The DOI matches its Crossref record; 107 of the 107 references it cites were found in a registry or an index.
Coronary Microembolization: From Bedside to Bench and Back to Bedside
Abstract
Coronary microembolization from the erosion or rupture of a vulnerable atherosclerotic plaque occurs spontaneously in acute coronary syndromes and iatrogenically during percutaneous coronary interventions. Typical consequences of coronary microembolization are microinfarcts with an inflammatory response, contractile dysfunction, and reduced coronary reserve. Apart from transient elevations of creatine kinase and troponin, microemboli can be visualized by intracoronary Doppler and the resulting microinfarcts by late-enhancement nuclear magnetic resonance. Statins, antiplatelet agents, and coronary vasodilators protect against microembolization and microinfarction when started before percutaneous coronary interventions. Distal protection devices can retrieve atherothrombotic debris and prevent its embolization into the microcirculation, but their effect on clinical outcome has been disappointing so far, except for saphenous vein bypass grafts. Devices for aspiration of thrombi and thrombus-derived vasoconstrictor, thrombogenic, and inflammatory substances, however, reduce thrombus burden, improve perfusion, and provide protection in patients with acute myocardial infarction.
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Cites
Intensive versus Moderate Lipid Lowering with Statins after Acute Coronary Syndromes
Cannon, C. P., Braunwald, E., McCabe, C. H., Rader, D. J., Rouleau, J. L., Belder, R., Joyal, S. V., Hill, K. A., Pfeffer, M. A., & Skene, A. M. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040583 · Cited by 4,938
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Pathology of the Vulnerable Plaque
Virmani, R., Burke, A. P., Farb, A., & Kolodgie, F. D. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2005.10.065 · Cited by 2,315
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(1997) · New England Journal of Medicine · doi:10.1056/nejm199706123362401 · Cited by 1,883
Guidelines for Percutaneous Coronary Interventions
Silber, S., Albertsson, P., Avilés, F. F., Camici, P. G., Colombo, A., Hamm, C., Jørgensen, E., Marco, J., Nordrehaug, J.-E., Ruzyllo, W., et al. (2005) · European Heart Journal · doi:10.1093/eurheartj/ehi138 · Cited by 1,609
Thrombus Aspiration during Primary Percutaneous Coronary Intervention
Svilaas, T., Vlaar, P. J., van der Horst, I. C., Diercks, G. F. H., de Smet, B. J. G. L., van den Heuvel, A. F. M., Anthonio, R. L., Jessurun, G. A., Tan, E.-S., Suurmeijer, A. J. H., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706416 · Cited by 1,071
The Prognostic Value of Serum Troponin T in Unstable Angina
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Vlaar, P. J., Svilaas, T., van der Horst, I. C., Diercks, G. F., Fokkema, M. L., de Smet, B. J., van den Heuvel, A. F., Anthonio, R. L., Jessurun, G. A., Tan, E.-S., et al. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60833-8 · Cited by 900
Cited by
Myocardial ischemia-reperfusion injury: a neglected therapeutic target
Hausenloy, D. J., & Yellon, D. M. (2013) · Journal of Clinical Investigation · doi:10.1172/jci62874 · Cited by 2,357
Cardiovascular remodelling in coronary artery disease and heart failure
Heusch, G., Libby, P., Gersh, B., Yellon, D., Böhm, M., Lopaschuk, G., & Opie, L. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60107-0 · Cited by 734
Self-citationMultitarget Strategies to Reduce Myocardial Ischemia/Reperfusion Injury
Davidson, S. M., Ferdinandy, P., Andreadou, I., Bøtker, H. E., Heusch, G., Ibáñez, B., Ovize, M., Schulz, R., Yellon, D. M., Hausenloy, D. J., et al. (2019) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2018.09.086 · Cited by 699
Self-citationHeusch, G., & Gersh, B. J. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw224 · Cited by 676
Self-citationGuidelines for experimental models of myocardial ischemia and infarction
Lindsey, M. L., Bolli, R., Canty, J. M., Du, X.-J., Frangogiannis, N. G., Frantz, S., Gourdie, R. G., Holmes, J. W., Jones, S. P., Kloner, R. A., et al. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00335.2017 · Cited by 526
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Metadata
- Authors
- Heusch, G., Kleinbongard, P., Böse, D., Levkau, B., Haude, M., Schulz, R., & Erbel, R.
- Venue
- Circulation
- Published
- 2009-11-03
- Volume
- 120
- Issue
- 18
- Pages
- 1822-1836
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2080276645
- Cited by
- 419
- References
- 107
- FWCI
- 34.14
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Coronary Microembolization: From Bedside to Bench and Back to Bedside. https://app.cochat.ai/papers/10.1161/circulationaha.109.888784
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- Heusch, G., Kleinbongard, P., Böse, D., Levkau, B., Haude, M., Schulz, R., & Erbel, R. (2009). Coronary Microembolization: From Bedside to Bench and Back to Bedside. Circulation. https://doi.org/10.1161/circulationaha.109.888784
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
