Cited by 140Cardiac Arrhythmias and TreatmentsAtrial Fibrillation Management and OutcomesCardiac electrophysiology and arrhythmias

The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.

Results from the Loire-Ardeche-Drome-Isere-Puy-de-Dome (LADIP) trial on atrial flutter, a multicentric prospective randomized study comparing amiodarone and radiofrequency ablation after the first episode of symptomatic atrial flutter

Open access

Da Costa, Antoine, Thévenin, Jérôme, Roche, Frédéric, Romeyer-Bouchard, Cécile, Abdellaoui, Loucif, Messier, Marc, Denis, Lucien, Faure, Emmanuel, Gonthier, Régis, Kruszynski, Georges, Pages, J. Marie, Bonijoly, Serge, Lamaison, Dominique, Defaye, Pascal, Barthélemy, J. Claude, Gouttard, Thierry, Isaaz, Karl·2006·Circulation

DOI 10.1161/circulationaha.106.638395

Open this paper in CoChat — free account Open PDF

Abstract

BACKGROUND: There is no published randomized study comparing amiodarone therapy and radiofrequency catheter ablation (RFA) after only 1 episode of symptomatic atrial flutter (AFL). The aim of the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) Trial of Atrial Flutter was 2-fold: (1) to prospectively compare first-line RFA (group I) versus cardioversion and amiodarone therapy (group II) after only 1 AFL episode; and (2) to determine the impact of both treatments on the long-term risk of subsequent atrial fibrillation (AF). METHODS AND RESULTS: From October 2002 to February 2006, 104 patients (aged 78+/-5 years; 20 women) with AFL were included, with 52 patients in group I and 52 patients in group II. The cumulative risk of AFL or AF was interpreted with the use of Kaplan-Meier curves and compared by the log-rank test. Clinical presentation, echocardiographic data, and follow-up were as follows: age (78.5+/-5 versus 78+/-5 years), history of AF (27% versus 21.6%); structural heart disease (58% versus 65%), left ventricular ejection fraction (56+/-14% versus 54.5+/-14%), left atrial size (43+/-7 versus 43+/-6 mm), mean follow-up (13+/-6 versus 13+/-6 months; P=NS), recurrence of AFL (3.8% versus 29.5%; P<0.0001), and occurrence of significant AF beyond 10 minutes (25% versus 18%; P=0.3). Five complications (10%) were noted in group II (sick sinus syndrome in 2, hyperthyroidism in 1, and hypothyroidism in 2) and none in group I (0%) (P=0.03). CONCLUSIONS: RFA should be considered a first-line therapy even after the first episode of symptomatic AFL. There is a better long-term success rate, the same risk of subsequent AF, and fewer secondary effects.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1161/circulationaha.106.638395

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Relationships Between Sinus Rhythm, Treatment, and Survival in the Atrial Fibrillation Follow-Up Investigation of Rhythm Management (AFFIRM) Study
The AFFIRM Investigators (2004) · Circulation · doi:10.1161/01.cir.0000121736.16643.11 · Cited by 1,202
Amiodarone to Prevent Recurrence of Atrial Fibrillation
Roy, D., Talajic, M. R., Dorian, P., Connolly, S. J., Eisenberg, M. J., Green, M. S., Kuś, T., Lambert, J., Dubuc, M., Gagné, P., et al. (2000) · New England Journal of Medicine · doi:10.1056/nejm200003303421302 · Cited by 1,142
Untitled work
Blomstrom-Lundqvist (2003) · doi:10.1161/01.cir.0000091380.04100.84 · Cited by 955
Preoperative Amiodarone as Prophylaxis against Atrial Fibrillation after Heart Surgery
Daoud, E. G., Strickberger, S. A., Man, K. C., Goyal, R., Deeb, G. M., Bolling, S. F., Pagani, F. D., Bitar, C., Meissner, M. D., & Morady, F. (1997) · New England Journal of Medicine · doi:10.1056/nejm199712183372501 · Cited by 527
Efficacy of Dofetilide in the Treatment of Atrial Fibrillation-Flutter in Patients With Reduced Left Ventricular Function: A Danish Investigations of Arrhythmia and Mortality ON Dofetilide (DIAMOND) Substudy
Pedersen, O. D., Bagger, H., Keller, N., Marchant, B., Køber, L., & Torp-Pedersen, C. (2001) · Circulation · doi:10.1161/01.cir.104.3.292 · Cited by 496
Prospective randomized comparison of antiarrhythmic therapy versus first-line radiofrequency ablation in patients with atrial flutter
Natale, A., Newby, K. H., Pisanó, E., Leonelli, F., Fanelli, R., Potenza, D., Beheiry, S., & Tomassoni, G. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00635-5 · Cited by 414
Incidence and predictors of atrial flutter in the general population
Granada, J., Uribe, W., Chyou, P.-H., Maassen, K., Vierkant, R., Smith, P. N., Hayes, J., Eaker, E., & Vidaillet, H. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(00)00982-7 · Cited by 375
Atrial flutter in the young: A collaborative study of 380 cases
Garson, A., Bink‐Boelkens, M. T. E., Hesslein, P. S., Hordof, A. J., Keane, J. F., Neches, W. H., & Porter, C.-B. J. (1985) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(85)80497-6 · Cited by 347
Electrophysiological Effects of Catheter Ablation of Inferior Vena Cava–Tricuspid Annulus Isthmus in Common Atrial Flutter
CAUCHEMEZ, B., Haı̈ssaguerre, M., Fischer, B., Thomas, O., Clémenty, J., & Coumel, P. (1996) · Circulation · doi:10.1161/01.cir.93.2.284 · Cited by 312
Radiofrequency Catheter Ablation of Atrial Flutter
Poty, H., Saoudi, N. C., Nair, M., Anselme, F., & Letac, B. (1996) · Circulation · doi:10.1161/01.cir.94.12.3204 · Cited by 295

