‐based hungarian case–control study, 1980–1996
Vereczkey, A., Kósa, Z., Csáky‐Szunyogh, M., & Czeizel, A. E. (2013) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.23124 · Cited by 18
Novel mutations of AXIN2 identified in a Chinese Congenital Heart Disease Cohort
Zhu, M.-J., Ma, X., Ding, P., Tang, H., Peng, R., Lü, L., Li, P., Qiao, B., Yang, X., Zheng, Y., et al. (2019) · Journal of Human Genetics · doi:10.1038/s10038-019-0572-x · Cited by 18
Association between maternal exposure to pollutant particulate matter 2.5 and congenital heart defects: a systematic review
Hall, K. C., & Robinson, J. C. (2019) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2017-003881 · Cited by 18
Pregnancy outcomes of fetuses with congenital heart disease after a prenatal diagnosis with chromosome microarray
Zhang, Z., Hu, T., Wang, J., Hu, R. M., Li, Q., Xiao, L., Liao, N., Liu, Z., Wang, H., & Liu, S. (2021) · Prenatal Diagnosis · doi:10.1002/pd.6078 · Cited by 18
Risk Factors in the Origin of Congenital Left-Ventricular Outflow-Tract Obstruction Defects of the Heart: A Population-Based Case–Control Study
Csáky‐Szunyogh, M., Vereczkey, A., Kósa, Z., Gerencsér, B. S., & Czeizel, A. E. (2013) · Pediatric Cardiology · doi:10.1007/s00246-013-0749-6 · Cited by 18
Birth Defects Surveillance in the United States: Challenges and Implications of International Classification of Diseases, Tenth Revision, Clinical Modification Implementation
Mburia‐Mwalili, A., & Yang, W. Y. L. (2014) · International Scholarly Research Notices · doi:10.1155/2014/212874 · Cited by 18
Is the Prevalence of Specific Types of Congenital Heart Defects Different for Non-Hispanic White, Non-Hispanic Black and Hispanic Infants?
Nembhard, W. N., Salemi, J. L., Wang, T., Loscalzo, M. L., & Hauser, K. W. (2009) · Maternal and Child Health Journal · doi:10.1007/s10995-009-0442-9 · Cited by 18
Uric acid: a potent molecular contributor to pluripotent stem cell cardiac differentiation via mesoderm specification
Ke, B., Zeng, Y., Zhao, Z., Han, F., Liu, T., Wang, J., Khalique, A., Lu, W., Chong, J. J. H., Lan, F., et al. (2018) · Cell Death and Differentiation · doi:10.1038/s41418-018-0157-9 · Cited by 18
Case-control analysis of maternal prenatal analgesic use and cardiovascular malformations: Baltimore–Washington Infant Study
Marsh, C. A., Cragan, J. D., Alverson, C. J., & Correa, A. (2014) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2014.03.054 · Cited by 18
Self-citation
Using Zebrafish to Analyze the Genetic and Environmental Etiologies of Congenital Heart Defects
Shrestha, R., Lieberth, J., Tillman, S., Natalizio, J., & Bloomekatz, J. E. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-2389-2_8 · Cited by 17
Triclosan in paired-maternal and cord blood, and their relationships with congenital heart disease of baby
Luan, Y.-L., Ou, Y., Liu, X.-Q., Lin, S., & Guo, Y. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.159205 · Cited by 17
Systematic Review and Meta-analysis of Prenatal Risk Factors for Congenital Heart Disease: Part 1, Maternal Chronic Diseases and Parental Exposures
