The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Endothelial Function in Resistance and Conduit Arteries and 5-Year Risk of Cardiovascular Disease
Open accessAbstract
Background—: Impaired endothelial function has been implicated as a cause of cardiovascular disease. Little is known of the relations of measures of endothelial function in resistance and conduit arteries to incident cardiovascular disease in the general population, and available techniques have not been compared. Methods and Results—: In 1016 participants (70 years of age) of the population-based Prospective Study of the Vasculature in Uppsala Seniors (PIVUS) study (52% women), we measured endothelium-dependent vasodilation using the invasive forearm technique with acetylcholine given in the brachial artery, the brachial artery ultrasound technique with measurement of flow-mediated dilatation, and the pulse-wave analysis–based method with β-2-agonist terbutaline provocation. During 5 years of follow-up, 101 participants experienced a composite end point of myocardial infarction, stroke, or death, excluding the 85 persons with a history of myocardial infarction or stroke at baseline. In logistic regression models adjusted for several established and novel cardiovascular disease risk factors and medications, endothelium-dependent vasodilation by the invasive forearm technique with acetylcholine was associated with risk of the end point (odds ratio, 0.72 per SD; 95% confidence interval, 0.56 to 0.93; P =0.01). Endothelial function by the other 2 methods was not related to risk of the end point. Addition of endothelium-dependent vasodilation to the Framingham risk score improved discrimination of risk of the end point. Conclusions—: Endothelium-dependent vasodilation in resistance arteries, but not in the brachial conduit artery (flow-mediated dilatation), was associated with 5-year risk of a composite end point of death, myocardial infarction, or stroke independently of major cardiovascular disease risk factors. This vascular measurement improved risk discrimination when added to an established risk score in an elderly population.
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General Cardiovascular Risk Profile for Use in Primary Care: The Framingham Heart Study
D’Agostino, R. B., Vasan, R. S., Pencina, M. J., Wolf, P. A., Cobain, M., Massaro, J. M., & Kannel, W. B. (2008) · Circulation · doi:10.1161/circulationaha.107.699579 · Cited by 7,491
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
Celermajer, D. S., Sorensen, K. E., Gooch, V. M., Spiegelhalter, D. J., Miller, O. I., Sullivan, I. D., Lloyd, J. K., & Deanfield, J. E. (1992) · The Lancet · doi:10.1016/0140-6736(92)93147-f · Cited by 4,742
Close Relation of Endothelial Function in the Human Coronary and Peripheral Circulations
Anderson, T. J., Uehata, A., Gerhard, M. D., Meredith, I. T., Knab, S., Delagrange, D., Lieberman, E. H., Ganz, P., Creager, M. A., Yeung, A. C., et al. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(95)00327-4 · Cited by 2,033 · cited 1×
“3) Systolic blood pressure, mm Hg 150 (23) Diastolic blood pressure, mm Hg 79 (10) LDL cholesterol, mmol/L 3.”
BackgroundYeboah, J., Folsom, A. R., Burke, G. L., Johnson, C., Polak, J. F., Post, W., Lima, J. A., Crouse, J. R., & Herrington, D. M. (2009) · Circulation · doi:10.1161/circulationaha.109.864801 · Cited by 888
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Cited by
Vlachopoulos, C., Xaplanteris, P., Aboyans, V., Brodmann, M., Cífková, R., Cosentino, F., De Carlo, M., Gallino, A., Landmesser, U., Laurent, S., et al. (2015) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2015.05.007 · Cited by 716
SIRT‐1 and vascular endothelial dysfunction with ageing in mice and humans
Donato, A. J., Magerko, K. A., Lawson, B. R., Durrant, J. R., Lesniewski, L. A., & Seals, D. R. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.211219 · Cited by 271
Zarzuelo, M. J., López-Sepúlveda, R., Sánchez, M., Romero, M., Gómez-Guzmán, M., Ungvary, Z., Pérez-Vizcaíno, F., Jiménez, R., & Duarte, J. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.02.015 · Cited by 202
Jones, A. M., Vanhatalo, A., Seals, D. R., Rossman, M. J., Piknova, B., & Jonvik, K. L. (2021) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002470 · Cited by 156
Johnson, A. W., Kinzenbaw, D. A., Modrick, M. L., & Faraci, F. M. (2013) · Hypertension · doi:10.1161/hypertensionaha.111.00299 · Cited by 63
Metadata
- Authors
- Lind, L., Berglund, L., Larsson, A., & Sundström, J.
- Venue
- Circulation
- Published
- 2011-04-12
- Volume
- 123
- Issue
- 14
- Pages
- 1545-1551
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2041293047
- Cited by
- 218
- References
- 5
- FWCI
- 13.74
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Lind, L., Berglund, L., Larsson, A., & Sundström, J. (2011). Endothelial Function in Resistance and Conduit Arteries and 5-Year Risk of Cardiovascular Disease. Circulation. https://doi.org/10.1161/circulationaha.110.984047
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