Flagged first, then by citations

Show all 39 references

Research works printed but not linked: 7

10.1161/circ.99.4.534 · DOI
10.1161/circ.98.4.315 · DOI
10.1161/circ.94.12.3204 · DOI
10.1161/circ.93.2.284 · DOI
10.1161/circ.100.25.2507 · DOI
10.1161/circ.103.10.1434 · DOI
10.1161/circ.104.3.292 · DOI

Sorted by citations

Items 101–139 of 139

Failed Pacemaker Detection of Flecainide-Induced Atrial Flutter With One-to-One Atrioventricular Conduction
Wurtz, P. J., Pearman, J., & Bush, K. N. V. (2025) · JACC Case Reports · doi:10.1016/j.jaccas.2025.103365 · Cited by 1
Relationship between Holter findings immediately after ablation of typical atrial flutter and subsequent risk of atrial fibrillation
Moubarak, G., Pavin, D., Béhar, N., Martins, R. P., Bouleti, C., Leclercq, C., Daubert, J., & Mabo, P. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.03.013 · Cited by 1
An unusual propagation pattern along the tricuspid annulus after cavo-tricuspid isthmus ablation: Insights into posterior transverse conduction revealed by an ultra-high-resolution 3-dimensional mapping system
Kanda, T., Masuda, M., Kurata, N., Matsuda, Y., Osamu, I., Asai, M., & Mano, T. (2018) · Journal of Cardiology Cases · doi:10.1016/j.jccase.2018.12.006 · Cited by 1
The Year in Review of Clinical Cardiac Electrophysiology
Scheinman, M. M., & Keung, E. C. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.02.055 · Cited by 1
Supraventricular tachycardia
Abedin, F. Z. (2013) · doi:10.1002/9781118521991.ch5 · Cited by 1
Supraventricular Tachycardia
Penny-Peterson, E., & Naccarelli, G. V. (2009) · Wiley eBooks · doi:10.1002/9781444309768.ch39 · Cited by 1
The Potential Role of Nonpharmacologic Electrophysiology-Based Interventions in Improving Outcomes in Patients Hospitalized for Heart Failure
Wang, N. C., Piccini, J. P., Fonarow, G. C., Knight, B. P., Harinstein, M. E., Butler, J., Lahiri, M. K., Metra, M., Vaduganathan, M., & Gheorghiade, M. (2013) · Heart Failure Clinics · doi:10.1016/j.hfc.2013.04.007
Tratamiento de las taquiarritmias por métodos no farmacológicos. Ablaciones. Desfibriladores
Saint‐Gerons, J. M. S., Mazuelos, F., Sánchez, M. A., & Cruz-Conde, J. S. D. L. (2009) · Medicine - Programa de Formación Médica Continuada Acreditado · doi:10.1016/s0304-5412(09)72006-2
Simultaneous pulmonary vein cryoablation and cavotricuspid isthmus radiofrequency ablation in patients with combined atrial fibrillation and typical atrial flutter
Peyrol, M., Sbragia, P., Ronchard, T., Cautela, J., Villacampa, C., Laine, M., Bonello, L., Thuny, F., Paganelli, F. F., & Lévy, S. (2015) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2015.03.013
Radiofrekvensablasjon av supraventrikulære takykardier ved UNN i perioden 2004 - 2006.
Eriksen, A. H. (2008) · NORA - Norwegian Open Research Archives
The role of radiofrequency ablation as a first line therapy in the treatment of atrial flutter.
Roşu, R., Mureşan, L., Andronache, M., Pop, D., Pop, C., Pușchiță, M., Mălai, A., Guşetu, G., & Zdrenghea, D. T. (2010) · PubMed
Supraventricular Tachycardia
(1953) · New England Journal of Medicine · doi:10.1056/nejm195304022481413
Results From the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) Trial on Atrial Flutter, a Multicentric Prospective Randomized Study Comparing Amiodarone and Radiofrequency Ablation After the First Episode of Symptomatic Atrial Flutter
Waldo, A. L. (2007) · Yearbook of Cardiology · doi:10.1016/s0145-4145(08)70266-1
Catheter Ablation vs. Amiodarone for First Atrial Flutter in Elders
Link, M. S. (2006) · Journal watch · doi:10.1056/jc200611140000004
Cryoablation of Atrial Flutter
Andrew, P. S., & MONTENERO, A. S. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-1615-3.00013-7
Electrocardiographic Manifestations of the Athlete's Heart and Management of Arrhythmias in the Athlete
Sharma, S., Rawlins, J., & McKenna, W. J. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-0285-9.00053-3
Typical and Atypical Atrial Flutter
Nalliah, C. J., Kumar, S., Sanders, P., & Kalman, J. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-44733-1.00075-4
The Electrophysiology Laboratory and Electrophysiologic Procedures
Krishnan, S. (2011) · Elsevier eBooks · doi:10.1016/b978-0-323-07902-0.10006-6
MANAGEMENT APPROACHES FOR PATIENTS WITH SUPRAVENTRICULAR TACHYCARDIAS AND HIGH RISK OF SUDDEN CARDIAC DEATH: A REVIEW OF CURRENT GUIDELINES
Mamchur, S. E., Александрович, Х. Е., Chichkova, T. Y., & Романова, М. П. (2018) · Complex Issues of Cardiovascular Diseases · doi:10.17802/2306-1278-2018-7-3-117-128
