The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.
Slow Breathing Increases Arterial Baroreflex Sensitivity in Patients With Chronic Heart Failure
Abstract
Background — It is well established that a depressed baroreflex sensitivity may adversely influence the prognosis in patients with chronic heart failure (CHF) and in those with previous myocardial infarction. Methods and Results — We tested whether a slow breathing rate (6 breaths/min) could modify the baroreflex sensitivity in 81 patients with stable (2 weeks) CHF (age, 58±1 years; NYHA classes I [6 patients], II [33], III [27], and IV [15]) and in 21 controls. Slow breathing induced highly significant increases in baroreflex sensitivity, both in controls (from 9.4±0.7 to 13.8±1.0 ms/mm Hg, P <0.0025) and in CHF patients (from 5.0±0.3 to 6.1±0.5 ms/mm Hg, P <0.0025), which correlated with the value obtained during spontaneous breathing ( r =+0.202, P =0.047). In addition, systolic and diastolic blood pressure decreased in CHF patients (systolic, from 117±3 to 110±4 mm Hg, P =0.009; diastolic, from 62±1 to 59±1 mm Hg, P =0.02). Conclusions — These data suggest that in patients with CHF, slow breathing, in addition to improving oxygen saturation and exercise tolerance as has been previously shown, may be beneficial by increasing baroreflex sensitivity.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Cardiovascular neural regulation explored in the frequency domain.
Malliani, A., Pagani, M., Lombardi, F., & Cerutti, S. (1991) · Circulation · doi:10.1161/01.cir.84.2.482 · Cited by 3,569
Rovere, M. T. L., Bigger, J. T., Marcus, F. I., Mortara, A., & Schwartz, P. J. (1998) · The Lancet · doi:10.1016/s0140-6736(97)11144-8 · Cited by 3,120
Coats, A. J., Adamopoulos, S., Radaelli, A., McCance, A., Meyer, T. E., Bernardi, L., Solda, P. L., Davey, P., Ormerod, O., & Forfar, C. (1992) · Circulation · doi:10.1161/01.cir.85.6.2119 · Cited by 955
Self-citationMortara, A., La Rovere, M. T., Pinna, G. D., Prpa, A., Maestri, R., Febo, O., Pozzoli, M., Opasich, C., & Tavazzi, L. (1997) · Circulation · doi:10.1161/01.cir.96.10.3450 · Cited by 443
Ponikowski, P., Chua, T. P., Piepoli, M., Ondusova, D., Webb-Peploe, K., Harrington, D., Anker, S. D., Volterrani, M., Colombo, R., Mazzuero, G., et al. (1997) · Circulation · doi:10.1161/01.cir.96.8.2586 · Cited by 271
Effect of breathing rate on oxygen saturation and exercise performance in chronic heart failure
Bernardi, L., Spadacini, G., Bellwon, J., Hajric, R., Roskamm, H., & Frey, A. W. (1998) · The Lancet · doi:10.1016/s0140-6736(97)10341-5 · Cited by 249
Self-citationYoga and chemoreflex response to hypoxia and hypercapnia
Spicuzza, L., Gabutti, A., Porta, C., Montano, N., & Bernardi, L. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02881-6 · Cited by 157
Self-citationRespiratory Modulation of Muscle Sympathetic Nerve Activity in Patients With Chronic Heart Failure
Goso, Y., Asanoi, H., Ishise, H., Kameyama, T., Hirai, T., Nozawa, T., Takashima, S., Umeno, K., & Inoue, H. (2001) · Circulation · doi:10.1161/hc2901.093111 · Cited by 121
Low doses of scopolamine increase cardiac vagal tone in the acute phase of myocardial infarction.
Casadei, B., Pipilis, A., Sessa, F., Conway, J., & Sleight, P. (1993) · Circulation · doi:10.1161/01.cir.88.2.353 · Cited by 101
Respiratory correlates of muscle sympathetic nerve activity in heart failure.
Naughton, M. T., Floras, J. S., Rahman, M. A., Jamal, M., & Bradley, T. D. (1998) · PubMed · Cited by 51
Cited by
Heart Rate Variability Biofeedback Increases Baroreflex Gain and Peak Expiratory Flow
Lehrer, P. M., Vaschillo, E., Vaschillo, B., Lu, S.-E., Eckberg, D. L., Edelberg, R., Shih, W. J., Lin, Y., Kuusela, T. A., Tahvanainen, K. U. O., et al. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000089200.81962.19 · Cited by 497
Characteristics of Resonance in Heart Rate Variability Stimulated by Biofeedback
Vaschillo, E. G., Vaschillo, B., & Lehrer, P. M. (2006) · Applied Psychophysiology and Biofeedback · doi:10.1007/s10484-006-9009-3 · Cited by 411
Joseph, C. N., Porta, C., Casucci, G., Casiraghi, N., Maffeis, M., Rossi, M., & Bernardi, L. (2005) · Hypertension · doi:10.1161/01.hyp.0000179581.68566.7d · Cited by 394
Self-citationDynamic interactions between musical, cardiovascular, and cerebral rhythms in humans.
Bernardi, L., Porta, C., Casucci, G., Balsamo, R., Bernardi, N. F., Fogari, R., & Sleight, P. (2009) · Circulation · doi:10.1161/circulationaha.108.806174 · Cited by 348
Self-citationHeart rate dynamics during three forms of meditation.
Peng, C.-K., Henry, I. C., Mietus, J. E., Hausdorff, J. M., Khalsa, G., Benson, H., & Goldberger, A. L. (2004) · International Journal of Cardiology · doi:10.1016/j.ijcard.2003.02.006 · Cited by 247
Metadata
- Authors
- Bernardi, L., Porta, C., Spicuzza, L., Bellwon, J., Spadacini, G., Frey, A. W., Yeung, L. Y. C., Sanderson, J. E., Pedretti, R., & Tramarin, R.
- Venue
- Circulation
- Published
- 2002-01-15
- Volume
- 105
- Issue
- 2
- Pages
- 143-145
- ISSN
- 0009-7322 (ISSN-L)
- 1524-4539
- OpenAlex
- W2020583682
- Cited by
- 274
- References
- 11
- FWCI
- 4.77
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Slow Breathing Increases Arterial Baroreflex Sensitivity in Patients With Chronic Heart Failure. https://app.cochat.ai/papers/10.1161/hc0202.103311
- The paper
- Bernardi, L., Porta, C., Spicuzza, L., Bellwon, J., Spadacini, G., Frey, A. W., Yeung, L. Y. C., Sanderson, J. E., Pedretti, R., & Tramarin, R. (2002). Slow Breathing Increases Arterial Baroreflex Sensitivity in Patients With Chronic Heart Failure. Circulation. https://doi.org/10.1161/hc0202.103311
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.