The DOI matches its Crossref record; 153 of the 153 references it cites were found in a registry or an index.
Drug Therapy of High-Risk Lipid Abnormalities in Children and Adolescents: A Scientific Statement From the American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee, Council of Cardiovascular Disease in the Young, With the Council on Cardiovascular Nursing
Abstract
Despite compliance with lifestyle recommendations, some children and adolescents with high-risk hyperlipidemia will require lipid-lowering drug therapy, particularly those with familial hypercholesterolemia. The purpose of this statement is to examine new evidence on the association of lipid abnormalities with early atherosclerosis, discuss challenges with previous guidelines, and highlight results of clinical trials with statin therapy in children and adolescents with familial hypercholesterolemia or severe hypercholesterolemia. Recommendations are provided to guide decision-making with regard to patient selection, initiation, monitoring, and maintenance of drug therapy.
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“Furthermore, there are data to suggest that care for T1D has improved as evidenced by reduced rates of microvascular disease in the past decades109–111, whereas data on CVD suggest that substantially less progress has been made in reduction of macrovascular disease rates111–113.”
From Epidemiology of type 1 diabetes (2010) · cites this paper as [112]
In the citing paper
“the AHA categorizes type 1 children in the highest tier for cardiovascular risk and recommends both lifestyle and pharmacologic treatment for those with elevated LDL cholesterol levels (285,286).”
From Standards of Medical Care in Diabetes—2009 (2009) · cites this paper as [286]
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Metadata
- Authors
- McCrindle, B. W., Urbina, E. M., Dennison, B. A., Jacobson, M. S., Steinberger, J., Rocchini, A. P., Hayman, L. L., & Daniels, S. R.
- Affiliations
- Hospital for Sick Children (CA)
- ORCID
- Venue
- Circulation
- Published
- 2007-04-10
- Volume
- 115
- Issue
- 14
- Pages
- 1948-1967
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2070344375
- Cited by
- 418
- References
- 153
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 5 · 2023: 5 · 2022: 5 · 2021: 8 · 2020: 19 · 2019: 11 · 2018: 7 · 2017: 12 · 2016: 18 · 2015: 23 · 2014: 26 · 2013: 32 · 2012: 36
- FWCI
- 53.43
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Circulation (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipid metabolism and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Keywords
- familial hypercholesterolemia, severe hypercholesterolemia, lipid-lowering therapy, statins, early atherosclerosis, children and adolescents, patient selection, treatment monitoring
- MeSH terms
- Contraindications, Adolescent, Adult, Age Factors, Anticholesteremic Agents, Hypolipidemic Agents, Arteriosclerosis, Child, Child, Preschool, Cholesterol, Dietary, Clinical Trials as Topic, Combined Modality Therapy, Dietary Fats, Exercise Therapy, Female, Humans, Hyperlipoproteinemia Type II, Hyperlipoproteinemias, Infant, Cholesterol, LDL, Male, Phytotherapy, Middle Aged, Obesity, Risk Factors, Ultrasonography, HIV Infections, HIV Protease Inhibitors, Age of Onset, Disease Progression, Diet, Fat-Restricted, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Metabolic Syndrome, Diabetes Complications, Dyslipidemias
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