Khalilipalandi, S., Lemieux, A., Lauzon-Schnittka, J., Perreault, L., Dubois, M., Tousignant, A., Watelle, L., Pratte, G., & Dallaire, F. (2024) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2024.07.004 · Cited by 17
Meta-Analysis of Risk Factors for Congenital Heart Disease: Part 2, Maternal Medication, Reproductive Technologies, and Familial and Fetal Factors
Lemieux, A., Khalilipalandi, S., Lauzon-Schnittka, J., Taillefer, V., Tousignant, A., Perreault, L., Rego, K., Dubois, M., Watelle, L., Roy, L.-O., et al. (2024) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2024.09.011 · Cited by 17
Variants of folate metabolism genes and risk of left‐sided cardiac defects
Mitchell, L. E., Long, J., Garbarini, J. L., Paluru, P. C., & Goldmuntz, E. (2009) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20622 · Cited by 17
Pregnancy and fetal outcomes after paternal exposure to azathioprine, methotrexate or mycophenolic acid: a critically appraised topic
Garritsen, F. M., van den Broek, M. P. H., van Zuilen, A. D., Fidder, H. H., de Bruin-Weller, M. S., & Spuls, P. I. (2017) · British Journal of Dermatology · doi:10.1111/bjd.15320 · Cited by 17
Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling
Xie, Y., Ma, A., Wang, B., Peng, R., Jing, Y., Wang, D., Finnell, R. H., Qiao, B., Wang, Y., Wang, H., et al. (2019) · Clinical Science · doi:10.1042/cs20180842 · Cited by 17
Electrical Stimulation of pediatric cardiac-derived c-kit+ progenitor cells improves retention and cardiac function in right ventricular heart failure
Maxwell, J. T., Trac, D. Q., Shen, M., Brown, M. E., Davis, M. E., Chao, M. S., Supapannachart, K. J., Zaladonis, C. A., Baker, E., Li, M. L., et al. (2019) · Stem Cells · doi:10.1002/stem.3088 · Cited by 17
Associations between ambient heat exposure early in pregnancy and risk of congenital heart defects: a large population-based study
Yu, X., Miao, H., Zeng, Q., Wu, H., Chen, Y., Guo, P., & Zhu, Y. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-16237-8 · Cited by 17
Human-derived decellularized extracellular matrix scaffold incorporating autologous bone marrow stem cells from patients with congenital heart disease for cardiac tissue engineering
Gao, L., Li, X., Tan, R., Cui, J., & Schmull, S. (2022) · Bio-Medical Materials and Engineering · doi:10.3233/bme-211368 · Cited by 17
Gestational and family risk factors for carriers of congenital heart defects in southern Brazil
Zen, T. D., Rosa, R. F. M., Zen, P. R. G., Trevisan, P., da Silva, A. P., Ricachinevsky, C. P., & Paskulin, G. A. (2011) · Pediatrics International · doi:10.1111/j.1442-200x.2011.03341.x · Cited by 17
Maternal Environmental Exposure, Infant GSTP1 Polymorphism, and Risk of Isolated Congenital Heart Disease
Cresci, M., Foffa, I., Ait-Alì, L., Pulignani, S., Kemeny, A., Gianicolo, E., & Andreassi, M. G. (2012) · Pediatric Cardiology · doi:10.1007/s00246-012-0436-z · Cited by 17
Hyperglycemia Alters the Structure and Hemodynamics of the Developing Embryonic Heart
Lawson, T., Scott, D. E., Chivukula, V. K., Rugonyi, S., Thornburg, K. L. R., & Hinds, M. T. (2018) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd5010013 · Cited by 17
Gingival evaluation of the pediatric cardiac patient.