Cavotricuspid isthmus-dependent atrial flutter: clinical perspectives
Bun, S., Lațcu, D. G., Wedn, A. M., Hasni, K., & Saoudi, N. C. (2019) · Research Reports in Clinical Cardiology · doi:10.2147/rrcc.s171326
Ablation of Atrial Flutter with Zero Fluoroscopy Approach
Russo, V., Bottino, R., Rago, A., Proietti, R., Cassese, A., Ciardiello, C., & Nigro, G. (2019) · Springer eBooks · doi:10.1007/978-3-030-16992-3_10
Trastornos del ritmo auricular
Pambrun, T., Denis, A., Derval, N., Duchâteau, J., Klotz, N., Sacher, F., Jaı̈s, P., Haı̈ssaguerre, M., & Hocini, M. (2019) · EMC - Tratado de Medicina · doi:10.1016/s1636-5410(19)42595-6
Typical and Atypical Atrial Flutter
Kumar, S., Sanders, P., & Kalman, J. M. (2013) · Elsevier eBooks · doi:10.1016/b978-1-4557-2856-5.00074-1
Guias de ablacion de arritmias cardiacas de la Federacion Argentina de Cardiologia
Keegan, R., Aguinaga, L., Secchi, J., Pozzer, D. L., Valentino, M., Femenía, F., Río, A. D., Feo, M. D., Bravo, A., & Martellotto, A. (2012)
Taquicardias supraventriculares en adultos (a excepción de la fibrilación auricular)
Bénali, K., Galand, V., Mabo, P., & Martins, R. P. (2021) · EMC - Tratado de Medicina · doi:10.1016/s1636-5410(21)45705-3
Tachicardie sopraventricolari dell’adulto (esclusa la fibrillazione atriale)
Bénali, K., Galand, V., Mabo, P., & Martins, R. P. (2021) · EMC - AKOS - Trattato di Medicina · doi:10.1016/s1634-7358(21)45773-6
Atrial tachycardias
Katritsis, D. G., & Morady, F. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-79338-4.00021-2
Catheter ablation of atrial flutter: Critical isthmus identification and localization
Shamloo, A. S., & Hindricks, G. (2020) · Revista Portuguesa de Cardiologia (English Edition) · doi:10.1016/j.repce.2020.10.016
Méthodes ablatives
GODIN, B., Savouré, A., & Anselme, F. (2012) · EMC - Cardiologie · doi:10.1016/s1166-4568(12)53121-9
Outcome of the elective or online radiofrequency ablation of typical atrial flutter
Iori, M., Quartieri, F., Battista, A., Donateo, P., Navazio, A., Brignole, M., & Bottoni, N. (2023) · Minerva Cardiology and Angiology · doi:10.23736/s2724-5683.20.05380-3
Predictors of 5-year arrhythmia recurrence after treatment of typical atrial flutter in patients with coronary artery disease
Potapova, K. V., Носов, В. П., & Koroleva, L. Y. (2025) · Kazan medical journal · doi:10.17816/kmj634175
Ablation of Right Atrial Flutter in a Sub-Saharan African Country: Experience of Lome (Togo)
Pessinaba, S., Essaga, C. E., Afassinou, Y. M., Yayehd, K., Kpélafia, M., Ngayou, L. I., Kaziga, W. D., Togbossi, E., Baragou, S., Damorou, F., et al. (2025) · World Journal of Cardiovascular Diseases · doi:10.4236/wjcd.2025.156027
Fluoroless cavotricuspid isthmus ablation of typical atrial flutter achieves success with shorter radiofrequency and procedural times
Jacint, S., Portugal, G., Santos, H., Cunha, P. S., Valente, B. T., Lousinha, A., Delgado, A. S., Ferreira, R. C., & Oliveira, M. M. (2025) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2025.04.005
The Never Old‐Fashioned Right Atrial Flutter Revisited
Costa, A. D., & Bénali, K. (2025) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.70082
Fibrilación y flúter auricular
Fraile, P. Z., Castellano, N. P., García-Bello, E., Ferrer, J. J. G., & Villacastín, J. P. (2025) · Medicine - Programa de Formación Médica Continuada Acreditado · doi:10.1016/j.med.2025.09.010
Radiofrequency Ablation of Atrial Fibrillation and Atrial Flutter: Who and When?
Kautzner, J., & Wichterle, D. (2007) · Springer eBooks · doi:10.1007/978-88-470-0636-2_4
Safety and Feasibility of Dual‐Energy Lattice‐Tip Catheter for Cavotricuspid Isthmus Ablation in Patients With Cardiac Implantable Electronic Devices: A Single‐Center Experience
Hanna, D., Rodriguez, B., Grabarczyk, G., Perez-Hernandez, J., Venn, R. A., Rechani, L. E., Sublette, S. M., & Sharma, D. (2026) · Journal of Cardiovascular Electrophysiology · doi:10.1111/jce.70333
Arrhythmias in d-transposition of the great arteries after Mustard- or Senning-type atrial redirection surgery: 22 years of experience in catheter ablation and follow-up
Neumann, S. G., Voth, S., Jerosch‐Herold, M., Veltmann, C., & Hebe, J. (2026) · Heart Rhythm · doi:10.1016/j.hrthm.2026.07.049
Catheter Ablation of Atrial Flutter and Atrial Fibrillation
Marine, J. E., & Calkins, H. G. (2010) · Humana Press eBooks · doi:10.1007/978-1-60761-161-5_9

Authors: Da Costa, A., Thévenin, J., Roche, F., Romeyer-Bouchard, C., Abdellaoui, L., Messier, M., Denis, L., Faure, E., Gonthier, R., Kruszynski, G., Pages, J. M., Bonijoly, S., Lamaison, D., Defaye, P., Barthélemy, J. C., Gouttard, T., & Isaaz, K.
Affiliations: From the Division of Cardiology (A.D.C., J.T., C.R.-B., K.I.), Department of Physiology (F.R., J.C.B.), University Jean Monnet in Saint-Etienne, Saint-Etienne, France; Division of Cardiology, Firminy Hospital, Firminy, France (L.A.); Bakken Research Center, Maastricht, Netherlands (M.M.); Division of Cardiology, Saint-Chamond Hospital, Saint-Chamond, France (L.D.); Division of Cardiology, Valence Hospital, Valence, France (E.F.); Department of Medicine for the Elderly, La Charité Hospital, Saint...
Université Jean Monnet (FR)
ORCID: Messier, Marc
Defaye, Pascal
Isaaz, Karl
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2006-10-17
Volume: 114
Issue: 16
Pages: 1676-1681
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/circulationaha.106.638395
OpenAlex: W2065695293
Cited by: 140
References: 39
Citations by year: 2026: 2 · 2025: 13 · 2024: 5 · 2023: 6 · 2022: 3 · 2021: 8 · 2020: 6 · 2019: 8 · 2018: 3 · 2017: 2 · 2016: 7 · 2015: 11 · 2014: 5 · 2013: 7 · 2012: 10
FWCI: 7.11
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords: atrial flutter, radiofrequency catheter ablation, amiodarone, cardioversion, atrial fibrillation recurrence, first-line therapy, treatment complications, sick sinus syndrome, hyperthyroidism, hypothyroidism, elderly patients, structural heart disease, left atrial size, left ventricular ejection fraction
MeSH terms: Aged, Aged, 80 and over, Amiodarone, Atrial Flutter, Female, Follow-Up Studies, France, Humans, Male, Prospective Studies, Treatment Outcome, Catheter Ablation

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Results from the Loire-Ardeche-Drome-Isere-Puy-de-Dome (LADIP) trial on atrial flutter, a multicentric prospective randomized study comparing amiodarone and radiofrequency ablation after the first episode of symptomatic atrial flutter

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks