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Cited by 656Diabetes, Cardiovascular Risks, and LipoproteinsHealthcare Systems and Public HealthCardiovascular Health and Risk Factors

The DOI matches its Crossref record, with a small difference in title or year; 37 of the 38 references it cites were found in a registry or an index.

Increasing Cardiovascular Disease Burden Due to Diabetes Mellitus: The Framingham Heart Study

Fox, Caroline S., Coady, Sean, Sorlie, Paul D., D’Agostino, Ralph B., Pencina, Michael J., Vasan, Ramachandran S., Meigs, James B., Levy, Daniel, Savage, Peter J.·2007·Circulation
DOI 10.1161/circulationaha.106.658948
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Abstract

Background— Marked reductions in cardiovascular disease (CVD) morbidity and mortality have occurred in the United States over the last 50 years. We tested the hypothesis that the relative burden of CVD attributable to diabetes mellitus (DM) has increased over the past 5 decades. Methods and Results— Participants aged 45 to 64 years from the Framingham Heart Study, who attended examinations in an “early” time period (1952 to 1974), were compared with those who attended examinations in a later time period (1975 to 1998). The risk of CVD events (n=133 among those with and 1093 among those without DM) attributable to DM in the 2 time periods was assessed with Cox proportional hazards models; population attributable risk of DM as a CVD risk factor was calculated for each time period. The age- and sex-adjusted hazard ratio for DM as a CVD risk factor was 3.0 (95% CI, 2.3 to 3.9) in the earlier time period and 2.5 (95% CI, 1.9 to 3.2) in the later time period. The population attributable risk for DM as a CVD risk factor increased from 5.4% (95% CI, 3.8% to 6.9%) in the earlier time period to 8.7% (95% CI, 5.9% to 11.4%) in the later time period ( P for attributable risk ratio=0.04), although multivariable adjustment resulted in attenuation of these findings ( P =0.12); most of these observations were found among men. Conclusions— The proportion of CVD attributable to DM has increased over the past 50 years in Framingham. These findings emphasize the need for increased efforts to prevent DM and to aggressively treat and control CVD risk factors among those with DM.

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Crossref · 10.1161/circulationaha.106.658948

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Research works printed but not linked: 4

  1. Self-reported heart disease and stroke among adults with and without diabetes: United States, 1999–2001. MMWR Morb Mortal Wkly Rep. 2003; 52: 1065–1070.
  2. 10.1001/jama.1994.03520030047027 · DOI
  3. 10.1161/circ.98.23.2513 · DOI
  4. 10.1161/circ.102.9.1014 · DOI

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Metadata

Authors
Fox, C. S., Coady, S., Sorlie, P. D., D’Agostino, R. B., Pencina, M. J., Vasan, R. S., Meigs, J. B., Levy, D., & Savage, P. J.
Affiliations
Boston University (US)
ORCID
Venue
Circulation
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2007-03-27
Volume
115
Issue
12
Pages
1544-1550
ISSN
  • 0009-7322 (ISSN-L)
  • 1524-4539
DOI
10.1161/circulationaha.106.658948
OpenAlex
W2055416829
Cited by
656
References
38
Citations by year
2026: 11 · 2025: 15 · 2024: 20 · 2023: 19 · 2022: 35 · 2021: 25 · 2020: 27 · 2019: 23 · 2018: 32 · 2017: 38 · 2016: 42 · 2015: 46 · 2014: 49 · 2013: 35 · 2012: 52
FWCI
33.94
Type
journal article
Language
en
Open access
closed
Locations
  • Circulation (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (n01hc25195-41-0-1)
  • U.S. Public Health Service (5K24H004334)
  • National Heart, Lung, and Blood Institute (N01‐HC25195)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords
diabetes mellitus, cardiovascular disease, population attributable risk, cardiovascular risk factors, temporal trends, Framingham Heart Study, middle-aged adults, diabetes prevention, cardiovascular risk management
MeSH terms
Blood Glucose, Cardiovascular Diseases, Diabetes Mellitus, Female, Humans, Hypertension, Male, Middle Aged, Obesity, Risk, Risk Factors, Smoking, United States, Cohort Studies, Incidence, Proportional Hazards Models, Diabetes Complications

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