Nosrati, E., Eckert, G. J., Kowolik, M. J., Ho, J. G., Schamberger, M. S., & Kowolik, J. E. (2013) · PubMed · Cited by 17
Simple Cardiac Shunts in Adults
Berko, N. S., & Haramati, L. B. (2012) · Seminars in Roentgenology · doi:10.1053/j.ro.2011.12.003 · Cited by 16
Indigenous Ethnicity and Low Maternal Education Are Associated with Delayed Diagnosis and Mortality in Infants with Congenital Heart Defects in Panama
Castro, F., Cisneros, J. Z., Higuera, G., Donderis, M. C., Gómez, B., & Motta, J. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0163168 · Cited by 16
Imprinting aberrations of SNRPN, ZAC1 and INPP5F genes involved in the pathogenesis of congenital heart disease with extracardiac malformations
Zhao, X., Chang, S., Liu, X., Wang, S., Zhang, Y., Lü, X., Zhang, T., Zhang, H., & Wang, L. (2020) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.15584 · Cited by 16
Association between prepregnancy body mass index and risk of congenital heart defects in offspring: an ambispective observational study in China
Yuan, X., Liu, Z., Zhu, J., Yu, P., Deng, Y., Chen, X., Li, N., Li, S., Yang, S., Li, J., et al. (2020) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-020-03100-w · Cited by 16
Towards scaling Twitter for digital epidemiology of birth defects
Klein, A. Z., Sarker, A., Weissenbacher, D., & Gonzalez‐Hernandez, G. (2019) · npj Digital Medicine · doi:10.1038/s41746-019-0170-5 · Cited by 16
Maternal fever during preconception and conception is associated with congenital heart diseases in offspring
Yang, G., Deng, X., Xiao, J., Huang, P., Zhang, K., & Li, Y. (2021) · Medicine · doi:10.1097/md.0000000000024899 · Cited by 16
Culture Medium and Sex Drive Epigenetic Reprogramming in Preimplantation Bovine Embryos
Cánovas, S., Ivanova, E., Hamdi, M., Pérez-Sánz, F., Rizos, D. V., Kelsey, G., & Coy, P. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126426 · Cited by 16
Impact of Mendelian inheritance in cardiovascular disease
McBride, K. L., & Garg, V. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05791.x · Cited by 16
Drugs in pregnancy: Implications for a cardiologist.
Rakusan, K. (2010) · Europe PMC (PubMed Central) · Cited by 16
Haploinsufficiency of insulin gene enhancer protein 1 (ISL1) is associated with d‐transposition of the great arteries
Osoegawa, K., Schultz, K., Yun, K., Mohammed, N., Shaw, G. M., & Lammer, E. J. (2014) · Molecular Genetics & Genomic Medicine · doi:10.1002/mgg3.75 · Cited by 16
Interpregnancy interval and birth defects
Mburia‐Mwalili, A., & Yang, W. Y. L. (2015) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.23420 · Cited by 16
The developing embryonic cardiac outflow tract is highly sensitive to oxidant stress
Fisher, S. A. (2007) · Developmental Dynamics · doi:10.1002/dvdy.21373 · Cited by 16
Maternal Obesity as a Risk Factor for the Development of Total Anomalous Pulmonary Venous Connection in Their Offspring
Alvarado-Terrones, E. G., Perea‐Cabrera, M., Klünder‐Klünder, M., Segura‐Stanford, B., Erdmenger‐Orellana, J., Blanco, A. L.-Y., Hernández-Carbajal, E., Riverón, J. T. G., Mejía-Marín, L. J., Balderrábano-Saucedo, N., et al. (2018) · Archives of Medical Research · doi:10.1016/j.arcmed.2018.06.001 · Cited by 16
Ethical issues raised by incorporation of genetics into the National Birth Defects Prevention Study
Jenkins, M. M., Rasmussen, S. A., Moore, C. A., & Honein, M. A. (2008) · American Journal of Medical Genetics Part C Seminars in Medical Genetics · doi:10.1002/ajmg.c.30157 · Cited by 16
SUMO conjugation and cardiovascular development
Wang, J. (2009) · Frontiers in bioscience · doi:10.2741/3304 · Cited by 16
Pregestational Diabetes Mellitus and Congenital Heart Defects
Correa, A. (2016) · Circulation · doi:10.1161/circulationaha.116.022960 · Cited by 16
Self-citation
Understanding the Genetic and Non-genetic Interconnections in the Aetiology of Isolated Congenital Heart Disease: An Updated Review: Part 1
Maddhesiya, J., & Mohapatra, B. (2024) · Current Cardiology Reports · doi:10.1007/s11886-024-02022-9 · Cited by 15
Curcumin-Mediated Cardiac Defects in Mouse is Associated with a Reduced Histone H3 Acetylation and Reduced Expression of Cardiac Transcription Factors
Sun, H., Zhu, J., Lu, T., Huang, X., & Tian, J. (2013) · Cardiovascular Toxicology · doi:10.1007/s12012-013-9240-0 · Cited by 15
Noninvasive prenatal testing for congenital heart disease – cell-free nucleic acid and protein biomarkers in maternal blood
Biró, O., Rigó, J. J., & Nagy, B. (2018) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2018.1508437 · Cited by 15
The Incidence of Congenital Heart Defects in Offspring Among Women With Diabetes in Saudi Arabia
Alyousif, S. M., Aldokhel, F. T., Alkhanbashi, O. K., Alqahtani, M. H. A., Aladawi, A. M. M., Ashmawi, A. A., Alqunaibet, A., & Masuadi, E. (2021) · Cureus · doi:10.7759/cureus.14225 · Cited by 15
Association between Maternal Thyroxine and Risk of Fetal Congenital Heart Defects: A Hospital-Based Cohort Study
Dong, J., Peng, T., Li, M., Xie, F., & Wu, J. (2022) · International Journal of Endocrinology · doi:10.1155/2022/3859388 · Cited by 15
Maternal influenza-like illness, medication use during pregnancy and risk of congenital heart defects in offspring
Li, M., Liu, Z., Lin, Y., Chen, X., Li, S., You, F., Deng, Y., Li, N., Wang, Y., Zhang, Y., et al. (2013) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2013.838950 · Cited by 15
Genetics of Congenital Heart Defects: A Candidate Gene Approach
Lagendijk, A. K., Smith, K., & Bakkers, J. (2010) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2010.10.003 · Cited by 15
Rationale for the Cytogenomics of Cardiovascular Malformations Consortium: A Phenotype Intensive Registry Based Approach
Hinton, R. B., McBride, K. L., Bleyl, S. B., Bowles, N. E., Border, W. L., Garg, V., Smolarek, T. A., Lalani, S. R., & Ware, S. M. (2015) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd2020076 · Cited by 15
Discovery of an Experimental Model of Unicuspid Aortic Valve
Weiss, R. M., Chu, Y., Brooks, R. M., Lund, D. D., Cheng, J. L., Zimmerman, K. A., Kafa, M. K., Sistla, P., Doshi, H. H., Shao, J. Q., et al. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.117.006908 · Cited by 15

Authors: Jenkins, K. J., Correa, A., Feinstein, J. A., Botto, L., Britt, A. E., Daniels, S. R., Elixson, M., Warnes, C. A., & Webb, C. L.
Affiliations: Boston Children's Hospital (US)
ORCID: Jenkins, Kathy J.
Correa, Adolfo
Feinstein, Jeffrey A.
Botto, Lorenzo
Daniels, Stephen R.
Warnes, Carole A.
Webb, Catherine L.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2007-06-12
Volume: 115
Issue: 23
Pages: 2995-3014
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/circulationaha.106.183216
OpenAlex: W2617245041
Cited by: 818
References: 232
Citations by year: 2026: 21 · 2025: 26 · 2024: 50 · 2023: 42 · 2022: 52 · 2021: 42 · 2020: 50 · 2019: 48 · 2018: 52 · 2017: 38 · 2016: 43 · 2015: 61 · 2014: 55 · 2013: 52 · 2012: 48
FWCI: 3.84
Type: journal article
Language: en
Open access: closed
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Congenital heart defects research
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
Keywords: congenital heart disease, modifiable risk factors, fetal heart development, periconceptional folic acid supplementation, maternal rubella infection, phenylketonuria, pregestational diabetes, thalidomide, retinoids, prenatal drug exposure, environmental exposure, paternal exposure, pregnancy monitoring
MeSH terms: Female, Fetal Diseases, Heart Defects, Congenital, Humans, Pregnancy, Risk Factors, Cardiovascular Abnormalities, Maternal Exposure, Dietary Supplements

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Noninherited Risk Factors and Congenital Cardiovascular Defects: Current Knowledge: A Scientific Statement From the American Heart Association Council on Cardiovascular Disease in the Young: Endorsed by the American Academy of Pediatrics

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks